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151 related items for PubMed ID: 36893894

  • 1. Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
    Coni S, Bordone R, Ivy DM, Yurtsever ZN, Di Magno L, D'Amico R, Cesaro B, Fatica A, Belardinilli F, Bufalieri F, Maroder M, De Smaele E, Di Marcotullio L, Giannini G, Agostinelli E, Canettieri G.
    Cancer Lett; 2023 Apr 10; 559():216120. PubMed ID: 36893894
    [Abstract] [Full Text] [Related]

  • 2. Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
    Coni S, Serrao SM, Yurtsever ZN, Di Magno L, Bordone R, Bertani C, Licursi V, Ianniello Z, Infante P, Moretti M, Petroni M, Guerrieri F, Fatica A, Macone A, De Smaele E, Di Marcotullio L, Giannini G, Maroder M, Agostinelli E, Canettieri G.
    Cell Death Dis; 2020 Dec 10; 11(12):1045. PubMed ID: 33303756
    [Abstract] [Full Text] [Related]

  • 3. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR, Geerts D, Mooney M, El-Khawaja R, Koster J, Bachmann AS.
    Biochem J; 2018 Jan 31; 475(2):531-545. PubMed ID: 29295892
    [Abstract] [Full Text] [Related]

  • 4. Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma.
    Park BS, Jeon H, Kim Y, Kwon H, Choi GE, Chi SG, Park HM, Lee H, Kim T.
    Mol Cancer; 2024 Jul 04; 23(1):136. PubMed ID: 38965534
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer.
    Kim HI, Schultz CR, Chandramouli GVR, Geerts D, Risinger JI, Bachmann AS.
    J Drug Target; 2022 Jul 04; 30(6):623-633. PubMed ID: 35100927
    [Abstract] [Full Text] [Related]

  • 6. Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae.
    Halwas K, Döring LM, Oehlert FV, Dohmen RJ.
    Int J Mol Sci; 2022 Oct 26; 23(21):. PubMed ID: 36361762
    [Abstract] [Full Text] [Related]

  • 7. Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells.
    Ozfiliz P, Kizilboga T, Demir S, Alkurt G, Palavan-Unsal N, Arisan ED, Dinler-Doganay G.
    Cell Biochem Funct; 2015 Jul 26; 33(5):293-307. PubMed ID: 26178413
    [Abstract] [Full Text] [Related]

  • 8. Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
    Nilsson JA, Keller UB, Baudino TA, Yang C, Norton S, Old JA, Nilsson LM, Neale G, Kramer DL, Porter CW, Cleveland JL.
    Cancer Cell; 2005 May 26; 7(5):433-44. PubMed ID: 15894264
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  • 14. Independent roles of eIF5A and polyamines in cell proliferation.
    Nishimura K, Murozumi K, Shirahata A, Park MH, Kashiwagi K, Igarashi K.
    Biochem J; 2005 Feb 01; 385(Pt 3):779-85. PubMed ID: 15377278
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  • 15. Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy.
    Bourourou M, Gouix E, Melis N, Friard J, Heurteaux C, Tauc M, Blondeau N.
    J Cereb Blood Flow Metab; 2021 May 01; 41(5):1080-1090. PubMed ID: 32615885
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  • 16. Anti-IgM-induced growth inhibition and apoptosis are independent of ornithine decarboxylase in Ramos cells.
    Lin CK, Zou HY, Kaptein JS, Yen CF, Kalunta CI, Nguyen TT, Park E, Lad PM.
    Exp Cell Res; 1997 Nov 25; 237(1):231-41. PubMed ID: 9417887
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  • 17. Helicobacter pylori-induced macrophage apoptosis requires activation of ornithine decarboxylase by c-Myc.
    Cheng Y, Chaturvedi R, Asim M, Bussière FI, Scholz A, Xu H, Casero RA, Wilson KT.
    J Biol Chem; 2005 Jun 10; 280(23):22492-6. PubMed ID: 15843384
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  • 18. Critical roles of Myc-ODC axis in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant.
    Funakoshi-Tago M, Sumi K, Kasahara T, Tago K.
    PLoS One; 2013 Jun 10; 8(1):e52844. PubMed ID: 23300995
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  • 20. Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis.
    Packham G, Cleveland JL.
    Mol Cell Biol; 1994 Sep 10; 14(9):5741-7. PubMed ID: 8065308
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