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Journal Abstract Search

160 related items for PubMed ID: 37277066

  • 1. Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its' potential against glioblastoma in cellular models.
    Mathomes RT, Koulas SM, Tsialtas I, Stravodimos G, Welsby PJ, Psarra AG, Stasik I, Leonidas DD, Hayes JM.
    Chem Biol Interact; 2023 Sep 01; 382():110568. PubMed ID: 37277066
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  • 2. Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors.
    Chetter BA, Kyriakis E, Barr D, Karra AG, Katsidou E, Koulas SM, Skamnaki VT, Snape TJ, Psarra AG, Leonidas DD, Hayes JM.
    Bioorg Chem; 2020 Sep 01; 102():104003. PubMed ID: 32771768
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  • 3. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE.
    Food Chem Toxicol; 2013 Nov 01; 61():14-27. PubMed ID: 23279842
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  • 4. Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies.
    Barr D, Szennyes E, Bokor É, Al-Oanzi ZH, Moffatt C, Kun S, Docsa T, Sipos Á, Davies MP, Mathomes RT, Snape TJ, Agius L, Somsák L, Hayes JM.
    ACS Chem Biol; 2019 Jul 19; 14(7):1460-1470. PubMed ID: 31243960
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  • 5. A multidisciplinary study of 3-(β-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors.
    Kun S, Begum J, Kyriakis E, Stamati ECV, Barkas TA, Szennyes E, Bokor É, Szabó KE, Stravodimos GA, Sipos Á, Docsa T, Gergely P, Moffatt C, Patraskaki MS, Kokolaki MC, Gkerdi A, Skamnaki VT, Leonidas DD, Somsák L, Hayes JM.
    Eur J Med Chem; 2018 Mar 10; 147():266-278. PubMed ID: 29453094
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  • 6. Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.
    Németi B, Gregus Z.
    Toxicol Sci; 2007 Nov 10; 100(1):36-43. PubMed ID: 17693425
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  • 8. Discovery and evaluation of novel benzazepinone derivatives as glycogen phosphorylase inhibitors with potent activity.
    Wang Y, Yan Z, Guo Y, Zhang L.
    Future Med Chem; 2021 May 10; 13(10):897-909. PubMed ID: 33906369
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  • 14. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
    Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L.
    J Med Chem; 2006 Sep 21; 49(19):5687-701. PubMed ID: 16970395
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  • 16. A new allosteric site in glycogen phosphorylase b as a target for drug interactions.
    Oikonomakos NG, Skamnaki VT, Tsitsanou KE, Gavalas NG, Johnson LN.
    Structure; 2000 Jun 15; 8(6):575-84. PubMed ID: 10873856
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  • 18. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM, Hayes JM, Tiraidis C, Zographos SE, Leonidas DD, Chrysina ED, Archontis G, Oikonomakos NG, Paul JV, Varghese B, Loganathan D.
    Proteins; 2008 May 15; 71(3):1307-23. PubMed ID: 18041758
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  • 20. Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors.
    Gregus Z, Németi B.
    Toxicol Sci; 2007 Nov 15; 100(1):44-53. PubMed ID: 17693424
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