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476 related items for PubMed ID: 37337279

  • 1. Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.
    Williams T, Bathe T, Vo Q, Sacilotto P, McFarland K, Ruiz AJ, Hery GP, Sullivan P, Borchelt DR, Prokop S, Chakrabarty P.
    Acta Neuropathol Commun; 2023 Jun 19; 11(1):99. PubMed ID: 37337279
    [Abstract] [Full Text] [Related]

  • 2. Impact of APOE genotype on prion-type propagation of tauopathy.
    Williams T, Ruiz AJ, Ruiz AM, Vo Q, Tsering W, Xu G, McFarland K, Giasson BI, Sullivan P, Borchelt DR, Chakrabarty P.
    Acta Neuropathol Commun; 2022 Apr 19; 10(1):57. PubMed ID: 35440098
    [Abstract] [Full Text] [Related]

  • 3. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
    Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C, Alzheimer’s Disease Neuroimaging Initiative, Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM.
    Nature; 2017 Sep 28; 549(7673):523-527. PubMed ID: 28959956
    [Abstract] [Full Text] [Related]

  • 4. Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer's Disease.
    Nakamura T, Kawarabayashi T, Ueda T, Shimomura S, Hoshino M, Itoh K, Ihara K, Nakaji S, Takatama M, Ikeda Y, Shoji M.
    J Alzheimers Dis; 2023 Sep 28; 93(1):333-348. PubMed ID: 36970894
    [Abstract] [Full Text] [Related]

  • 5. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
    Huang YA, Zhou B, Nabet AM, Wernig M, Südhof TC.
    J Neurosci; 2019 Sep 11; 39(37):7408-7427. PubMed ID: 31331998
    [Abstract] [Full Text] [Related]

  • 6. Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
    Litvinchuk A, Suh JH, Guo JL, Lin K, Davis SS, Bien-Ly N, Tycksen E, Tabor GT, Remolina Serrano J, Manis M, Bao X, Lee C, Bosch M, Perez EJ, Yuede CM, Cashikar AG, Ulrich JD, Di Paolo G, Holtzman DM.
    Neuron; 2024 Feb 07; 112(3):384-403.e8. PubMed ID: 37995685
    [Abstract] [Full Text] [Related]

  • 7. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
    Aleshkov S, Abraham CR, Zannis VI.
    Biochemistry; 1997 Aug 26; 36(34):10571-80. PubMed ID: 9265639
    [Abstract] [Full Text] [Related]

  • 8. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
    Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y.
    J Neurosci; 2004 Mar 10; 24(10):2527-34. PubMed ID: 15014128
    [Abstract] [Full Text] [Related]

  • 9. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
    Hu J, Liu CC, Chen XF, Zhang YW, Xu H, Bu G.
    Mol Neurodegener; 2015 Mar 05; 10():6. PubMed ID: 25871773
    [Abstract] [Full Text] [Related]

  • 10. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
    Honda K, Saito Y, Saito H, Toyoda M, Abe R, Saito T, Saido TC, Michikawa M, Taru H, Sobu Y, Hata S, Nakaya T, Suzuki T.
    Neurobiol Aging; 2023 Mar 05; 123():63-74. PubMed ID: 36638682
    [Abstract] [Full Text] [Related]

  • 11. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Butterfield DA, Mattson MP.
    Neurobiol Dis; 2020 May 05; 138():104795. PubMed ID: 32036033
    [Abstract] [Full Text] [Related]

  • 12. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
    Kunzler J, Youmans KL, Yu C, Ladu MJ, Tai LM.
    Neurosci Lett; 2014 Feb 07; 560():131-6. PubMed ID: 24368217
    [Abstract] [Full Text] [Related]

  • 13. Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging.
    Peng KY, Liemisa B, Pasato J, D'Acunzo P, Pawlik M, Heguy A, Penikalapati SC, Labuza A, Pidikiti H, Alldred MJ, Ginsberg SD, Levy E, Mathews PM.
    Traffic; 2024 May 07; 25(5):e12937. PubMed ID: 38777335
    [Abstract] [Full Text] [Related]

  • 14. Human Apolipoprotein E Genotype Differentially Affects Olfactory Behavior and Sensory Physiology in Mice.
    East BS, Fleming G, Peng K, Olofsson JK, Levy E, Mathews PM, Wilson DA.
    Neuroscience; 2018 Jun 01; 380():103-110. PubMed ID: 29678753
    [Abstract] [Full Text] [Related]

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  • 16. A multi-hit hypothesis for an APOE4-dependent pathophysiological state.
    Steele OG, Stuart AC, Minkley L, Shaw K, Bonnar O, Anderle S, Penn AC, Rusted J, Serpell L, Hall C, King S.
    Eur J Neurosci; 2022 Nov 01; 56(9):5476-5515. PubMed ID: 35510513
    [Abstract] [Full Text] [Related]

  • 17. Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
    Koller EJ, Gonzalez De La Cruz E, Weinrich M, Williams T, Cruz PE, Ryu D, Golde TE, Sullivan PM, Lewis J, Borchelt DR, Chakrabarty P.
    Mol Neurobiol; 2020 Apr 01; 57(4):1986-2001. PubMed ID: 31903524
    [Abstract] [Full Text] [Related]

  • 18. Effect of Chronic Cadmium Exposure on Brain and Liver Transporters and Drug-Metabolizing Enzymes in Male and Female Mice Genetically Predisposed to Alzheimer's Disease.
    Wang H, Zhang L, Xia Z, Cui JY.
    Drug Metab Dispos; 2022 Oct 01; 50(10):1414-1428. PubMed ID: 35878927
    [Abstract] [Full Text] [Related]

  • 19. APOE genotype alters glial activation and loss of synaptic markers in mice.
    Zhu Y, Nwabuisi-Heath E, Dumanis SB, Tai LM, Yu C, Rebeck GW, LaDu MJ.
    Glia; 2012 Apr 01; 60(4):559-69. PubMed ID: 22228589
    [Abstract] [Full Text] [Related]

  • 20. APOE effects on regional tau in preclinical Alzheimer's disease.
    Young CB, Johns E, Kennedy G, Belloy ME, Insel PS, Greicius MD, Sperling RA, Johnson KA, Poston KL, Mormino EC, Alzheimer’s Disease Neuroimaging Initiative, A4 Study Team.
    Mol Neurodegener; 2023 Jan 04; 18(1):1. PubMed ID: 36597122
    [Abstract] [Full Text] [Related]

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