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112 related items for PubMed ID: 37389464

  • 1. The effects of PKI-402 on breast tumor models' radiosensitivity via dual inhibition of PI3K/mTOR.
    Gasimli R, Kayabasi C, Ozmen Yelken B, Asik A, Sogutlu F, Celebi C, Yilmaz Susluer S, Kamer S, Biray Avci C, Haydaroglu A, Gunduz C.
    Int J Radiat Biol; 2023; 99(12):1961-1970. PubMed ID: 37389464
    [Abstract] [Full Text] [Related]

  • 2. Dual PI3K/mTOR inhibitors, GSK2126458 and PKI-587, suppress tumor progression and increase radiosensitivity in nasopharyngeal carcinoma.
    Liu T, Sun Q, Li Q, Yang H, Zhang Y, Wang R, Lin X, Xiao D, Yuan Y, Chen L, Wang W.
    Mol Cancer Ther; 2015 Feb; 14(2):429-39. PubMed ID: 25504751
    [Abstract] [Full Text] [Related]

  • 3. Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor.
    Mallon R, Hollander I, Feldberg L, Lucas J, Soloveva V, Venkatesan A, Dehnhardt C, Delos Santos E, Chen Z, Dos Santos O, Ayral-Kaloustian S, Gibbons J.
    Mol Cancer Ther; 2010 Apr; 9(4):976-84. PubMed ID: 20371716
    [Abstract] [Full Text] [Related]

  • 4. Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma.
    Bamodu OA, Chang HL, Ong JR, Lee WH, Yeh CT, Tsai JT.
    Cells; 2020 Mar 18; 9(3):. PubMed ID: 32197467
    [Abstract] [Full Text] [Related]

  • 5. Antitumor efficacy of PKI-587, a highly potent dual PI3K/mTOR kinase inhibitor.
    Mallon R, Feldberg LR, Lucas J, Chaudhary I, Dehnhardt C, Santos ED, Chen Z, dos Santos O, Ayral-Kaloustian S, Venkatesan A, Hollander I.
    Clin Cancer Res; 2011 May 15; 17(10):3193-203. PubMed ID: 21325073
    [Abstract] [Full Text] [Related]

  • 6. The PI3K/AKT/mTOR signaling pathway inhibitors enhance radiosensitivity in cancer cell lines.
    Mardanshahi A, Gharibkandi NA, Vaseghi S, Abedi SM, Molavipordanjani S.
    Mol Biol Rep; 2021 Aug 15; 48(8):1-14. PubMed ID: 34357550
    [Abstract] [Full Text] [Related]

  • 7. Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy.
    Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, Sun Y, Su J, Sun L.
    Biomed Pharmacother; 2020 Sep 15; 129():110397. PubMed ID: 32585451
    [Abstract] [Full Text] [Related]

  • 8. Sodium alginate encapsulated iron oxide decorated with thymoquinone nanocomposite induces apoptosis in human breast cancer cells via PI3K-Akt-mTOR pathway.
    Alzahrani B, Elderdery AY, Alsrhani A, Alzerwi NAN, Althobiti MM, Elkhalifa AME, Rayzah M, Idrees B, Kumar SS, Mok PL.
    Int J Biol Macromol; 2023 Jul 31; 244():125054. PubMed ID: 37245766
    [Abstract] [Full Text] [Related]

  • 9. Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance.
    Chang L, Graham PH, Hao J, Ni J, Bucci J, Cozzi PJ, Kearsley JH, Li Y.
    Cell Death Dis; 2013 Oct 24; 4(10):e875. PubMed ID: 24157869
    [Abstract] [Full Text] [Related]

  • 10. PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.
    Gedaly R, Angulo P, Hundley J, Daily MF, Chen C, Evers BM.
    J Surg Res; 2012 Aug 24; 176(2):542-8. PubMed ID: 22261591
    [Abstract] [Full Text] [Related]

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  • 12. Inhibitory role of large intergenic noncoding RNA-ROR on tamoxifen resistance in the endocrine therapy of breast cancer by regulating the PI3K/Akt/mTOR signaling pathway.
    Lu PW, Li L, Wang F, Gu YT.
    J Cell Physiol; 2019 Feb 24; 234(2):1904-1912. PubMed ID: 30145819
    [Abstract] [Full Text] [Related]

  • 13. Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer.
    Li P, Zhang Q, Torossian A, Li ZB, Xu WC, Lu B, Fu S.
    Int J Radiat Oncol Biol Phys; 2012 Jul 01; 83(3):e391-7. PubMed ID: 22414288
    [Abstract] [Full Text] [Related]

  • 14. Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling.
    Tohkayomatee R, Reabroi S, Tungmunnithum D, Parichatikanond W, Pinthong D.
    Molecules; 2022 May 31; 27(11):. PubMed ID: 35684480
    [Abstract] [Full Text] [Related]

  • 15. PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer.
    Deng H, Chen Y, Wang L, Zhang Y, Hang Q, Li P, Zhang P, Ji J, Song H, Chen M, Jin Y.
    Cell Death Dis; 2023 Oct 06; 14(10):652. PubMed ID: 37802999
    [Abstract] [Full Text] [Related]

  • 16. PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the PI3K/AKT/mTOR pathways and DNA damage repair.
    Xie Y, Liu C, Zhang Y, Li A, Sun C, Li R, Xing Y, Shi M, Wang Q.
    PLoS One; 2021 Oct 06; 16(10):e0258817. PubMed ID: 34665844
    [Abstract] [Full Text] [Related]

  • 17. Suppression of PI3K/Akt/mTOR/c-Myc/mtp53 Positive Feedback Loop Induces Cell Cycle Arrest by Dual PI3K/mTOR Inhibitor PQR309 in Endometrial Cancer Cell Lines.
    Hsin IL, Shen HP, Chang HY, Ko JL, Wang PH.
    Cells; 2021 Oct 27; 10(11):. PubMed ID: 34831139
    [Abstract] [Full Text] [Related]

  • 18. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.
    Won YS, Seo KI.
    Food Chem Toxicol; 2020 Jan 27; 135():110863. PubMed ID: 31604113
    [Abstract] [Full Text] [Related]

  • 19. Preclinical Evaluation of a Fluorine-18 (18F)-Labeled Phosphatidylinositol 3-Kinase Inhibitor for Breast Cancer Imaging.
    Altine B, Gai Y, Han N, Jiang Y, Ji H, Fang H, Niyonkuru A, Bakari KH, Rajab Arnous MM, Liu Q, Zhang Y, Lan X.
    Mol Pharm; 2019 Nov 04; 16(11):4563-4571. PubMed ID: 31553879
    [Abstract] [Full Text] [Related]

  • 20. Dietary isoflavone daidzein synergizes centchroman action via induction of apoptosis and inhibition of PI3K/Akt pathway in MCF-7/MDA MB-231 human breast cancer cells.
    Kaushik S, Shyam H, Sharma R, Balapure AK.
    Phytomedicine; 2018 Feb 01; 40():116-124. PubMed ID: 29496164
    [Abstract] [Full Text] [Related]

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