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Journal Abstract Search

150 related items for PubMed ID: 36399908

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  • 6. Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property.
    Pagare PP, Rastegar A, Abdulmalik O, Omar AM, Zhang Y, Fleischman A, Safo MK.
    Expert Opin Ther Pat; 2022 Feb; 32(2):115-130. PubMed ID: 34657559
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  • 7. Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin.
    Abdulmalik O, Ghatge MS, Musayev FN, Parikh A, Chen Q, Yang J, Nnamani I, Danso-Danquah R, Eseonu DN, Asakura T, Abraham DJ, Venitz J, Safo MK.
    Acta Crystallogr D Biol Crystallogr; 2011 Nov; 67(Pt 11):920-8. PubMed ID: 22101818
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  • 8. VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions.
    Abdulmalik O, Pagare PP, Huang B, Xu GG, Ghatge MS, Xu X, Chen Q, Anabaraonye N, Musayev FN, Omar AM, Venitz J, Zhang Y, Safo MK.
    Sci Rep; 2020 Nov 20; 10(1):20277. PubMed ID: 33219275
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  • 9. Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin.
    Omar AM, Mahran MA, Ghatge MS, Bamane FH, Ahmed MH, El-Araby ME, Abdulmalik O, Safo MK.
    Molecules; 2016 Aug 13; 21(8):. PubMed ID: 27529207
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  • 10. Targeted modification of furan-2-carboxaldehydes into Michael acceptor analogs yielded long-acting hemoglobin modulators with dual antisickling activities.
    Omar AM, Abdulmalik O, El-Say KM, Ghatge MS, Cyril-Olutayo M, Paredes S, Al-Awadh M, El-Araby ME, Safo MK.
    Chem Biol Drug Des; 2024 Jan 13; 103(1):e14371. PubMed ID: 37798397
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  • 11. Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease.
    Alhashimi RT, Ghatge MS, Donkor AK, Deshpande TM, Anabaraonye N, Alramadhani D, Danso-Danquah R, Huang B, Zhang Y, Musayev FN, Abdulmalik O, Safo MK.
    Biomolecules; 2022 May 12; 12(5):. PubMed ID: 35625623
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  • 12. Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents.
    Pagare PP, Ghatge MS, Chen Q, Musayev FN, Venitz J, Abdulmalik O, Zhang Y, Safo MK.
    J Med Chem; 2020 Dec 10; 63(23):14724-14739. PubMed ID: 33205981
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  • 14. Increased hemoglobin affinity for oxygen with GBT1118 improves hypoxia tolerance in sickle cell mice.
    Dufu K, Williams AT, Muller CR, Walser CM, Lucas A, Eaker AM, Alt C, Cathers BE, Oksenberg D, Cabrales P.
    Am J Physiol Heart Circ Physiol; 2021 Aug 01; 321(2):H400-H411. PubMed ID: 34213392
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  • 16. X-ray crystallography and sickle cell disease drug discovery-a tribute to Donald Abraham.
    Donkor AK, Pagare PP, Mughram MHA, Safo MK.
    Front Mol Biosci; 2023 Aug 01; 10():1136970. PubMed ID: 37293554
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  • 20. Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
    Huang B, Ghatge MS, Donkor AK, Musayev FN, Deshpande TM, Al-Awadh M, Alhashimi RT, Zhu H, Omar AM, Telen MJ, Zhang Y, McMahon TJ, Abdulmalik O, Safo MK.
    Molecules; 2022 Oct 12; 27(20):. PubMed ID: 36296435
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