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159 related items for PubMed ID: 37451147
1. Discovery of novel 2-(trifluoromethyl)quinolin-4-amine derivatives as potent antitumor agents with microtubule polymerization inhibitory activity. Liu K, Mo M, Yu G, Yu J, Song SM, Cheng S, Li HM, Meng XL, Zeng XP, Xu GC, Luo H, Xu BX. Bioorg Chem; 2023 Oct; 139():106727. PubMed ID: 37451147 [Abstract] [Full Text] [Related]
2. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation. Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH. J Enzyme Inhib Med Chem; 2021 Dec; 36(1):640-658. PubMed ID: 33588683 [Abstract] [Full Text] [Related]
3. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site. Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM. Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238 [Abstract] [Full Text] [Related]
4. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway. Song J, Wang SH, Song CH, Zhang WX, Zhu JX, Tian XY, Fu XJ, Xu Y, Jin CY, Zhang SY. Eur J Med Chem; 2022 Oct 05; 240():114583. PubMed ID: 35834904 [Abstract] [Full Text] [Related]
5. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors. Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R. Arch Pharm (Weinheim); 2019 Jun 05; 352(6):e1800307. PubMed ID: 31012156 [Abstract] [Full Text] [Related]
6. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect. Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM. J Enzyme Inhib Med Chem; 2021 Dec 05; 36(1):802-818. PubMed ID: 33730937 [Abstract] [Full Text] [Related]
7. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities. Ren Y, Ruan Y, Cheng B, Li L, Liu J, Fang Y, Chen J. Bioorg Med Chem; 2021 Sep 15; 46():116376. PubMed ID: 34455231 [Abstract] [Full Text] [Related]
8. Discovery of novel N-aryl-2-trifluoromethyl-quinazoline-4-amine derivatives as the inhibitors of tubulin polymerization in leukemia cells. Wu H, Wang LS, Li P, Yu J, Cheng S, Yu G, Ahmad M, Meng XL, Luo H, Xu BX. Eur J Med Chem; 2023 Aug 05; 256():115470. PubMed ID: 37201429 [Abstract] [Full Text] [Related]
9. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance. Liu Z, Yang Z, Ablise M. Bioorg Chem; 2024 Jun 05; 147():107310. PubMed ID: 38583249 [Abstract] [Full Text] [Related]
10. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition. Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G. Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790 [Abstract] [Full Text] [Related]
11. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines. Huo XS, Jian XE, Ou-Yang J, Chen L, Yang F, Lv DX, You WW, Rao JJ, Zhao PL. Eur J Med Chem; 2021 Aug 05; 220():113449. PubMed ID: 33895499 [Abstract] [Full Text] [Related]
12. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities. Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY. Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875 [Abstract] [Full Text] [Related]
13. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines. Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S. Anticancer Agents Med Chem; 2021 Feb 05; 21(8):1047-1055. PubMed ID: 32981511 [Abstract] [Full Text] [Related]
14. Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin. Sharma A, Sáez-Calvo G, Olieric N, de Asís Balaguer F, Barasoain I, Lamberth C, Díaz JF, Steinmetz MO. Int J Mol Sci; 2017 Jun 22; 18(7):. PubMed ID: 28640209 [Abstract] [Full Text] [Related]
15. New Combretastatin Analogs as Anticancer Agents: Design, Synthesis, Microtubules Polymerization Inhibition, and Molecular Docking Studies. Abdul Hussein SA, Razzak Mahmood AA, Tahtamouni LH, Balakit AA, Yaseen YS, Al-Hasani RA. Chem Biodivers; 2023 Apr 22; 20(4):e202201206. PubMed ID: 36890635 [Abstract] [Full Text] [Related]
16. Design, synthesis and bioevaluation of novel trifluoromethylquinoline derivatives as tubulin polymerization inhibitors. Zhang S, Mo M, Lv M, Xia W, Liu K, Yu G, Yu J, Xu G, Zeng X, Cheng S, Xu B, Luo H, Meng X. Future Med Chem; 2023 Nov 22; 15(21):1967-1986. PubMed ID: 37937524 [Abstract] [Full Text] [Related]
17. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors. Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL. Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234 [Abstract] [Full Text] [Related]
18. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance. Cheng B, Zhu G, Meng L, Wu G, Chen Q, Ma S. Eur J Med Chem; 2022 Jan 15; 228():113930. PubMed ID: 34794817 [Abstract] [Full Text] [Related]
19. Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site. Li W, Shuai W, Sun H, Xu F, Bi Y, Xu J, Ma C, Yao H, Zhu Z, Xu S. Eur J Med Chem; 2019 Feb 01; 163():428-442. PubMed ID: 30530194 [Abstract] [Full Text] [Related]
20. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo. Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP. Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012 [Abstract] [Full Text] [Related] Page: [Next] [New Search]