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Journal Abstract Search

184 related items for PubMed ID: 36560772

  • 1. Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors.
    Nasr T, Aboshanab AM, Mpekoulis G, Drakopoulos A, Vassilaki N, Zoidis G, Abouzid KAM, Zaghary W.
    Viruses; 2022 Dec 12; 14(12):. PubMed ID: 36560772
    [Abstract] [Full Text] [Related]

  • 2. Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.
    Jin G, Lee S, Choi M, Son S, Kim GW, Oh JW, Lee C, Lee K.
    Eur J Med Chem; 2014 Mar 21; 75():413-25. PubMed ID: 24561671
    [Abstract] [Full Text] [Related]

  • 3. Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking.
    Wei Y, Li J, Qing J, Huang M, Wu M, Gao F, Li D, Hong Z, Kong L, Huang W, Lin J.
    PLoS One; 2016 Mar 21; 11(2):e0148181. PubMed ID: 26845440
    [Abstract] [Full Text] [Related]

  • 4. Development of intergenotypic chimeric replicons to determine the broad-spectrum antiviral activities of hepatitis C virus polymerase inhibitors.
    Herlihy KJ, Graham JP, Kumpf R, Patick AK, Duggal R, Shi ST.
    Antimicrob Agents Chemother; 2008 Oct 21; 52(10):3523-31. PubMed ID: 18694956
    [Abstract] [Full Text] [Related]

  • 5. Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.
    Beaulieu PL, Bousquet Y, Gauthier J, Gillard J, Marquis M, McKercher G, Pellerin C, Valois S, Kukolj G.
    J Med Chem; 2004 Dec 30; 47(27):6884-92. PubMed ID: 15615537
    [Abstract] [Full Text] [Related]

  • 6. Anti-hepatitis-C virus activity and QSAR study of certain thiazolidinone and thiazolotriazine derivatives as potential NS5B polymerase inhibitors.
    Hassan GS, Georgey HH, Mohammed EZ, Omar FA.
    Eur J Med Chem; 2019 Dec 15; 184():111747. PubMed ID: 31604164
    [Abstract] [Full Text] [Related]

  • 7. Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: discovery of a quinazolinone chemotype.
    Beaulieu PL, Coulombe R, Duan J, Fazal G, Godbout C, Hucke O, Jakalian A, Joly MA, Lepage O, Llinàs-Brunet M, Naud J, Poirier M, Rioux N, Thavonekham B, Kukolj G, Stammers TA.
    Bioorg Med Chem Lett; 2013 Jul 15; 23(14):4132-40. PubMed ID: 23768906
    [Abstract] [Full Text] [Related]

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  • 9. Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives.
    Rawal RK, Katti SB, Kaushik-Basu N, Arora P, Pan Z.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6110-4. PubMed ID: 18947995
    [Abstract] [Full Text] [Related]

  • 10. Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency.
    Cheng Y, Shen J, Peng RZ, Wang GF, Zuo JP, Long YQ.
    Bioorg Med Chem Lett; 2016 Jun 15; 26(12):2900-2906. PubMed ID: 27133482
    [Abstract] [Full Text] [Related]

  • 11. The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
    Manfroni G, Cannalire R, Barreca ML, Kaushik-Basu N, Leyssen P, Winquist J, Iraci N, Manvar D, Paeshuyse J, Guhamazumder R, Basu A, Sabatini S, Tabarrini O, Danielson UH, Neyts J, Cecchetti V.
    J Med Chem; 2014 Mar 13; 57(5):1952-63. PubMed ID: 24131104
    [Abstract] [Full Text] [Related]

  • 12. Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay.
    Ludmerer SW, Graham DJ, Boots E, Murray EM, Simcoe A, Markel EJ, Grobler JA, Flores OA, Olsen DB, Hazuda DJ, LaFemina RL.
    Antimicrob Agents Chemother; 2005 May 13; 49(5):2059-69. PubMed ID: 15855532
    [Abstract] [Full Text] [Related]

  • 13. Discovery of N-arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide derivatives as HCV NS5B polymerase inhibitors.
    Deore RR, Chen GS, Chang PT, Chern TR, Lai SY, Chuang MH, Lin JH, Kung FL, Chen CS, Chiou CT, Chern JW.
    ChemMedChem; 2012 May 13; 7(5):850-60. PubMed ID: 22383290
    [Abstract] [Full Text] [Related]

  • 14. Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.
    Ding Y, Girardet JL, Smith KL, Larson G, Prigaro B, Wu JZ, Yao N.
    Bioorg Chem; 2006 Feb 13; 34(1):26-38. PubMed ID: 16360193
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.
    Liu M, Xu Q, Guo S, Zuo R, Hong Y, Luo Y, Li Y, Gong P, Liu Y.
    Bioorg Med Chem; 2018 May 15; 26(9):2621-2631. PubMed ID: 29681484
    [Abstract] [Full Text] [Related]

  • 16. Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication.
    Barreca ML, Manfroni G, Leyssen P, Winquist J, Kaushik-Basu N, Paeshuyse J, Krishnan R, Iraci N, Sabatini S, Tabarrini O, Basu A, Danielson UH, Neyts J, Cecchetti V.
    J Med Chem; 2013 Mar 28; 56(6):2270-82. PubMed ID: 23409936
    [Abstract] [Full Text] [Related]

  • 17. The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus.
    Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z.
    Bioorg Med Chem; 2012 Jan 01; 20(1):467-79. PubMed ID: 22100256
    [Abstract] [Full Text] [Related]

  • 18. New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors.
    Manfroni G, Manvar D, Barreca ML, Kaushik-Basu N, Leyssen P, Paeshuyse J, Cannalire R, Iraci N, Basu A, Chudaev M, Zamperini C, Dreassi E, Sabatini S, Tabarrini O, Neyts J, Cecchetti V.
    J Med Chem; 2014 Apr 24; 57(8):3247-62. PubMed ID: 24654886
    [Abstract] [Full Text] [Related]

  • 19. In vitro characterization of GSK2485852, a novel hepatitis C virus polymerase inhibitor.
    Voitenleitner C, Crosby R, Walker J, Remlinger K, Vamathevan J, Wang A, You S, Johnson J, Woldu E, Van Horn S, Horton J, Creech K, Shotwell JB, Hong Z, Hamatake R.
    Antimicrob Agents Chemother; 2013 Nov 24; 57(11):5216-24. PubMed ID: 23939896
    [Abstract] [Full Text] [Related]

  • 20. PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
    Lam AM, Murakami E, Espiritu C, Steuer HM, Niu C, Keilman M, Bao H, Zennou V, Bourne N, Julander JG, Morrey JD, Smee DF, Frick DN, Heck JA, Wang P, Nagarathnam D, Ross BS, Sofia MJ, Otto MJ, Furman PA.
    Antimicrob Agents Chemother; 2010 Aug 24; 54(8):3187-96. PubMed ID: 20516278
    [Abstract] [Full Text] [Related]

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