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178 related items for PubMed ID: 36432094

  • 1. Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Alaaeldin R, Abdel-Rahman IM, Ali FEM, Bekhit AA, Elhamadany EY, Zhao QL, Cui ZG, Fathy M.
    Molecules; 2022 Nov 17; 27(22):. PubMed ID: 36432094
    [Abstract] [Full Text] [Related]

  • 2. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 3. Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis.
    Mohammed HHH, Abbas SH, Hayallah AM, Abuo-Rahma GEA, Mostafa YA.
    Bioorg Chem; 2021 Jan 25; 106():104422. PubMed ID: 33248713
    [Abstract] [Full Text] [Related]

  • 4. 3,7-bis-benzylidene hydrazide ciprofloxacin derivatives as promising antiproliferative dual TOP I & TOP II isomerases inhibitors.
    Samir M, Ramadan M, Abdelrahman MH, Abdelbaset MS, Abourehab MAS, Abdel-Aziz M, Abuo-Rahma GEA.
    Bioorg Chem; 2021 May 25; 110():104698. PubMed ID: 33676043
    [Abstract] [Full Text] [Related]

  • 5. Opposite Effects of Apoptotic and Necroptotic Cellular Pathways on Rotavirus Replication.
    Soliman M, Seo JY, Baek YB, Park JG, Kang MI, Cho KO, Park SI.
    J Virol; 2022 Jan 12; 96(1):e0122221. PubMed ID: 34668777
    [Abstract] [Full Text] [Related]

  • 6. The neurotoxicant PCB-95 by increasing the neuronal transcriptional repressor REST down-regulates caspase-8 and increases Ripk1, Ripk3 and MLKL expression determining necroptotic neuronal death.
    Guida N, Laudati G, Serani A, Mascolo L, Molinaro P, Montuori P, Di Renzo G, Canzoniero LMT, Formisano L.
    Biochem Pharmacol; 2017 Oct 15; 142():229-241. PubMed ID: 28676433
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics.
    Lu Y, Yin W, Alam MS, Kadi AA, Jahng Y, Kwon Y, Rahman AFMM.
    Anticancer Agents Med Chem; 2020 Oct 15; 20(4):464-475. PubMed ID: 31763968
    [Abstract] [Full Text] [Related]

  • 8. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers.
    Abbass EM, Khalil AK, Mohamed MM, Eissa IH, El-Naggar AM.
    Bioorg Chem; 2020 Nov 15; 104():104255. PubMed ID: 32927130
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme.
    Swedan HK, Kassab AE, Gedawy EM, Elmeligie SE.
    J Enzyme Inhib Med Chem; 2023 Dec 15; 38(1):118-137. PubMed ID: 36305290
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of topoisomerase IIα and induction of DNA damage in cholangiocarcinoma cells by altholactone and its halogenated benzoate derivatives.
    Kitdumrongthum S, Reabroi S, Suksen K, Tuchinda P, Munyoo B, Mahalapbutr P, Rungrotmongkol T, Ounjai P, Chairoungdua A.
    Biomed Pharmacother; 2020 Jul 15; 127():110149. PubMed ID: 32344256
    [Abstract] [Full Text] [Related]

  • 11. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():595-611. PubMed ID: 29289884
    [Abstract] [Full Text] [Related]

  • 12. High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway.
    Xu Y, Gao H, Hu Y, Fang Y, Qi C, Huang J, Cai X, Wu H, Ding X, Zhang Z.
    Exp Cell Res; 2019 Sep 15; 382(2):111463. PubMed ID: 31247189
    [Abstract] [Full Text] [Related]

  • 13. B1, a novel topoisomerase II inhibitor, induces apoptosis and cell cycle G1 arrest in lung adenocarcinoma A549 cells.
    Cheng MH, Yang YC, Wong YH, Chen TR, Lee CY, Yang CC, Chen SH, Yang IN, Yang YS, Huang HS, Yang CY, Huang MS, Chiu HF.
    Anticancer Drugs; 2012 Feb 15; 23(2):191-9. PubMed ID: 22008852
    [Abstract] [Full Text] [Related]

  • 14. Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer.
    Chien CM, Yang JC, Wu PH, Wu CY, Chen GY, Wu YC, Chou CK, Tseng CH, Chen YL, Wang LF, Chiu CC.
    Phytomedicine; 2019 Feb 15; 54():109-119. PubMed ID: 30668360
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2013 Jun 28; 11(24):3989-4005. PubMed ID: 23657605
    [Abstract] [Full Text] [Related]

  • 16. Design, molecular modeling and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as inhibitors of topoisomerase II.
    El-Metwally SA, Khalil AK, El-Sayed WM.
    Bioorg Chem; 2020 Jan 28; 94():103492. PubMed ID: 31864673
    [Abstract] [Full Text] [Related]

  • 17. Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies.
    Kadagathur M, Devi GP, Grewal P, Sigalapalli DK, Makhal PN, Banerjee UC, Bathini NB, Tangellamudi ND.
    Bioorg Chem; 2020 Jun 28; 99():103629. PubMed ID: 32272367
    [Abstract] [Full Text] [Related]

  • 18. Quercetin-3-O-glucoside induces human DNA topoisomerase II inhibition, cell cycle arrest and apoptosis in hepatocellular carcinoma cells.
    Sudan S, Rupasinghe HP.
    Anticancer Res; 2014 Apr 28; 34(4):1691-9. PubMed ID: 24692698
    [Abstract] [Full Text] [Related]

  • 19. Oxocrebanine: A Novel Dual Topoisomerase inhibitor, Suppressed the Proliferation of Breast Cancer Cells MCF-7 by Inducing DNA Damage and Mitotic Arrest.
    Yu L, Han S, Lang L, Song H, Zhang C, Dong L, Jia S, Zhang Y, Xiao D, Liu J, Xu Y, Zhang X.
    Phytomedicine; 2021 Apr 28; 84():153504. PubMed ID: 33611211
    [Abstract] [Full Text] [Related]

  • 20. Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
    Someda M, Kuroki S, Miyachi H, Tachibana M, Yonehara S.
    Cell Death Differ; 2020 May 28; 27(5):1539-1553. PubMed ID: 31659279
    [Abstract] [Full Text] [Related]

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