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PUBMED FOR HANDHELDS

Journal Abstract Search


295 related items for PubMed ID: 36903470

  • 1. Supersaturation and Precipitation Applicated in Drug Delivery Systems: Development Strategies and Evaluation Approaches.
    Gan Y, Baak JPA, Chen T, Ye H, Liao W, Lv H, Wen C, Zheng S.
    Molecules; 2023 Feb 27; 28(5):. PubMed ID: 36903470
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of gastrointestinal drug supersaturation and precipitation: strategies and issues.
    Bevernage J, Brouwers J, Brewster ME, Augustijns P.
    Int J Pharm; 2013 Aug 30; 453(1):25-35. PubMed ID: 23194883
    [Abstract] [Full Text] [Related]

  • 3. Biorelevant dissolution testing and physiologically based absorption modeling to predict in vivo performance of supersaturating drug delivery systems.
    Thakore SD, Sirvi A, Joshi VC, Panigrahi SS, Manna A, Singh R, Sangamwar AT, Bansal AK.
    Int J Pharm; 2021 Sep 25; 607():120958. PubMed ID: 34332060
    [Abstract] [Full Text] [Related]

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  • 5. In vitro-in vivo correlation of the effect of supersaturation on the intestinal absorption of BCS Class 2 drugs.
    Higashino H, Hasegawa T, Yamamoto M, Matsui R, Masaoka Y, Kataoka M, Sakuma S, Yamashita S.
    Mol Pharm; 2014 Mar 03; 11(3):746-54. PubMed ID: 24460473
    [Abstract] [Full Text] [Related]

  • 6. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS).
    Tsume Y, Matsui K, Searls AL, Takeuchi S, Amidon GE, Sun D, Amidon GL.
    Eur J Pharm Sci; 2017 May 01; 102():126-139. PubMed ID: 28263914
    [Abstract] [Full Text] [Related]

  • 7. In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole.
    Hens B, Pathak SM, Mitra A, Patel N, Liu B, Patel S, Jamei M, Brouwers J, Augustijns P, Turner DB.
    Mol Pharm; 2017 Dec 04; 14(12):4321-4333. PubMed ID: 28817288
    [Abstract] [Full Text] [Related]

  • 8. Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors.
    Madsen CM, Boyd B, Rades T, Müllertz A.
    Eur J Pharm Sci; 2016 Aug 25; 91():31-9. PubMed ID: 27260089
    [Abstract] [Full Text] [Related]

  • 9. Improved Prediction of in Vivo Supersaturation and Precipitation of Poorly Soluble Weakly Basic Drugs Using a Biorelevant Bicarbonate Buffer in a Gastrointestinal Transfer Model.
    Jede C, Wagner C, Kubas H, Weigandt M, Weber C, Lecomte M, Badolo L, Koziolek M, Weitschies W.
    Mol Pharm; 2019 Sep 03; 16(9):3938-3947. PubMed ID: 31335153
    [Abstract] [Full Text] [Related]

  • 10. Microarray Plate Method for Estimation of Precipitation Kinetics of Celecoxib under Biorelevant Conditions and Precipitate Characterization.
    Sodhi I, Sangamwar AT.
    Mol Pharm; 2018 Jun 04; 15(6):2423-2436. PubMed ID: 29746138
    [Abstract] [Full Text] [Related]

  • 11. In Vitro, in Silico, and in Vivo Assessments of Intestinal Precipitation and Its Impact on Bioavailability of a BCS Class 2 Basic Compound.
    Kou D, Zhang C, Yiu H, Ng T, Lubach JW, Janson M, Mao C, Durk M, Chinn L, Winter H, Wigman L, Yehl P.
    Mol Pharm; 2018 Apr 02; 15(4):1607-1617. PubMed ID: 29522347
    [Abstract] [Full Text] [Related]

  • 12. In vivo evaluation of supersaturation/precipitation/re-dissolution behavior of cinnarizine, a lipophilic weak base, in the gastrointestinal tract: the key process of oral absorption.
    Tanaka Y, Kawakami A, Nanimatsu A, Horio M, Matsuoka J, Wada T, Kasaoka S, Yoshikawa H.
    Eur J Pharm Sci; 2017 Jan 01; 96():464-471. PubMed ID: 27773836
    [Abstract] [Full Text] [Related]

  • 13. Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach.
    Hens B, Bermejo M, Tsume Y, Gonzalez-Alvarez I, Ruan H, Matsui K, Amidon GE, Cavanagh KL, Kuminek G, Benninghoff G, Fan J, Rodríguez-Hornedo N, Amidon GL.
    Eur J Pharm Sci; 2018 Mar 30; 115():258-269. PubMed ID: 29378253
    [Abstract] [Full Text] [Related]

  • 14. The effects of degree and duration of supersaturation on in vivo absorption profiles for highly permeable drugs, dipyridamole and ketoconazole.
    Higashino H, Minami K, Takagi T, Kataoka M, Yamashita S.
    Eur J Pharm Biopharm; 2023 Aug 30; 189():48-55. PubMed ID: 37301301
    [Abstract] [Full Text] [Related]

  • 15. A Stratified Analysis of Supersaturation and Precipitation Effects Based on the Refined Developability Classification System (rDCS).
    Beran K, Hermans E, Holm R, Sepassi K, Dressman J.
    J Pharm Sci; 2024 Sep 30; 113(9):2940-2946. PubMed ID: 38908795
    [Abstract] [Full Text] [Related]

  • 16. Bioavailability Improvement Strategies for Poorly Water-Soluble Drugs Based on the Supersaturation Mechanism: An Update.
    Yang M, Gong W, Wang Y, Shan L, Li Y, Gao C.
    J Pharm Pharm Sci; 2016 Sep 30; 19(2):208-25. PubMed ID: 27518171
    [Abstract] [Full Text] [Related]

  • 17. Mathematical Models to Explore Potential Effects of Supersaturation and Precipitation on Oral Bioavailability of Poorly Soluble Drugs.
    Kleppe MS, Forney-Stevens KM, Haskell RJ, Bogner RH.
    AAPS J; 2015 Jul 30; 17(4):902-17. PubMed ID: 25851513
    [Abstract] [Full Text] [Related]

  • 18. Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs.
    Suys EJA, Brundel DHS, Chalmers DK, Pouton CW, Porter CJH.
    J Control Release; 2021 Mar 10; 331():45-61. PubMed ID: 33450318
    [Abstract] [Full Text] [Related]

  • 19. Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation.
    Suys EJA, Chalmers DK, Pouton CW, Porter CJH.
    Mol Pharm; 2018 Jun 04; 15(6):2355-2371. PubMed ID: 29659287
    [Abstract] [Full Text] [Related]

  • 20. Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor.
    Strindberg S, Plum J, Stie MB, Christiansen ML, Hagner Nielsen L, Rades T, Müllertz A.
    Eur J Pharm Biopharm; 2020 Jun 04; 151():108-115. PubMed ID: 32298758
    [Abstract] [Full Text] [Related]


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