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176 related items for PubMed ID: 36861094
21. The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model. Castillo-Pichardo L, Humphries-Bickley T, De La Parra C, Forestier-Roman I, Martinez-Ferrer M, Hernandez E, Vlaar C, Ferrer-Acosta Y, Washington AV, Cubano LA, Rodriguez-Orengo J, Dharmawardhane S. Transl Oncol; 2014 Oct; 7(5):546-55. PubMed ID: 25389450 [Abstract] [Full Text] [Related]
22. P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils. Damoulakis G, Gambardella L, Rossman KL, Lawson CD, Anderson KE, Fukui Y, Welch HC, Der CJ, Stephens LR, Hawkins PT. J Cell Sci; 2014 Jun 01; 127(Pt 11):2589-600. PubMed ID: 24659802 [Abstract] [Full Text] [Related]
23. Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases. Ren Y, Li R, Zheng Y, Busch H. J Biol Chem; 1998 Dec 25; 273(52):34954-60. PubMed ID: 9857026 [Abstract] [Full Text] [Related]
24. Targeting Rac and Cdc42 GTPases in Cancer. Maldonado MDM, Dharmawardhane S. Cancer Res; 2018 Jun 15; 78(12):3101-3111. PubMed ID: 29858187 [Abstract] [Full Text] [Related]
25. Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant. Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y. J Biol Chem; 2004 Jan 30; 279(5):3777-86. PubMed ID: 14597635 [Abstract] [Full Text] [Related]
26. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. J Clin Invest; 2013 Oct 30; 123(10):4449-63. PubMed ID: 24091327 [Abstract] [Full Text] [Related]
27. Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis. Patel JC, Hall A, Caron E. Mol Biol Cell; 2002 Apr 30; 13(4):1215-26. PubMed ID: 11950933 [Abstract] [Full Text] [Related]
28. Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases. Feng Q, Albeck JG, Cerione RA, Yang W. J Biol Chem; 2002 Feb 15; 277(7):5644-50. PubMed ID: 11741931 [Abstract] [Full Text] [Related]
30. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. Shutes A, Onesto C, Picard V, Leblond B, Schweighoffer F, Der CJ. J Biol Chem; 2007 Dec 07; 282(49):35666-78. PubMed ID: 17932039 [Abstract] [Full Text] [Related]
31. Rac1 is a novel interactor of Drosophila guanine nucleotide exchange factor GEFmeso. Sundaram S. Mol Cell Biochem; 2015 Jun 07; 404(1-2):259-62. PubMed ID: 25753922 [Abstract] [Full Text] [Related]
33. Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis. Monypenny J, Zicha D, Higashida C, Oceguera-Yanez F, Narumiya S, Watanabe N. Mol Cell Biol; 2009 May 07; 29(10):2730-47. PubMed ID: 19273601 [Abstract] [Full Text] [Related]
35. The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer. Crespo GV, Ortiz J, O'Farrill EH, Vlaar CP, Inyushin M, Kucheryavykh Y, Kucheryavykh L. Mol Med; 2023 Jun 14; 29(1):75. PubMed ID: 37316799 [Abstract] [Full Text] [Related]
36. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling. Boissier P, Huynh-Do U. Cell Signal; 2014 Mar 14; 26(3):483-91. PubMed ID: 24308970 [Abstract] [Full Text] [Related]
37. The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance. Demarco RS, Struckhoff EC, Lundquist EA. PLoS Genet; 2012 Mar 14; 8(4):e1002665. PubMed ID: 22570618 [Abstract] [Full Text] [Related]
38. Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer. Borrero-García LD, Del Mar Maldonado M, Medina-Velázquez J, Troche-Torres AL, Velazquez L, Grafals-Ruiz N, Dharmawardhane S. BMC Cancer; 2021 Jun 01; 21(1):652. PubMed ID: 34074257 [Abstract] [Full Text] [Related]
39. Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis. Laurin M, Huber J, Pelletier A, Houalla T, Park M, Fukui Y, Haibe-Kains B, Muller WJ, Côté JF. Proc Natl Acad Sci U S A; 2013 Apr 30; 110(18):7434-9. PubMed ID: 23592719 [Abstract] [Full Text] [Related]
40. Importance of spatial activation of Cdc42 and rac small G proteins by frabin for microspike formation in MDCK cells. Yasuda T, Ohtsuka T, Inoue E, Yokoyama S, Sakisaka T, Kodama A, Takaishi K, Takai Y. Genes Cells; 2000 Jul 30; 5(7):583-91. PubMed ID: 10947844 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]