These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

224 related items for PubMed ID: 36621138

  • 1. Discovery and biological evaluation of 4,6-pyrimidine analogues with potential anticancer agents as novel colchicine binding site inhibitors.
    Zhang J, Tan L, Wu C, Li Y, Chen H, Liu Y, Wang Y.
    Eur J Med Chem; 2023 Feb 15; 248():115085. PubMed ID: 36621138
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 3. Discovery and mechanistic insights into thieno[3,2-d]pyrimidine and heterocyclic fused pyrimidines inhibitors targeting tubulin for cancer therapy.
    Wu C, Zhang L, Zhou Z, Tan L, Wang Z, Guo C, Wang Y.
    Eur J Med Chem; 2024 Oct 05; 276():116649. PubMed ID: 38972078
    [Abstract] [Full Text] [Related]

  • 4. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 05; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 5. Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors.
    Li N, Guan Q, Hong Y, Zhang B, Li M, Li X, Li B, Wu L, Zhang W.
    Eur J Med Chem; 2023 Aug 05; 256():115402. PubMed ID: 37182330
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of structurally diverse 6-aryl-3-aroyl-indole analogues as inhibitors of tubulin polymerization.
    Ren W, Deng Y, Ward JD, Vairin R, Bai R, Wanniarachchi HI, Hamal KB, Tankoano PE, Tamminga CS, Bueno LMA, Hamel E, Mason RP, Trawick ML, Pinney KG.
    Eur J Med Chem; 2024 Jan 05; 263():115794. PubMed ID: 37984295
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and biological evaluation of benz-fused five-membered heterocyclic compounds as tubulin polymerization inhibitors with anticancer activities.
    Komuraiah B, Ren Y, Xue M, Cheng B, Liu J, Liu Y, Chen J.
    Chem Biol Drug Des; 2021 May 05; 97(5):1109-1116. PubMed ID: 33638903
    [Abstract] [Full Text] [Related]

  • 8. Discovery of Novel N-Heterocyclic-Fused Deoxypodophyllotoxin Analogues as Tubulin Polymerization Inhibitors Targeting the Colchicine-Binding Site for Cancer Treatment.
    Leng J, Zhao Y, Sheng P, Xia Y, Chen T, Zhao S, Xie S, Yan X, Wang X, Yin Y, Kong L.
    J Med Chem; 2022 Dec 22; 65(24):16774-16800. PubMed ID: 36471625
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of (2-(phenylamino)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone analogues as potent anti-tubulin polymerization agents.
    Tian C, Chen X, Zhang Z, Wang X, Liu J.
    Eur J Med Chem; 2019 Dec 01; 183():111679. PubMed ID: 31541870
    [Abstract] [Full Text] [Related]

  • 10. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 11. Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities.
    Song J, Wang SY, Wang X, Jia MQ, Tian XY, Fu XJ, Jin CY, Zhang SY.
    Bioorg Chem; 2023 Aug 01; 137():106580. PubMed ID: 37149948
    [Abstract] [Full Text] [Related]

  • 12. Discovery of novel thiophene[3,2-d]pyrimidine-based tubulin inhibitors with enhanced antitumor efficacy for combined use with anti-pd-l1 immunotherapy in melanoma.
    Xu C, Wu C, Li L, Zhao H, Liu J, Peng X, Wang Y, Chen J.
    Eur J Med Chem; 2024 Nov 05; 277():116791. PubMed ID: 39197251
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 14. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
    Cheng B, Zhu G, Meng L, Wu G, Chen Q, Ma S.
    Eur J Med Chem; 2022 Jan 15; 228():113930. PubMed ID: 34794817
    [Abstract] [Full Text] [Related]

  • 15. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 15; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 16. Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X-ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site.
    Tan L, Wu C, Zhang J, Yu Q, Wang X, Zhang L, Ge M, Wang Z, Ouyang L, Wang Y.
    J Med Chem; 2023 Mar 09; 66(5):3588-3620. PubMed ID: 36802449
    [Abstract] [Full Text] [Related]

  • 17. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
    Lin S, Du T, Zhang J, Wu D, Tian H, Zhang K, Jiang L, Lu D, Sheng L, Li Y, Ji M, Chen X, Xu H.
    J Med Chem; 2022 Dec 22; 65(24):16372-16391. PubMed ID: 36511661
    [Abstract] [Full Text] [Related]

  • 18. Discovery of polymethoxyphenyl-pyridines bearing amino side chains as tubulin colchicine-binding site inhibitors.
    Li X, Wu H, Feng KW, Xu J, Wu S, Zhou ZZ, Li XF.
    Bioorg Med Chem; 2022 Nov 01; 73():117007. PubMed ID: 36150341
    [Abstract] [Full Text] [Related]

  • 19. Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities.
    Song J, Guan YF, Liu WB, Song CH, Tian XY, Zhu T, Fu XJ, Qi YQ, Zhang SY.
    Eur J Med Chem; 2022 Aug 05; 238():114467. PubMed ID: 35605363
    [Abstract] [Full Text] [Related]

  • 20. An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors.
    Weng H, Li J, Zhu H, Carver Wong KF, Zhu Z, Xu J.
    Future Med Chem; 2023 Jan 05; 15(1):73-95. PubMed ID: 36756851
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 12.