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101 related items for PubMed ID: 3648476

  • 1. The anti-HTLV-III (anti-HIV) and cytotoxic activity of 2',3'-didehydro-2',3'-dideoxyribonucleosides: a comparison with their parental 2',3'-dideoxyribonucleosides.
    Balzarini J, Kang GJ, Dalal M, Herdewijn P, De Clercq E, Broder S, Johns DG.
    Mol Pharmacol; 1987 Jul; 32(1):162-7. PubMed ID: 3648476
    [Abstract] [Full Text] [Related]

  • 2. 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Herdewijn P, Balzarini J, De Clercq E, Pauwels R, Baba M, Broder S, Vanderhaeghe H.
    J Med Chem; 1987 Aug; 30(8):1270-8. PubMed ID: 3497272
    [Abstract] [Full Text] [Related]

  • 3. 2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis.
    Balzarini J, Cooney DA, Dalal M, Kang GJ, Cupp JE, DeClercq E, Broder S, Johns DG.
    Mol Pharmacol; 1987 Dec; 32(6):798-806. PubMed ID: 2826994
    [Abstract] [Full Text] [Related]

  • 4. Effects of 2',3'-dideoxynucleosides on mammalian cells and viruses.
    Waqar MA, Evans MJ, Manly KF, Hughes RG, Huberman JA.
    J Cell Physiol; 1984 Nov; 121(2):402-8. PubMed ID: 6092393
    [Abstract] [Full Text] [Related]

  • 5. Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
    Baba M, Pauwels R, Herdewijn P, De Clercq E, Desmyter J, Vandeputte M.
    Biochem Biophys Res Commun; 1987 Jan 15; 142(1):128-34. PubMed ID: 3028398
    [Abstract] [Full Text] [Related]

  • 6. Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.
    Hao Z, Cooney DA, Hartman NR, Perno CF, Fridland A, DeVico AL, Sarngadharan MG, Broder S, Johns DG.
    Mol Pharmacol; 1988 Oct 15; 34(4):431-5. PubMed ID: 2459590
    [Abstract] [Full Text] [Related]

  • 7. Potent and selective anti-HTLV-III/LAV activity of 2',3'-dideoxycytidinene, the 2',3'-unsaturated derivative of 2',3'-dideoxycytidine.
    Balzarini J, Pauwels R, Herdewijn P, De Clercq E, Cooney DA, Kang GJ, Dalal M, Johns DG, Broder S.
    Biochem Biophys Res Commun; 1986 Oct 30; 140(2):735-42. PubMed ID: 3022729
    [Abstract] [Full Text] [Related]

  • 8. Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
    Balzarini J, Baba M, Pauwels R, Herdewijn P, De Clerq E.
    Biochem Pharmacol; 1988 Jul 15; 37(14):2847-56. PubMed ID: 2840080
    [Abstract] [Full Text] [Related]

  • 9. Development of new potent and selective agents against HIV (human immunodeficiency virus).
    Pauwels R, Schols D.
    Verh K Acad Geneeskd Belg; 1991 Jul 15; 53(6):629-55. PubMed ID: 1816706
    [Abstract] [Full Text] [Related]

  • 10. Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate.
    Hao Z, Cooney DA, Farquhar D, Perno CF, Zhang K, Masood R, Wilson Y, Hartman NR, Balzarini J, Johns DG.
    Mol Pharmacol; 1990 Feb 15; 37(2):157-63. PubMed ID: 1689452
    [Abstract] [Full Text] [Related]

  • 11. Potent and selective activity of 3'-azido-2,6-diaminopurine-2',3'-dideoxyriboside, 3'-fluoro-2,6-diaminopurine-2',3'-dideoxyriboside, and 3'-fluoro-2',3'-dideoxyguanosine against human immunodeficiency virus.
    Balzarini J, Baba M, Pauwels R, Herdewijn P, Wood SG, Robins MJ, de Clercq E.
    Mol Pharmacol; 1988 Mar 15; 33(3):243-9. PubMed ID: 3258404
    [Abstract] [Full Text] [Related]

  • 12. 5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine.
    Balzarini J, Van Aerschot A, Pauwels R, Baba M, Schols D, Herdewijn P, De Clercq E.
    Mol Pharmacol; 1989 May 15; 35(5):571-7. PubMed ID: 2725468
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
    Shi J, McAtee JJ, Schlueter Wirtz S, Tharnish P, Juodawlkis A, Liotta DC, Schinazi RF.
    J Med Chem; 1999 Mar 11; 42(5):859-67. PubMed ID: 10072683
    [Abstract] [Full Text] [Related]

  • 14. Role of deoxycytidine kinase in the inhibitory activity of 5-substituted 2'-deoxycytidines and cytosine arabinosides on tumor cell growth.
    Balzarini J, De Clercq E.
    Mol Pharmacol; 1983 Jan 11; 23(1):175-81. PubMed ID: 6306422
    [Abstract] [Full Text] [Related]

  • 15. Antiviral, antimetabolic, and cytotoxic activities of 5-substituted 2'-deoxycytidines.
    De Clercq E, Balzarini J, Descamps J, Huang GF, Torrence PF, Bergstrom DE, Jones AS, Serafinowski P, Verhelst G, Walker RT.
    Mol Pharmacol; 1982 Jan 11; 21(1):217-23. PubMed ID: 7132959
    [Abstract] [Full Text] [Related]

  • 16. Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.
    Uckun FM, Pendergrass S, Qazi S, Samuel P, Venkatachalam TK.
    Eur J Med Chem; 2004 Mar 11; 39(3):225-34. PubMed ID: 15051170
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and structure-activity relationships of 2',3'-dideoxypurine nucleosides as potential antiretroviral agents.
    Kojima E, Shirasaka T, Machida M, Yoshioka H, Murakami K, Mitsuya H.
    Nucleic Acids Symp Ser; 1991 Mar 11; (25):91-2. PubMed ID: 1668777
    [Abstract] [Full Text] [Related]

  • 18. Phosphodiester amidates of allenic nucleoside analogues: anti-HIV activity and possible mechanism of action.
    Winter H, Maeda Y, Mitsuya H, Zemlicka J.
    J Med Chem; 1996 Aug 16; 39(17):3300-6. PubMed ID: 8765513
    [Abstract] [Full Text] [Related]

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