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PUBMED FOR HANDHELDS

Journal Abstract Search


180 related items for PubMed ID: 36615435

  • 1. Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.
    Godyń J, Zaręba P, Stary D, Kaleta M, Kuder KJ, Latacz G, Mogilski S, Reiner-Link D, Frank A, Doroz-Płonka A, Olejarz-Maciej A, Sudoł-Tałaj S, Nolte T, Handzlik J, Stark H, Więckowska A, Malawska B, Kieć-Kononowicz K, Łażewska D, Bajda M.
    Molecules; 2022 Dec 28; 28(1):. PubMed ID: 36615435
    [Abstract] [Full Text] [Related]

  • 2. Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
    Godyń J, Zaręba P, Łażewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M, Doroz-Płonka A, Lubelska A, Honkisz-Orzechowska E, Olejarz-Maciej A, Handzlik J, Stark H, Kieć-Kononowicz K, Malawska B, Bajda M.
    Bioorg Chem; 2021 Sep 28; 114():105129. PubMed ID: 34217977
    [Abstract] [Full Text] [Related]

  • 3. Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease.
    Łażewska D, Bajda M, Kaleta M, Zaręba P, Doroz-Płonka A, Siwek A, Alachkar A, Mogilski S, Saad A, Kuder K, Olejarz-Maciej A, Godyń J, Stary D, Sudoł S, Więcek M, Latacz G, Walczak M, Handzlik J, Sadek B, Malawska B, Kieć-Kononowicz K.
    Eur J Med Chem; 2020 Dec 01; 207():112743. PubMed ID: 32882609
    [Abstract] [Full Text] [Related]

  • 4. Biphenylalkoxyamine Derivatives-Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.
    Łażewska D, Zaręba P, Godyń J, Doroz-Płonka A, Frank A, Reiner-Link D, Bajda M, Stary D, Mogilski S, Olejarz-Maciej A, Kaleta M, Stark H, Malawska B, Kieć-Kononowicz K.
    Molecules; 2021 Jun 11; 26(12):. PubMed ID: 34208297
    [Abstract] [Full Text] [Related]

  • 5. Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives.
    Jończyk J, Lodarski K, Staszewski M, Godyń J, Zaręba P, Soukup O, Janockova J, Korabecny J, Sałat K, Malikowska-Racia N, Hebda M, Szałaj N, Filipek B, Walczyński K, Malawska B, Bajda M.
    Bioorg Chem; 2019 Sep 11; 90():103084. PubMed ID: 31271942
    [Abstract] [Full Text] [Related]

  • 6. 4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H3 Receptors and Cholinesterases.
    Michalska B, Dzięgielewski M, Godyń J, Werner T, Bajda M, Karcz T, Szczepańska K, Stark H, Więckowska A, Walczyński K, Staszewski M.
    ACS Chem Neurosci; 2024 Mar 20; 15(6):1206-1218. PubMed ID: 38440987
    [Abstract] [Full Text] [Related]

  • 7. Multitargeting Histamine H3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives.
    Łażewska D, Kaleta M, Zaręba P, Godyń J, Dubiel M, Honkisz-Orzechowska E, Doroz-Płonka A, Więckowska A, Stark H, Kieć-Kononowicz K.
    Molecules; 2023 Mar 03; 28(5):. PubMed ID: 36903593
    [Abstract] [Full Text] [Related]

  • 8. Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands.
    Bajda M, Łażewska D, Godyń J, Zaręba P, Kuder K, Hagenow S, Łątka K, Stawarska E, Stark H, Kieć-Kononowicz K, Malawska B.
    Eur J Med Chem; 2020 Jan 01; 185():111785. PubMed ID: 31669851
    [Abstract] [Full Text] [Related]

  • 9. In silico and in vitro studies of two non-imidazole multiple targeting agents at histamine H3 receptors and cholinesterase enzymes.
    Ghamari N, Dastmalchi S, Zarei O, Arias-Montaño JA, Reiner D, Ustun-Alkan F, Stark H, Hamzeh-Mivehroud M.
    Chem Biol Drug Des; 2020 Feb 01; 95(2):279-290. PubMed ID: 31661597
    [Abstract] [Full Text] [Related]

