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152 related items for PubMed ID: 3698174

  • 1. Altered pharmacokinetics in the mechanism of chemosensitization: effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards.
    Lee FY, Workman P.
    Cancer Chemother Pharmacol; 1986; 17(1):30-7. PubMed ID: 3698174
    [Abstract] [Full Text] [Related]

  • 2. Pharmacokinetic basis for the comparative antitumour activity and toxicity of chlorambucil, phenylacetic acid mustard and beta, beta-difluorochlorambucil (CB 7103) in mice.
    Lee FY, Coe P, Workman P.
    Cancer Chemother Pharmacol; 1986; 17(1):21-9. PubMed ID: 3698173
    [Abstract] [Full Text] [Related]

  • 3. Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU.
    Workman P, Twentyman PR.
    Br J Cancer; 1982 Aug; 46(2):249-59. PubMed ID: 7150475
    [Abstract] [Full Text] [Related]

  • 4. Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice.
    Lee FY, Workman P.
    Br J Cancer; 1983 May; 47(5):659-69. PubMed ID: 6849803
    [Abstract] [Full Text] [Related]

  • 5. Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU.
    Twentyman P, Workman P.
    Br J Cancer; 1982 Mar; 45(3):447-55. PubMed ID: 7073938
    [Abstract] [Full Text] [Related]

  • 6. Chemosensitization by lipophilic nitroimidazoles.
    Twentyman PR, Workman P.
    Br J Cancer; 1983 Jul; 48(1):17-26. PubMed ID: 6871076
    [Abstract] [Full Text] [Related]

  • 7. An investigation of the possibility of chemosensitization by clinically achievable concentrations of misonidazole.
    Twentyman PR, Workman P.
    Br J Cancer; 1983 Feb; 47(2):187-94. PubMed ID: 6824566
    [Abstract] [Full Text] [Related]

  • 8. Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships.
    Workman P, Twentyman PR.
    Int J Radiat Oncol Biol Phys; 1982 Feb; 8(3-4):623-6. PubMed ID: 7107385
    [Abstract] [Full Text] [Related]

  • 9. Misonidazole and CCNU: further evidence for a pharmacokinetic mechanism of chemosensitization and therapeutic gain.
    Lee FY, Workman P.
    Br J Cancer; 1984 May; 49(5):579-85. PubMed ID: 6722006
    [Abstract] [Full Text] [Related]

  • 10. Enhancement of the DNA cross-linking activity of melphalan by misonidazole in vivo.
    Murray D, Meyn RE.
    Br J Cancer; 1983 Feb; 47(2):195-203. PubMed ID: 6824567
    [Abstract] [Full Text] [Related]

  • 11. Misonidazole and benznidazole inhibit hydroxylation of CCNU by mouse liver microsomal cytochrome P-450 in vitro.
    Lee FY, Workman P, Cheeseman KH.
    Biochem Pharmacol; 1987 Apr 15; 36(8):1349-55. PubMed ID: 3593422
    [Abstract] [Full Text] [Related]

  • 12. Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers.
    Siemann DW.
    Br J Cancer; 1982 Feb 15; 45(2):272-81. PubMed ID: 6460517
    [Abstract] [Full Text] [Related]

  • 13. In vivo chemosensitization by misonidazole in sensitive and resistant tumor lines.
    Mulcahy RT, Siemann DW.
    Cancer Res; 1983 Oct 15; 43(10):4709-13. PubMed ID: 6883329
    [Abstract] [Full Text] [Related]

  • 14. Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
    Lee FY, Workman P.
    Int J Radiat Oncol Biol Phys; 1984 Sep 15; 10(9):1627-30. PubMed ID: 6237080
    [Abstract] [Full Text] [Related]

  • 15. The effect of radiosensitizers on the pharmacokinetics of melphalan and cyclophosphamide in the mouse.
    Hinchliffe M, McNally NJ, Stratford MR.
    Br J Cancer; 1983 Sep 15; 48(3):375-83. PubMed ID: 6615699
    [Abstract] [Full Text] [Related]

  • 16. Comparative study of thermoradiosensitization by misonidazole and metronidazole in vivo: antitumour effect and pharmacokinetics.
    Wong KH, Maezawa H, Urano M.
    Int J Hyperthermia; 1992 Sep 15; 8(5):645-58. PubMed ID: 1402141
    [Abstract] [Full Text] [Related]

  • 17. Misonidazole protects mouse tumour and normal tissues from the toxicity of oral CCNU.
    Lee FY, Workman P.
    Br J Cancer; 1985 Jan 15; 51(1):85-91. PubMed ID: 3966974
    [Abstract] [Full Text] [Related]

  • 18. The effect of radiosensitizer pretreatment on the response of the RIF-1 mouse sarcoma to cytotoxic drugs.
    Twentyman PR, Workman P.
    Int J Radiat Oncol Biol Phys; 1982 Jan 15; 8(3-4):611-3. PubMed ID: 7107382
    [Abstract] [Full Text] [Related]

  • 19. Modification of tumour and host response to cyclophosphamide by misonidazole and by WR 2721.
    Twentyman PR.
    Br J Cancer; 1981 Jun 15; 43(6):745-55. PubMed ID: 6264941
    [Abstract] [Full Text] [Related]

  • 20. Potentiation of melphalan activity in the KHT sarcoma by the radiosensitizer RSU 1069.
    Siemann DW, Maddison K, Wolf K.
    Int J Radiat Oncol Biol Phys; 1984 Sep 15; 10(9):1657-60. PubMed ID: 6548212
    [Abstract] [Full Text] [Related]

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