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157 related items for PubMed ID: 37048086

  • 1. Ethanol Exposure to Ethanol-Oxidizing HEPG2 Cells Induces Intracellular Protein Aggregation.
    Thomes PG, Rensch G, Casey CA, Donohue TM.
    Cells; 2023 Mar 26; 12(7):. PubMed ID: 37048086
    [Abstract] [Full Text] [Related]

  • 2. Recombinant Hep G2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity.
    Donohue TM, Osna NA, Clemens DL.
    Int J Biochem Cell Biol; 2006 Jan 26; 38(1):92-101. PubMed ID: 16181800
    [Abstract] [Full Text] [Related]

  • 3. Interferon gamma enhances proteasome activity in recombinant Hep G2 cells that express cytochrome P4502E1: modulation by ethanol.
    Osna NA, Clemens DL, Donohue TM.
    Biochem Pharmacol; 2003 Sep 01; 66(5):697-710. PubMed ID: 12948850
    [Abstract] [Full Text] [Related]

  • 4. Elevated glutathione level does not protect against chronic alcohol mediated apoptosis in recombinant human hepatoma cell line VL-17A over-expressing alcohol metabolizing enzymes--alcohol dehydrogenase and Cytochrome P450 2E1.
    Chandrasekaran K, Swaminathan K, Kumar SM, Chatterjee S, Clemens DL, Dey A.
    Toxicol In Vitro; 2011 Jun 01; 25(4):969-78. PubMed ID: 21414402
    [Abstract] [Full Text] [Related]

  • 5. Cellular steatosis in ethanol oxidizing-HepG2 cells is partially controlled by the transcription factor, early growth response-1.
    Thomes PG, Osna NA, Davis JS, Donohue TM.
    Int J Biochem Cell Biol; 2013 Feb 01; 45(2):454-63. PubMed ID: 23103837
    [Abstract] [Full Text] [Related]

  • 6. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation.
    Bardag-Gorce F, French BA, Nan L, Song H, Nguyen SK, Yong H, Dede J, French SW.
    Exp Mol Pathol; 2006 Dec 01; 81(3):191-201. PubMed ID: 17034788
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure.
    Swaminathan K, Clemens DL, Dey A.
    Life Sci; 2013 Mar 14; 92(6-7):325-36. PubMed ID: 23352969
    [Abstract] [Full Text] [Related]

  • 8. Ethanol metabolism by alcohol dehydrogenase or cytochrome P450 2E1 differentially impairs hepatic protein trafficking and growth hormone signaling.
    Doody EE, Groebner JL, Walker JR, Frizol BM, Tuma DJ, Fernandez DJ, Tuma PL.
    Am J Physiol Gastrointest Liver Physiol; 2017 Dec 01; 313(6):G558-G569. PubMed ID: 28864499
    [Abstract] [Full Text] [Related]

  • 9. Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells.
    Thomes PG, Ehlers RA, Trambly CS, Clemens DL, Fox HS, Tuma DJ, Donohue TM.
    Autophagy; 2013 Jan 01; 9(1):63-73. PubMed ID: 23090141
    [Abstract] [Full Text] [Related]

  • 10. In vitro evidence for chronic alcohol and high glucose mediated increased oxidative stress and hepatotoxicity.
    Chandrasekaran K, Swaminathan K, Mathan Kumar S, Clemens DL, Dey A.
    Alcohol Clin Exp Res; 2012 Jun 01; 36(6):1004-12. PubMed ID: 22309822
    [Abstract] [Full Text] [Related]

  • 11. Alcohol dehydrogenase and cytochrome P450 2E1 can be induced by long-term exposure to ethanol in cultured liver HEP-G2 cells.
    Balusikova K, Kovar J.
    In Vitro Cell Dev Biol Anim; 2013 Sep 01; 49(8):619-25. PubMed ID: 23824954
    [Abstract] [Full Text] [Related]

  • 12. Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: role of nonoxidative metabolism.
    Wu H, Cai P, Clemens DL, Jerrells TR, Ansari GA, Kaphalia BS.
    Toxicol Appl Pharmacol; 2006 Oct 15; 216(2):238-47. PubMed ID: 16806343
    [Abstract] [Full Text] [Related]

  • 13. Proteasome activation by hepatitis C core protein is reversed by ethanol-induced oxidative stress.
    Osna NA, White RL, Krutik VM, Wang T, Weinman SA, Donohue TM.
    Gastroenterology; 2008 Jun 15; 134(7):2144-52. PubMed ID: 18549882
    [Abstract] [Full Text] [Related]

  • 14. Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells.
    Osna NA, Clemens DL, Donohue TM.
    Hepatology; 2005 Nov 15; 42(5):1109-17. PubMed ID: 16250053
    [Abstract] [Full Text] [Related]

  • 15. Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells.
    Osna NA, White RL, Todero S, McVicker BL, Thiele GM, Clemens DL, Tuma DJ, Donohue TM.
    Hepatology; 2007 Jan 15; 45(1):53-61. PubMed ID: 17187415
    [Abstract] [Full Text] [Related]

  • 16. N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression.
    Matsumoto G, Inobe T, Amano T, Murai K, Nukina N, Mori N.
    Sci Rep; 2018 Jun 25; 8(1):9585. PubMed ID: 29941919
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells.
    Swaminathan K, Kumar SM, Clemens DL, Dey A.
    Biochim Biophys Acta; 2013 Oct 25; 1830(10):4407-16. PubMed ID: 23707663
    [Abstract] [Full Text] [Related]

  • 18. Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles.
    Verma VK, Li H, Wang R, Hirsova P, Mushref M, Liu Y, Cao S, Contreras PC, Malhi H, Kamath PS, Gores GJ, Shah VH.
    J Hepatol; 2016 Mar 25; 64(3):651-60. PubMed ID: 26632633
    [Abstract] [Full Text] [Related]

  • 19. The effect of alcohol on Sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC).
    Thompson KJ, Humphries JR, Niemeyer DJ, Sindram D, McKillop IH.
    Adv Exp Med Biol; 2015 Mar 25; 815():361-73. PubMed ID: 25427918
    [Abstract] [Full Text] [Related]

  • 20. Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1.
    Zaarur N, Meriin AB, Gabai VL, Sherman MY.
    J Biol Chem; 2008 Oct 10; 283(41):27575-27584. PubMed ID: 18635553
    [Abstract] [Full Text] [Related]

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