  • 10. Scutellarein derivatives with histamine H3 receptor antagonism and cholinesterase inhibitory potency as multi target-directed ligands for possible Alzheimer's disease therapy.
    Chen J, He Z, Luo K, Luo Q, Wang Y, Liu T, Li L, Dai Z, Yang S, Li Y, Zhao Y, Tang L, Fu X.
    Bioorg Chem; 2024 Oct 01; 151():107704. PubMed ID: 39126870
    [Abstract] [Full Text] [Related]

  • 11. Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease.
    Hafez DE, Dubiel M, La Spada G, Catto M, Reiner-Link D, Syu YT, Abdel-Halim M, Hwang TL, Stark H, Abadi AH.
    J Enzyme Inhib Med Chem; 2023 Dec 01; 38(1):2175821. PubMed ID: 36789662
    [Abstract] [Full Text] [Related]

  • 12. Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands.
    Łażewska D, Jończyk J, Bajda M, Szałaj N, Więckowska A, Panek D, Moore C, Kuder K, Malawska B, Kieć-Kononowicz K.
    Bioorg Med Chem Lett; 2016 Aug 15; 26(16):4140-5. PubMed ID: 27445168
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease.
    Wang D, Hu M, Li X, Zhang D, Chen C, Fu J, Shao S, Shi G, Zhou Y, Wu S, Zhang T.
    Eur J Med Chem; 2019 Apr 15; 168():207-220. PubMed ID: 30822710
    [Abstract] [Full Text] [Related]

  • 14. Indoloquinoxaline derivatives as promising multi-functional anti-Alzheimer agents.
    Kanhed AM, Patel DV, Patel NR, Sinha A, Thakor PS, Patel KB, Prajapati NK, Patel KV, Yadav MR.
    J Biomol Struct Dyn; 2022 Apr 15; 40(6):2498-2515. PubMed ID: 33111617
    [Abstract] [Full Text] [Related]

  • 15. Novel naphthyloxy derivatives - Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation.
    Łażewska D, Kaleta M, Hagenow S, Mogilski S, Latacz G, Karcz T, Lubelska A, Honkisz E, Handzlik J, Reiner D, Satała G, Filipek B, Stark H, Kieć-Kononowicz K.
    Bioorg Med Chem; 2018 May 15; 26(9):2573-2585. PubMed ID: 29681486
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of the histamine H3 receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies.
    Lopes FB, Aranha CMSQ, Corrêa MF, Fernandes GAB, Okamoto DN, Simões LPM, Junior NMN, Fernandes JPS.
    Chem Biol Drug Des; 2022 Nov 15; 100(5):722-729. PubMed ID: 36050829
    [Abstract] [Full Text] [Related]

  • 17. New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition.
    Malek R, Arribas RL, Palomino-Antolin A, Totoson P, Demougeot C, Kobrlova T, Soukup O, Iriepa I, Moraleda I, Diez-Iriepa D, Godyń J, Panek D, Malawska B, Głuch-Lutwin M, Mordyl B, Siwek A, Chabchoub F, Marco-Contelles J, Kiec-Kononowicz K, Egea J, de Los Ríos C, Ismaili L.
    J Med Chem; 2019 Dec 26; 62(24):11416-11422. PubMed ID: 31724859
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
    Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K.
    Eur J Med Chem; 2018 May 25; 152():223-234. PubMed ID: 29723785
    [Abstract] [Full Text] [Related]

  • 19. Histamine H3 receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.
    Lopes FB, Aranha CMSQ, Fernandes JPS.
    Chem Biol Drug Des; 2021 Aug 25; 98(2):212-225. PubMed ID: 33991182
    [Abstract] [Full Text] [Related]

  • 20. Identification of N-phenyl-3-methoxy-4-pyridinones as orally bioavailable H3 receptor antagonists and β-amyloid aggregation inhibitors for the treatment of Alzheimer's disease.
    Zhang M, Tang L, Jiang L, Wei J, Hu Y, Sheng R.
    Eur J Med Chem; 2021 Feb 15; 212():113096. PubMed ID: 33395621
    [Abstract] [Full Text] [Related]


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