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PUBMED FOR HANDHELDS

Journal Abstract Search


200 related items for PubMed ID: 37375750

  • 1. Design, Synthesis, Biological Evaluation, and Molecular Docking Study of 4,6-Dimethyl-5-aryl/alkyl-2-[2-hydroxy-3-(4-substituted-1-piperazinyl)propyl]pyrrolo[3,4-c]pyrrole-1,3(2H,5H)-diones as Anti-Inflammatory Agents with Dual Inhibition of COX and LOX.
    Redzicka A, Wiatrak B, Jęśkowiak-Kossakowska I, Kochel A, Płaczek R, Czyżnikowska Ż.
    Pharmaceuticals (Basel); 2023 May 29; 16(6):. PubMed ID: 37375750
    [Abstract] [Full Text] [Related]

  • 2. Design and Synthesis of N-Substituted 3,4-Pyrroledicarboximides as Potential Anti-Inflammatory Agents.
    Redzicka A, Czyżnikowska Ż, Wiatrak B, Gębczak K, Kochel A.
    Int J Mol Sci; 2021 Jan 30; 22(3):. PubMed ID: 33573356
    [Abstract] [Full Text] [Related]

  • 3. COX-1/COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
    Redzicka A, Szczukowski Ł, Kochel A, Wiatrak B, Gębczak K, Czyżnikowska Ż.
    Bioorg Med Chem; 2019 Sep 01; 27(17):3918-3928. PubMed ID: 31345747
    [Abstract] [Full Text] [Related]

  • 4. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS, Abdu-Allah HHM, Salem OIA, Kafafy AN, Farghaly HSM.
    Bioorg Chem; 2018 Aug 01; 78():80-93. PubMed ID: 29550533
    [Abstract] [Full Text] [Related]

  • 5. Aryl/heteroaryl Substituted Celecoxib Derivatives as COX-2 Inhibitors: Synthesis, Anti-inflammatory Activity and Molecular Docking Studies.
    Madhava G, Ramana KV, Sudhana SM, Rao DS, Kumar KH, Lokanatha V, Rani AU, Raju CN.
    Med Chem; 2017 Aug 01; 13(5):484-497. PubMed ID: 28228088
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
    Gedawy EM, Kassab AE, El Kerdawy AM.
    Eur J Med Chem; 2020 Mar 01; 189():112066. PubMed ID: 31982653
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
    Omar YM, Abdu-Allah HHM, Abdel-Moty SG.
    Bioorg Chem; 2018 Oct 01; 80():461-471. PubMed ID: 29986191
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones Derivatives.
    Krzyżak E, Szkatuła D, Wiatrak B, Gębarowski T, Marciniak A.
    Molecules; 2020 Jun 25; 25(12):. PubMed ID: 32630594
    [Abstract] [Full Text] [Related]

  • 9. 1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity.
    Naaz F, Preeti Pallavi MC, Shafi S, Mulakayala N, Shahar Yar M, Sampath Kumar HM.
    Bioorg Chem; 2018 Dec 25; 81():1-20. PubMed ID: 30081353
    [Abstract] [Full Text] [Related]

  • 10. Blocking the major inflammatory pathways by newly synthesized thiadiazine derivatives via in-vivo, in-vitro and in-silico mechanism.
    Habib Ullah S, Khan A, Ahsan Halim S, Khan R, Pan XD, Ullah R, Wadood A, Khalid A, Abdalla AN, Khogeer S, Al-Harrasi A.
    Bioorg Chem; 2023 Nov 25; 140():106760. PubMed ID: 37647806
    [Abstract] [Full Text] [Related]

  • 11. One pot domino synthesis of new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thiones (THTTs) as anti-inflammatory and antinociceptive candidates: A proof from in-vivo to in-vitro and in-silico mechanistic studies.
    Raheem S, Khan R, Pan X, Ullah R, Ahsan Halim S, Khan A, Al-Harrasi A.
    Bioorg Chem; 2022 Oct 25; 127():105974. PubMed ID: 35780683
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
    Shaaban MA, Kamal AM, Faggal SI, Farag NA, Aborehab NM, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Nov 25; 353(11):e2000027. PubMed ID: 32696514
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K, Özkanlı F, Jain S, Rao PP, Velázquez-Martínez CA.
    Bioorg Med Chem; 2012 May 01; 20(9):2912-22. PubMed ID: 22475926
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
    Lamie PF, Philoppes JN, Rárová L.
    Arch Pharm (Weinheim); 2018 Apr 01; 351(3-4):e1700311. PubMed ID: 29400411
    [Abstract] [Full Text] [Related]

  • 15. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM.
    Bioorg Chem; 2017 Jun 01; 72():102-115. PubMed ID: 28390993
    [Abstract] [Full Text] [Related]

  • 16. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct 01; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 17. Interactions of N-Mannich Bases of Pyrrolo[3,4-c]pyrrole with Artificial Models of Cell Membranes and Plasma Proteins, Evaluation of Anti-Inflammatory and Antioxidant Activity.
    Szczukowski Ł, Maniewska J, Wiatrak B, Jawień P, Krzyżak E, Kotynia A, Marciniak A, Janeczek M, Redzicka A.
    Membranes (Basel); 2023 Mar 17; 13(3):. PubMed ID: 36984737
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH, Rao PN, Knaus EE.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7898-909. PubMed ID: 16904331
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, Cyclooxygenase-2 Inhibition, Anti-inflammatory Evaluation and Docking Study of Substituted-N-(3,4,5-trimethoxyphenyl)-benzo[d]oxazole Derivatives.
    Kaur A, Wakode S, Pathak DP, Sharma V, Shakya AK.
    Med Chem; 2018 Dec 01; 14(7):660-673. PubMed ID: 29564981
    [Abstract] [Full Text] [Related]

  • 20. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
    Lamie PF, Ali WAM, Bazgier V, Rárová L.
    Eur J Med Chem; 2016 Nov 10; 123():803-813. PubMed ID: 27541263
    [Abstract] [Full Text] [Related]


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