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127 related items for PubMed ID: 3689448

  • 1. Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat. Indications for differential mechanisms of bioactivation.
    Commandeur JN, Oostendorp RA, Schoofs PR, Xu B, Vermeulen NP.
    Biochem Pharmacol; 1987 Dec 15; 36(24):4229-37. PubMed ID: 3689448
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  • 2. Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids.
    Commandeur JN, Stijntjes GJ, Wijngaard J, Vermeulen NP.
    Biochem Pharmacol; 1991 Jun 21; 42(1):31-8. PubMed ID: 2069595
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  • 3. Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms.
    Commandeur JN, Brakenhoff JP, De Kanter FJ, Vermeulen NP.
    Biochem Pharmacol; 1988 Dec 01; 37(23):4495-504. PubMed ID: 3202890
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  • 4. Effect of beta-naphthoflavone and phenobarbital on the nephrotoxicity of chlorotrifluoroethylene and 1,1-dichloro-2,2-difluoroethylene in the rat.
    Morel G, Ban M, Bonnet P, Zissu D, Brondeau MT.
    J Appl Toxicol; 2005 Dec 01; 25(2):153-65. PubMed ID: 15744758
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  • 5. Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney. Uptake of the conjugates and activation to toxic metabolites.
    Boogaard PJ, Commandeur JN, Mulder GJ, Vermeulen NP, Nagelkerke JF.
    Biochem Pharmacol; 1989 Nov 01; 38(21):3731-41. PubMed ID: 2597169
    [Abstract] [Full Text] [Related]

  • 6. Bioactivation of S-(2,2-dihalo-1,1-difluoroethyl)-L-cysteines and S-(trihalovinyl)-L-cysteines by cysteine S-conjugate beta-lyase: indications for formation of both thionoacylating species and thiiranes as reactive intermediates.
    Commandeur JN, King LJ, Koymans L, Vermeulen NP.
    Chem Res Toxicol; 1996 Nov 01; 9(7):1092-102. PubMed ID: 8902263
    [Abstract] [Full Text] [Related]

  • 7. Metabolic activation of the nephrotoxic haloalkene 1,1,2-trichloro-3,3,3-trifluoro-1-propene by glutathione conjugation.
    Vamvakas S, Kremling E, Dekant W.
    Biochem Pharmacol; 1989 Jul 15; 38(14):2297-304. PubMed ID: 2751695
    [Abstract] [Full Text] [Related]

  • 8. The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat.
    Lock EA, Ishmael J.
    Arch Toxicol; 1998 May 15; 72(6):347-54. PubMed ID: 9657282
    [Abstract] [Full Text] [Related]

  • 9. Primary culture of proximal tubular cells from normal rat kidney as an in vitro model to study mechanisms of nephrotoxicity. Toxicity of nephrotoxicants at low concentrations during prolonged exposure.
    Boogaard PJ, Zoeteweij JP, van Berkel TJ, van't Noordende JM, Mulder GJ, Nagelkerke JF.
    Biochem Pharmacol; 1990 Apr 15; 39(8):1335-45. PubMed ID: 2322315
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  • 15. Biochemical toxicology of unsaturated halogenated monomers.
    Jaeger RJ, Conolly RB, Reynolds ES, Murphy SD.
    Environ Health Perspect; 1975 Jun 15; 11():121-8. PubMed ID: 1175549
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  • 16. L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?
    Cooper AJ, Krasnikov BF, Okuno E, Jeitner TM.
    Biochem J; 2003 Nov 15; 376(Pt 1):169-78. PubMed ID: 12859250
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  • 18. Nephrotoxicity of the glutathione and cysteine S-conjugates of the sevoflurane degradation product 2-(fluoromethoxy)-1,1,3,3, 3-pentafluoro-1-propene (Compound A) in male Fischer 344 rats.
    Iyer RA, Baggs RB, Anders MW.
    J Pharmacol Exp Ther; 1997 Dec 15; 283(3):1544-51. PubMed ID: 9400032
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  • 19. Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase.
    Dekant W, Vamvakas S, Anders MW.
    Drug Metab Rev; 1989 Dec 15; 20(1):43-83. PubMed ID: 2653763
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  • 20. Sex differences in hexachlorobutadiene biotransformation and nephrotoxicity.
    Birner G, Werner M, Ott MM, Dekant W.
    Toxicol Appl Pharmacol; 1995 Jun 15; 132(2):203-12. PubMed ID: 7785049
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