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Journal Abstract Search

218 related items for PubMed ID: 37490552

  • 1. Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
    Zhao X, Guo B, Sun W, Yu J, Cui L.
    Adv Sci (Weinh); 2023 Sep; 10(27):e2206878. PubMed ID: 37490552
    [Abstract] [Full Text] [Related]

  • 2. ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
    Cui L, Lu Y, Zheng J, Guo B, Zhao X.
    J Exp Clin Cancer Res; 2023 Dec 07; 42(1):335. PubMed ID: 38057867
    [Abstract] [Full Text] [Related]

  • 3. Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
    Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J.
    Int J Biol Sci; 2022 Dec 07; 18(9):3576-3591. PubMed ID: 35813482
    [Abstract] [Full Text] [Related]

  • 4. Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index.
    Wang Y, Ma X, Xu E, Huang Z, Yang C, Zhu K, Dong Y, Zhang C.
    Clin Transl Med; 2024 Feb 07; 14(2):e1586. PubMed ID: 38372422
    [Abstract] [Full Text] [Related]

  • 5. Squalene epoxidase promotes the chemoresistance of colorectal cancer via (S)-2,3-epoxysqualene-activated NF-κB.
    Liu Q, Zhang Y, Li H, Gao H, Zhou Y, Luo D, Shan Z, Yang Y, Weng J, Li Q, Yang W, Li X.
    Cell Commun Signal; 2024 May 18; 22(1):278. PubMed ID: 38762737
    [Abstract] [Full Text] [Related]

  • 6. Reduction of Squalene Epoxidase by Cholesterol Accumulation Accelerates Colorectal Cancer Progression and Metastasis.
    Jun SY, Brown AJ, Chua NK, Yoon JY, Lee JJ, Yang JO, Jang I, Jeon SJ, Choi TI, Kim CH, Kim NS.
    Gastroenterology; 2021 Mar 18; 160(4):1194-1207.e28. PubMed ID: 32946903
    [Abstract] [Full Text] [Related]

  • 7. Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with p53 mutation and elevated c-MYC expression.
    Du Y, Rokavec M, Hermeking H.
    Int J Biol Sci; 2023 Mar 18; 19(13):4103-4122. PubMed ID: 37705742
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of squalene epoxidase linking with PI3K/AKT signaling pathway suppresses endometrial cancer.
    Ma L, Huang W, Liang X, Bai G, Wang X, Jiang H, Xin Y, Hu L, Chen X, Liu C.
    Cancer Sci; 2023 Sep 18; 114(9):3595-3607. PubMed ID: 37438885
    [Abstract] [Full Text] [Related]

  • 9. Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target.
    Liu D, Wong CC, Zhou Y, Li C, Chen H, Ji F, Go MYY, Wang F, Su H, Wei H, Cai Z, Wong N, Wong VWS, Yu J.
    Gastroenterology; 2021 Jun 18; 160(7):2467-2482.e3. PubMed ID: 33647280
    [Abstract] [Full Text] [Related]

  • 10. Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma.
    Liu S, Qin Z, Mao Y, Wang N, Zhang W, Wang Y, Chen Y, Jia L, Peng X.
    Theranostics; 2024 Jun 18; 14(2):622-639. PubMed ID: 38169606
    [Abstract] [Full Text] [Related]

  • 11. SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
    Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y.
    Cell Death Dis; 2023 Aug 04; 14(8):497. PubMed ID: 37542052
    [Abstract] [Full Text] [Related]

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  • 13. Squalene epoxidase-induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling.
    Li L, Zhang Q, Wang X, Li Y, Xie H, Chen X.
    Cancer Sci; 2020 Jul 04; 111(7):2275-2283. PubMed ID: 32314495
    [Abstract] [Full Text] [Related]

  • 14. TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling.
    Xu T, Yang Y, Chen Z, Wang J, Wang X, Zheng Y, Wang C, Wang Y, Zhu Z, Ding X, Zhou J, Li G, Zhang H, Zhang W, Wu Y, Song X.
    J Exp Clin Cancer Res; 2023 Aug 01; 42(1):190. PubMed ID: 37525222
    [Abstract] [Full Text] [Related]

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  • 17. Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness.
    Jing C, Duan Y, Zhou M, Yue K, Zhuo S, Li X, Liu D, Ye B, Lai Q, Li L, Yao X, Wei H, Zhang W, Wu Y, Wang X.
    Theranostics; 2021 Aug 01; 11(6):2655-2669. PubMed ID: 33456565
    [Abstract] [Full Text] [Related]

  • 18. Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
    Li C, Wang Y, Liu D, Wong CC, Coker OO, Zhang X, Liu C, Zhou Y, Liu Y, Kang W, To KF, Sung JJ, Yu J.
    Gut; 2022 Nov 01; 71(11):2253-2265. PubMed ID: 35232776
    [Abstract] [Full Text] [Related]

  • 19. The Polo-like kinase 1 inhibitor onvansertib represents a relevant treatment for head and neck squamous cell carcinoma resistant to cisplatin and radiotherapy.
    Hagege A, Ambrosetti D, Boyer J, Bozec A, Doyen J, Chamorey E, He X, Bourget I, Rousset J, Saada E, Rastoin O, Parola J, Luciano F, Cao Y, Pagès G, Dufies M.
    Theranostics; 2021 Nov 01; 11(19):9571-9586. PubMed ID: 34646387
    [Abstract] [Full Text] [Related]

  • 20. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
    Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A.
    Nat Commun; 2021 Aug 20; 12(1):5066. PubMed ID: 34417456
    [Abstract] [Full Text] [Related]

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