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137 related items for PubMed ID: 36592951

  • 1. In Vivo Mechanism of Action of Sodium Caprate for Improving the Intestinal Absorption of a GLP1/GIP Coagonist Peptide.
    Tran H, Aihara E, Mohammed FA, Qu H, Riley A, Su Y, Lai X, Huang S, Aburub A, Chen JJH, Vitale OH, Lao Y, Estwick S, Qi Z, ElSayed MEH.
    Mol Pharm; 2023 Feb 06; 20(2):929-941. PubMed ID: 36592951
    [Abstract] [Full Text] [Related]

  • 2. Development and evaluation of C10 and SNAC erodible tablets for gastric delivery of a GIP/GLP1 peptide in monkeys.
    Tran H, Dogra M, Huang S, Aihara E, ElSayed M, Aburub A.
    Int J Pharm; 2024 Jan 25; 650():123680. PubMed ID: 38070657
    [Abstract] [Full Text] [Related]

  • 3. Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat.
    Berg S, Kärrberg L, Suljovic D, Seeliger F, Söderberg M, Perez-Alcazar M, Van Zuydam N, Abrahamsson B, Hugerth AM, Davies N, Bergström CAS.
    Mol Pharm; 2022 Jan 03; 19(1):200-212. PubMed ID: 34928160
    [Abstract] [Full Text] [Related]

  • 4. Identification of a Multi-Component Formulation for Intestinal Delivery of a GLP-1/Glucagon Co-agonist Peptide.
    Tran H, Patel PJ, Aburub A, Sperry A, Estwick S, ElSayed MEH, -Mannan AD.
    Pharm Res; 2022 Oct 03; 39(10):2555-2567. PubMed ID: 36050547
    [Abstract] [Full Text] [Related]

  • 5. Comparison of the effects of the intestinal permeation enhancers, SNAC and sodium caprate (C10): Isolated rat intestinal mucosae and sacs.
    Twarog C, McCartney F, Harrison SM, Illel B, Fattal E, Brayden DJ.
    Eur J Pharm Sci; 2021 Mar 01; 158():105685. PubMed ID: 33359131
    [Abstract] [Full Text] [Related]

  • 6. A head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10).
    Twarog C, Liu K, O'Brien PJ, Dawson KA, Fattal E, Illel B, Brayden DJ.
    Eur J Pharm Biopharm; 2020 Jul 01; 152():95-107. PubMed ID: 32387703
    [Abstract] [Full Text] [Related]

  • 7. Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition.
    Gleeson JP, Frías JM, Ryan SM, Brayden DJ.
    Eur J Pharm Biopharm; 2018 Jul 01; 128():179-187. PubMed ID: 29684535
    [Abstract] [Full Text] [Related]

  • 8. In vitro and in vivo evaluation of effects of sodium caprate on enteral peptide absorption and on mucosal morphology.
    Chao AC, Nguyen JV, Broughall M, Griffin A, Fix JA, Daddona PE.
    Int J Pharm; 1999 Nov 25; 191(1):15-24. PubMed ID: 10556736
    [Abstract] [Full Text] [Related]

  • 9. Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model.
    Berg S, Suljovic D, Kärrberg L, Englund M, Bönisch H, Karlberg I, Van Zuydam N, Abrahamsson B, Hugerth AM, Davies N, Bergström CAS.
    Mol Pharm; 2022 Jul 04; 19(7):2564-2572. PubMed ID: 35642793
    [Abstract] [Full Text] [Related]

  • 10. Enhancing Intestinal Absorption of a Model Macromolecule via the Paracellular Pathway using E-Cadherin Peptides.
    Dening TJ, Siahaan TJ, Hageman MJ.
    J Pharm Sci; 2021 May 04; 110(5):2139-2148. PubMed ID: 33359310
    [Abstract] [Full Text] [Related]

  • 11. Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol.
    Brayden DJ, Maher S, Bahar B, Walsh E.
    Eur J Pharm Biopharm; 2015 Aug 04; 94():194-206. PubMed ID: 26026287
    [Abstract] [Full Text] [Related]

  • 12. Characterization of the physicochemical interactions between exenatide and two intestinal permeation enhancers: Sodium caprate (C10) and salcaprozate sodium (SNAC).
    Twarog C, Fattal E, Noiray M, Illel B, Brayden DJ, Taverna M, Hillaireau H.
    Int J Pharm; 2022 Oct 15; 626():122131. PubMed ID: 36028084
    [Abstract] [Full Text] [Related]

  • 13. Efficacious intestinal permeation enhancement induced by the sodium salt of 10-undecylenic acid, a medium chain fatty acid derivative.
    Brayden DJ, Walsh E.
    AAPS J; 2014 Sep 15; 16(5):1064-76. PubMed ID: 24961919
    [Abstract] [Full Text] [Related]

  • 14. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C10).
    Twarog C, Fattah S, Heade J, Maher S, Fattal E, Brayden DJ.
    Pharmaceutics; 2019 Feb 13; 11(2):. PubMed ID: 30781867
    [Abstract] [Full Text] [Related]

  • 15. Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: assessment of molecular weight dependence and demonstration of transport routes.
    Lindmark T, Schipper N, Lazorová L, de Boer AG, Artursson P.
    J Drug Target; 1998 Feb 13; 5(3):215-23. PubMed ID: 9606011
    [Abstract] [Full Text] [Related]

  • 16. LabrafacTM MC60 is an efficacious intestinal permeation enhancer for macromolecules: Comparisons with Labrasol® ALF in ex vivo and in vivo rat studies.
    McCartney F, Caisse P, Dumont C, Brayden DJ.
    Int J Pharm; 2024 Aug 15; 661():124353. PubMed ID: 38909926
    [Abstract] [Full Text] [Related]

  • 17. Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate.
    Wang X, Maher S, Brayden DJ.
    Ther Deliv; 2010 Jul 15; 1(1):75-82. PubMed ID: 22816121
    [Abstract] [Full Text] [Related]

  • 18. Labrasol® and Salts of Medium-Chain Fatty Acids Can Be Combined in Low Concentrations to Increase the Permeability of a Macromolecule Marker Across Isolated Rat Intestinal Mucosae.
    Heade J, Maher S, Bleiel SB, Brayden DJ.
    J Pharm Sci; 2018 Jun 15; 107(6):1648-1655. PubMed ID: 29462634
    [Abstract] [Full Text] [Related]

  • 19. Propylene Glycol Caprylate as a Novel Potential Absorption Enhancer for Improving the Intestinal Absorption of Insulin: Efficacy, Safety, and Absorption-Enhancing Mechanisms.
    Ukai H, Kawagoe A, Sato E, Morishita M, Katsumi H, Yamamoto A.
    J Pharm Sci; 2020 Apr 15; 109(4):1483-1492. PubMed ID: 31884013
    [Abstract] [Full Text] [Related]

  • 20. Reversible increase in tight junction permeability to macromolecules in rat ileal mucosa in vitro by sodium caprate, a constituent of milk fat.
    Söderholm JD, Oman H, Blomquist L, Veen J, Lindmark T, Olaison G.
    Dig Dis Sci; 1998 Jul 15; 43(7):1547-52. PubMed ID: 9690393
    [Abstract] [Full Text] [Related]

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