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Journal Abstract Search

173 related items for PubMed ID: 36713721

  • 1. Functional Impact of a Cancer-Related Variant in Human Δ1-Pyrroline-5-Carboxylate Reductase 1.
    Daudu OI, Meeks KR, Zhang L, Seravalli J, Tanner JJ, Becker DF.
    ACS Omega; 2023 Jan 24; 8(3):3509-3519. PubMed ID: 36713721
    [Abstract] [Full Text] [Related]

  • 2. Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.
    Christensen EM, Patel SM, Korasick DA, Campbell AC, Krause KL, Becker DF, Tanner JJ.
    J Biol Chem; 2017 Apr 28; 292(17):7233-7243. PubMed ID: 28258219
    [Abstract] [Full Text] [Related]

  • 3. Disease variants of human Δ1-pyrroline-5-carboxylate reductase 2 (PYCR2).
    Patel SM, Seravalli J, Liang X, Tanner JJ, Becker DF.
    Arch Biochem Biophys; 2021 May 30; 703():108852. PubMed ID: 33771508
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  • 5. In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
    Christensen EM, Bogner AN, Vandekeere A, Tam GS, Patel SM, Becker DF, Fendt SM, Tanner JJ.
    J Biol Chem; 2020 Dec 25; 295(52):18316-18327. PubMed ID: 33109600
    [Abstract] [Full Text] [Related]

  • 6. Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target.
    Bogner AN, Stiers KM, Tanner JJ.
    Amino Acids; 2021 Dec 25; 53(12):1817-1834. PubMed ID: 34003320
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  • 8. Isozymes of P5C reductase (PYCR) in human diseases: focus on cancer.
    Hu CA.
    Amino Acids; 2021 Dec 25; 53(12):1835-1840. PubMed ID: 34291342
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  • 10. Kinetics of human pyrroline-5-carboxylate reductase in L-thioproline metabolism.
    Patel SM, Seravalli J, Stiers KM, Tanner JJ, Becker DF.
    Amino Acids; 2021 Dec 25; 53(12):1863-1874. PubMed ID: 34792644
    [Abstract] [Full Text] [Related]

  • 11. PYCR in Kidney Renal Papillary Cell Carcinoma: Expression, Prognosis, Gene Regulation Network, and Regulation Targets.
    Shao Z, Lu L, Cui Y, Deng L, Xu Q, Liang Q, Lu X, Zhang J, Chen J, Situ Y.
    Front Biosci (Landmark Ed); 2022 Dec 28; 27(12):336. PubMed ID: 36624948
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  • 13. Deciphering the Effects of the PYCR Family on Cell Function, Prognostic Value, Immune Infiltration in ccRCC and Pan-Cancer.
    Chen H, Chen Q, Chen J, Mao Y, Duan L, Ye D, Cheng W, Chen J, Gao X, Lin R, Lin W, Zhang M, Qi Y.
    Int J Mol Sci; 2024 Jul 25; 25(15):. PubMed ID: 39125668
    [Abstract] [Full Text] [Related]

  • 14. The Proline Cycle As a Potential Cancer Therapy Target.
    Tanner JJ, Fendt SM, Becker DF.
    Biochemistry; 2018 Jun 26; 57(25):3433-3444. PubMed ID: 29648801
    [Abstract] [Full Text] [Related]

  • 15. Genetic analysis of Pycr1 and Pycr2 in mice.
    Stum MG, Tadenev ALD, Seburn KL, Miers KE, Poon PP, McMaster CR, Robinson C, Kane C, Silva KA, Cliften PF, Sundberg JP, Reinholdt LG, John SWM, Burgess RW.
    Genetics; 2021 May 17; 218(1):. PubMed ID: 33734376
    [Abstract] [Full Text] [Related]

  • 16. Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers.
    Ding J, Kuo ML, Su L, Xue L, Luh F, Zhang H, Wang J, Lin TG, Zhang K, Chu P, Zheng S, Liu X, Yen Y.
    Carcinogenesis; 2017 May 01; 38(5):519-531. PubMed ID: 28379297
    [Abstract] [Full Text] [Related]

  • 17. SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism.
    Chen S, Yang X, Yu M, Wang Z, Liu B, Liu M, Liu L, Ren M, Qi H, Zou J, Vucenik I, Zhu WG, Luo J.
    Neoplasia; 2019 Jul 01; 21(7):665-675. PubMed ID: 31108370
    [Abstract] [Full Text] [Related]

  • 18. Phenyl-substituted aminomethylene-bisphosphonates inhibit human P5C reductase and show antiproliferative activity against proline-hyperproducing tumour cells.
    Forlani G, Sabbioni G, Ragno D, Petrollino D, Borgatti M.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):1248-1257. PubMed ID: 34107832
    [Abstract] [Full Text] [Related]

  • 19. Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis.
    Oudaert I, Satilmis H, Vlummens P, De Brouwer W, Maes A, Hose D, De Bruyne E, Ghesquière B, Vanderkerken K, De Veirman K, Menu E.
    J Exp Clin Cancer Res; 2022 Feb 01; 41(1):45. PubMed ID: 35105345
    [Abstract] [Full Text] [Related]

  • 20. Functional specialization in proline biosynthesis of melanoma.
    De Ingeniis J, Ratnikov B, Richardson AD, Scott DA, Aza-Blanc P, De SK, Kazanov M, Pellecchia M, Ronai Z, Osterman AL, Smith JW.
    PLoS One; 2012 Feb 01; 7(9):e45190. PubMed ID: 23024808
    [Abstract] [Full Text] [Related]

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