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Journal Abstract Search

145 related items for PubMed ID: 37298123

  • 1. Genetic Ablation of LAT1 Inhibits Growth of Liver Cancer Cells and Downregulates mTORC1 Signaling.
    Kim SY, Ong Q, Liao Y, Ding Z, Tan AQL, Lim LTR, Tan HM, Lim SL, Lee QY, Han W.
    Int J Mol Sci; 2023 May 24; 24(11):. PubMed ID: 37298123
    [Abstract] [Full Text] [Related]

  • 2. Targeted Suppression and Knockout of ASCT2 or LAT1 in Epithelial and Mesenchymal Human Liver Cancer Cells Fail to Inhibit Growth.
    Bothwell PJ, Kron CD, Wittke EF, Czerniak BN, Bode BP.
    Int J Mol Sci; 2018 Jul 19; 19(7):. PubMed ID: 30029480
    [Abstract] [Full Text] [Related]

  • 3. The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5).
    Cormerais Y, Massard PA, Vucetic M, Giuliano S, Tambutté E, Durivault J, Vial V, Endou H, Wempe MF, Parks SK, Pouyssegur J.
    J Biol Chem; 2018 Feb 23; 293(8):2877-2887. PubMed ID: 29326164
    [Abstract] [Full Text] [Related]

  • 4. Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth.
    Cormerais Y, Giuliano S, LeFloch R, Front B, Durivault J, Tambutté E, Massard PA, de la Ballina LR, Endou H, Wempe MF, Palacin M, Parks SK, Pouyssegur J.
    Cancer Res; 2016 Aug 01; 76(15):4481-92. PubMed ID: 27302165
    [Abstract] [Full Text] [Related]

  • 5. Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
    Quan L, Ohgaki R, Hara S, Okuda S, Wei L, Okanishi H, Nagamori S, Endou H, Kanai Y.
    J Exp Clin Cancer Res; 2020 Nov 30; 39(1):266. PubMed ID: 33256804
    [Abstract] [Full Text] [Related]

  • 6. The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.
    Ozaki K, Yamada T, Horie T, Ishizaki A, Hiraiwa M, Iezaki T, Park G, Fukasawa K, Kamada H, Tokumura K, Motono M, Kaneda K, Ogawa K, Ochi H, Sato S, Kobayashi Y, Shi YB, Taylor PM, Hinoi E.
    Sci Signal; 2019 Jul 09; 12(589):. PubMed ID: 31289211
    [Abstract] [Full Text] [Related]

  • 7. Persistent mTORC1 activation via Depdc5 deletion results in spontaneous hepatocellular carcinoma but does not exacerbate carcinogen- and high-fat diet-induced hepatic carcinogenesis in mice.
    Xu L, Yang C, Wang J, Li Z, Huang R, Ma H, Ma J, Wang Q, Xiong X.
    Biochem Biophys Res Commun; 2021 Nov 12; 578():142-149. PubMed ID: 34562654
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  • 9. Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
    Nishikubo K, Ohgaki R, Okanishi H, Okuda S, Xu M, Endou H, Kanai Y.
    J Cell Mol Med; 2022 Oct 12; 26(20):5246-5256. PubMed ID: 36071551
    [Abstract] [Full Text] [Related]

  • 10. Methionine Induces LAT1 Expression in Dairy Cow Mammary Gland by Activating the mTORC1 Signaling Pathway.
    Duan X, Lin Y, Lv H, Yang Y, Jiao H, Hou X.
    DNA Cell Biol; 2017 Dec 12; 36(12):1126-1133. PubMed ID: 29040000
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  • 13. BUB1B promotes hepatocellular carcinoma progression via activation of the mTORC1 signaling pathway.
    Qiu J, Zhang S, Wang P, Wang H, Sha B, Peng H, Ju Z, Rao J, Lu L.
    Cancer Med; 2020 Nov 12; 9(21):8159-8172. PubMed ID: 32977361
    [Abstract] [Full Text] [Related]

  • 14. Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma.
    Dong P, Wang X, Liu L, Tang W, Ma L, Zeng W, Sun S, Zhang L, Zhang N, Shen X, Janssen HLA, Dong L, Zhang S, Chen S.
    J Hepatol; 2020 Dec 12; 73(6):1446-1459. PubMed ID: 32610114
    [Abstract] [Full Text] [Related]

  • 15. LncRNA LINC00958 Activates mTORC1/P70S6K Signalling Pathway to Promote Epithelial-Mesenchymal Transition Process in the Hepatocellular Carcinoma.
    Lan C, Wang Y, Su X, Lu J, Ma S.
    Cancer Invest; 2021 Dec 12; 39(6-7):539-549. PubMed ID: 33979257
    [Abstract] [Full Text] [Related]

  • 16. Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma.
    Ohshima Y, Kaira K, Yamaguchi A, Oriuchi N, Tominaga H, Nagamori S, Kanai Y, Yokobori T, Miyazaki T, Asao T, Tsushima Y, Kuwano H, Ishioka NS.
    Cancer Sci; 2016 Oct 12; 107(10):1499-1505. PubMed ID: 27465934
    [Abstract] [Full Text] [Related]

  • 17. Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma.
    Park YY, Sohn BH, Johnson RL, Kang MH, Kim SB, Shim JJ, Mangala LS, Kim JH, Yoo JE, Rodriguez-Aguayo C, Pradeep S, Hwang JE, Jang HJ, Lee HS, Rupaimoole R, Lopez-Berestein G, Jeong W, Park IS, Park YN, Sood AK, Mills GB, Lee JS.
    Hepatology; 2016 Jan 12; 63(1):159-72. PubMed ID: 26389641
    [Abstract] [Full Text] [Related]

  • 18. CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway.
    Zhang S, Zhang F, Chen Q, Wan C, Xiong J, Xu J.
    J Exp Clin Cancer Res; 2019 Nov 14; 38(1):467. PubMed ID: 31727171
    [Abstract] [Full Text] [Related]

  • 19. Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics.
    Kanai Y.
    Pharmacol Ther; 2022 Feb 14; 230():107964. PubMed ID: 34390745
    [Abstract] [Full Text] [Related]

  • 20. Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis.
    Jia J, Che L, Cigliano A, Wang X, Peitta G, Tao J, Zhong S, Ribback S, Evert M, Chen X, Calvisi DF.
    Int J Mol Sci; 2020 Nov 11; 21(22):. PubMed ID: 33187130
    [Abstract] [Full Text] [Related]

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