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282 related items for PubMed ID: 3745439

  • 1. Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.
    Drapier JC, Hibbs JB.
    J Clin Invest; 1986 Sep; 78(3):790-7. PubMed ID: 3745439
    [Abstract] [Full Text] [Related]

  • 2. Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells.
    Drapier JC, Hibbs JB.
    J Immunol; 1988 Apr 15; 140(8):2829-38. PubMed ID: 2451695
    [Abstract] [Full Text] [Related]

  • 3. Monokine mediated release of intracellular iron in tumor target cells in vitro.
    Klostergaard J.
    Lymphokine Res; 1987 Apr 15; 6(1):19-28. PubMed ID: 3546962
    [Abstract] [Full Text] [Related]

  • 4. L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.
    Hibbs JB, Vavrin Z, Taintor RR.
    J Immunol; 1987 Jan 15; 138(2):550-65. PubMed ID: 2432129
    [Abstract] [Full Text] [Related]

  • 5. Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity.
    Bulteau AL, O'Neill HA, Kennedy MC, Ikeda-Saito M, Isaya G, Szweda LI.
    Science; 2004 Jul 09; 305(5681):242-5. PubMed ID: 15247478
    [Abstract] [Full Text] [Related]

  • 6. Tumoricidal effector mechanisms of murine Bacillus Calmette-Guérin-activated macrophages: mediation of cytolysis, mitochondrial respiration inhibition, and release of intracellular iron by distinct mechanisms.
    Klostergaard J, Leroux ME, Ezell SM, Kull FC.
    Cancer Res; 1987 Apr 15; 47(8):2014-9. PubMed ID: 3828989
    [Abstract] [Full Text] [Related]

  • 7. Metabolic regulation of citrate and iron by aconitases: role of iron-sulfur cluster biogenesis.
    Tong WH, Rouault TA.
    Biometals; 2007 Jun 15; 20(3-4):549-64. PubMed ID: 17205209
    [Abstract] [Full Text] [Related]

  • 8. Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione.
    Han D, Canali R, Garcia J, Aguilera R, Gallaher TK, Cadenas E.
    Biochemistry; 2005 Sep 13; 44(36):11986-96. PubMed ID: 16142896
    [Abstract] [Full Text] [Related]

  • 9. Nitric oxide and peroxynitrite-dependent aconitase inactivation and iron-regulatory protein-1 activation in mammalian fibroblasts.
    Castro LA, Robalinho RL, Cayota A, Meneghini R, Radi R.
    Arch Biochem Biophys; 1998 Nov 15; 359(2):215-24. PubMed ID: 9808763
    [Abstract] [Full Text] [Related]

  • 10. Mössbauer and EPR studies of activated aconitase: development of a localized valence state at a subsite of the [4Fe-4S] cluster on binding of citrate.
    Emptage MH, Kent TA, Kennedy MC, Beinert H, Münck E.
    Proc Natl Acad Sci U S A; 1983 Aug 15; 80(15):4674-8. PubMed ID: 6308639
    [Abstract] [Full Text] [Related]

  • 11. Interplay between NO and [Fe-S] clusters: relevance to biological systems.
    Drapier JC.
    Methods; 1997 Mar 15; 11(3):319-29. PubMed ID: 9073575
    [Abstract] [Full Text] [Related]

  • 12. Mitochondrial iron loss from leukemia cells injured by macrophages. A possible mechanism for electron transport chain defects.
    Wharton M, Granger DL, Durack DT.
    J Immunol; 1988 Aug 15; 141(4):1311-7. PubMed ID: 3397540
    [Abstract] [Full Text] [Related]

  • 13. Evidence for the formation of a linear [3Fe-4S] cluster in partially unfolded aconitase.
    Kennedy MC, Kent TA, Emptage M, Merkle H, Beinert H, Münck E.
    J Biol Chem; 1984 Dec 10; 259(23):14463-71. PubMed ID: 6094558
    [Abstract] [Full Text] [Related]

  • 14. Redox-dependent modulation of aconitase activity in intact mitochondria.
    Bulteau AL, Ikeda-Saito M, Szweda LI.
    Biochemistry; 2003 Dec 23; 42(50):14846-55. PubMed ID: 14674759
    [Abstract] [Full Text] [Related]

  • 15. In vitro activation of apo-aconitase using a [4Fe-4S] cluster-loaded form of the IscU [Fe-S] cluster scaffolding protein.
    Unciuleac MC, Chandramouli K, Naik S, Mayer S, Huynh BH, Johnson MK, Dean DR.
    Biochemistry; 2007 Jun 12; 46(23):6812-21. PubMed ID: 17506526
    [Abstract] [Full Text] [Related]

  • 16. Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells.
    Chen H, Davidson T, Singleton S, Garrick MD, Costa M.
    Toxicol Appl Pharmacol; 2005 Aug 15; 206(3):275-87. PubMed ID: 16039939
    [Abstract] [Full Text] [Related]

  • 17. Hyperthermic modulation of respiratory inhibition factor- and iron releasing factor-dependent macrophage murine tumor cytotoxicity.
    Klostergaard J, Barta M, Tomasovic SP.
    Cancer Res; 1989 Nov 15; 49(22):6252-7. PubMed ID: 2680061
    [Abstract] [Full Text] [Related]

  • 18. Mössbauer studies of aconitase. Substrate and inhibitor binding, reaction intermediates, and hyperfine interactions of reduced 3Fe and 4Fe clusters.
    Kent TA, Emptage MH, Merkle H, Kennedy MC, Beinert H, Münck E.
    J Biol Chem; 1985 Jun 10; 260(11):6871-81. PubMed ID: 2987236
    [Abstract] [Full Text] [Related]

  • 19. Nitric oxide and peroxynitrite activate the iron regulatory protein-1 of J774A.1 macrophages by direct disassembly of the Fe-S cluster of cytoplasmic aconitase.
    Cairo G, Ronchi R, Recalcati S, Campanella A, Minotti G.
    Biochemistry; 2002 Jun 11; 41(23):7435-42. PubMed ID: 12044177
    [Abstract] [Full Text] [Related]

  • 20. Leishmania spp.: nitric oxide-mediated metabolic inhibition of promastigote and axenically grown amastigote forms.
    Lemesre JL, Sereno D, Daulouède S, Veyret B, Brajon N, Vincendeau P.
    Exp Parasitol; 1997 May 11; 86(1):58-68. PubMed ID: 9149241
    [Abstract] [Full Text] [Related]

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