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Journal Abstract Search

191 related items for PubMed ID: 36834937

  • 1. Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis.
    Hu Q, Lai J, Chen H, Cai Y, Yue Z, Lin H, Sun L.
    Int J Mol Sci; 2023 Feb 09; 24(4):. PubMed ID: 36834937
    [Abstract] [Full Text] [Related]

  • 2. Regulation of the RhoA exchange factor GEF-H1 by profibrotic stimuli through a positive feedback loop involving RhoA, MRTF, and Sp1.
    Venugopal S, Dan Q, Sri Theivakadadcham VS, Wu B, Kofler M, Layne MD, Connelly KA, Rzepka MF, Friedberg MK, Kapus A, Szászi K.
    Am J Physiol Cell Physiol; 2024 Aug 01; 327(2):C387-C402. PubMed ID: 38912734
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of smad7 inhibits the TGF-β/Smad signaling pathway and EMT in NPHP1-defective MDCK cells.
    Wu X, Wang H, Chen H, Lin H, Li M, Yue Z, Sun L.
    Biochem Biophys Res Commun; 2021 Dec 10; 582():57-63. PubMed ID: 34689106
    [Abstract] [Full Text] [Related]

  • 4. Claudin-2 suppresses GEF-H1, RHOA, and MRTF, thereby impacting proliferation and profibrotic phenotype of tubular cells.
    Dan Q, Shi Y, Rabani R, Venugopal S, Xiao J, Anwer S, Ding M, Speight P, Pan W, Alexander RT, Kapus A, Szászi K.
    J Biol Chem; 2019 Oct 18; 294(42):15446-15465. PubMed ID: 31481470
    [Abstract] [Full Text] [Related]

  • 5. Increased expression of GEF-H1 promotes colon cancer progression by RhoA signaling.
    Cao J, Yang T, Tang D, Zhou F, Qian Y, Zou X.
    Pathol Res Pract; 2019 May 18; 215(5):1012-1019. PubMed ID: 30846413
    [Abstract] [Full Text] [Related]

  • 6. Role of guanine nucleotide exchange factor-H1 in complement-mediated RhoA activation in glomerular epithelial cells.
    Mouawad F, Aoudjit L, Jiang R, Szaszi K, Takano T.
    J Biol Chem; 2014 Feb 14; 289(7):4206-18. PubMed ID: 24356971
    [Abstract] [Full Text] [Related]

  • 7. GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling.
    Cheng IK, Tsang BC, Lai KP, Ching AK, Chan AW, To KF, Lai PB, Wong N.
    J Pathol; 2012 Dec 14; 228(4):575-85. PubMed ID: 22847784
    [Abstract] [Full Text] [Related]

  • 8. Heparin inhibits pulmonary artery smooth muscle cell proliferation through guanine nucleotide exchange factor-H1/RhoA/Rho kinase/p27.
    Yu L, Quinn DA, Garg HG, Hales CA.
    Am J Respir Cell Mol Biol; 2011 Apr 14; 44(4):524-30. PubMed ID: 20558775
    [Abstract] [Full Text] [Related]

  • 9. The epidermal growth factor receptor mediates tumor necrosis factor-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular epithelium.
    Kakiashvili E, Dan Q, Vandermeer M, Zhang Y, Waheed F, Pham M, Szászi K.
    J Biol Chem; 2011 Mar 18; 286(11):9268-79. PubMed ID: 21212278
    [Abstract] [Full Text] [Related]

  • 10. Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge.
    Nalbant P, Chang YC, Birkenfeld J, Chang ZF, Bokoch GM.
    Mol Biol Cell; 2009 Sep 18; 20(18):4070-82. PubMed ID: 19625450
    [Abstract] [Full Text] [Related]

  • 11. The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration.
    Tsapara A, Luthert P, Greenwood J, Hill CS, Matter K, Balda MS.
    Mol Biol Cell; 2010 Mar 15; 21(6):860-70. PubMed ID: 20089843
    [Abstract] [Full Text] [Related]

  • 12. The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets.
    Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A.
    J Thromb Haemost; 2020 Nov 15; 18(11):3002-3012. PubMed ID: 32692911
    [Abstract] [Full Text] [Related]

  • 13. Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.
    Waheed F, Dan Q, Amoozadeh Y, Zhang Y, Tanimura S, Speight P, Kapus A, Szászi K.
    Mol Biol Cell; 2013 Apr 15; 24(7):1068-82. PubMed ID: 23389627
    [Abstract] [Full Text] [Related]

  • 14. BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation.
    Pan M, Chew TW, Wong DCP, Xiao J, Ong HT, Chin JFL, Low BC.
    Sci Adv; 2020 Jul 15; 6(31):eaaz1534. PubMed ID: 32789168
    [Abstract] [Full Text] [Related]

  • 15. Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
    Li Y, Xu W, Makova S, Brueckner M, Sun Z.
    Elife; 2023 Mar 15; 12():. PubMed ID: 36920028
    [Abstract] [Full Text] [Related]

  • 16. S-1-propenylcysteine improves TNF-α-induced vascular endothelial barrier dysfunction by suppressing the GEF-H1/RhoA/Rac pathway.
    Kunimura K, Miki S, Takashima M, Suzuki JI.
    Cell Commun Signal; 2021 Feb 15; 19(1):17. PubMed ID: 33588881
    [Abstract] [Full Text] [Related]

  • 17. GEF-H1/RhoA signaling pathway mediates pro-inflammatory effects of NF-κB on CD40L-induced pulmonary endothelial cells.
    Chang M, Yi L, Zhou Z, Yi X, Chen H, Liang X, Jin R, Huang X.
    Mol Immunol; 2023 May 15; 157():42-52. PubMed ID: 36989839
    [Abstract] [Full Text] [Related]

  • 18. GEF-H1-RhoA signaling pathway mediates LPS-induced NF-κB transactivation and IL-8 synthesis in endothelial cells.
    Guo F, Tang J, Zhou Z, Dou Y, Van Lonkhuyzen D, Gao C, Huan J.
    Mol Immunol; 2012 Feb 15; 50(1-2):98-107. PubMed ID: 22226472
    [Abstract] [Full Text] [Related]

  • 19. GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases.
    Birkenfeld J, Nalbant P, Bohl BP, Pertz O, Hahn KM, Bokoch GM.
    Dev Cell; 2007 May 15; 12(5):699-712. PubMed ID: 17488622
    [Abstract] [Full Text] [Related]

  • 20. Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization.
    Yamahashi Y, Saito Y, Murata-Kamiya N, Hatakeyama M.
    J Biol Chem; 2011 Dec 30; 286(52):44576-84. PubMed ID: 22072711
    [Abstract] [Full Text] [Related]

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