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137 related items for PubMed ID: 37490761

  • 1. Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
    Erwin K, Moreno RY, Baas BJ, Zhang YJ, Whitman CP.
    Biochemistry; 2023 Aug 15; 62(16):2461-2471. PubMed ID: 37490761
    [Abstract] [Full Text] [Related]

  • 2. Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
    Medellin BP, Lancaster EB, Brown SD, Rakhade S, Babbitt PC, Whitman CP, Zhang YJ.
    Biochemistry; 2020 Apr 28; 59(16):1592-1603. PubMed ID: 32242662
    [Abstract] [Full Text] [Related]

  • 3. Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
    Baas BJ, Medellin BP, LeVieux JA, de Ruijter M, Zhang YJ, Brown SD, Akiva E, Babbitt PC, Whitman CP.
    Biochemistry; 2019 Jun 04; 58(22):2617-2627. PubMed ID: 31074977
    [Abstract] [Full Text] [Related]

  • 4. Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications.
    Baas BJ, Medellin BP, LeVieux JA, Erwin K, Lancaster EB, Johnson WH, Kaoud TS, Moreno RY, de Ruijter M, Babbitt PC, Zhang YJ, Whitman CP.
    Biochemistry; 2021 Jun 08; 60(22):1776-1786. PubMed ID: 34019384
    [Abstract] [Full Text] [Related]

  • 5. Kinetic and structural characterization of a heterohexamer 4-oxalocrotonate tautomerase from Chloroflexus aurantiacus J-10-fl: implications for functional and structural diversity in the tautomerase superfamily .
    Burks EA, Fleming CD, Mesecar AD, Whitman CP, Pegan SD.
    Biochemistry; 2010 Jun 22; 49(24):5016-27. PubMed ID: 20465238
    [Abstract] [Full Text] [Related]

  • 6. The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif.
    Whitman CP.
    Arch Biochem Biophys; 2002 Jun 01; 402(1):1-13. PubMed ID: 12051677
    [Abstract] [Full Text] [Related]

  • 7. Symmetry of 4-Oxalocrotonate Tautomerase Trimers Influences Unfolding and Fragmentation in the Gas Phase.
    Sipe SN, Lancaster EB, Butalewicz JP, Whitman CP, Brodbelt JS.
    J Am Chem Soc; 2022 Jul 13; 144(27):12299-12309. PubMed ID: 35767842
    [Abstract] [Full Text] [Related]

  • 8. Gene Fusion and Directed Evolution to Break Structural Symmetry and Boost Catalysis by an Oligomeric C-C Bond-Forming Enzyme.
    Xu G, Kunzendorf A, Crotti M, Rozeboom HJ, Thunnissen AWH, Poelarends GJ.
    Angew Chem Int Ed Engl; 2022 Feb 14; 61(8):e202113970. PubMed ID: 34890491
    [Abstract] [Full Text] [Related]

  • 9. Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomerase.
    Poelarends GJ, Almrud JJ, Serrano H, Darty JE, Johnson WH, Hackert ML, Whitman CP.
    Biochemistry; 2006 Jun 27; 45(25):7700-8. PubMed ID: 16784221
    [Abstract] [Full Text] [Related]

  • 10. Identification and characterization of new family members in the tautomerase superfamily: analysis and implications.
    Huddleston JP, Burks EA, Whitman CP.
    Arch Biochem Biophys; 2014 Dec 15; 564():189-96. PubMed ID: 25219626
    [Abstract] [Full Text] [Related]

  • 11. Cloning, expression, and characterization of a cis-3-chloroacrylic acid dehalogenase: insights into the mechanistic, structural, and evolutionary relationship between isomer-specific 3-chloroacrylic acid dehalogenases.
    Poelarends GJ, Serrano H, Person MD, Johnson WH, Murzin AG, Whitman CP.
    Biochemistry; 2004 Jan 27; 43(3):759-72. PubMed ID: 14730981
    [Abstract] [Full Text] [Related]

  • 12. trans-3-Chloroacrylic acid dehalogenase from Pseudomonas pavonaceae 170 shares structural and mechanistic similarities with 4-oxalocrotonate tautomerase.
    Poelarends GJ, Saunier R, Janssen DB.
    J Bacteriol; 2001 Jul 27; 183(14):4269-77. PubMed ID: 11418568
    [Abstract] [Full Text] [Related]

  • 13. The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.
    Czerwinski RM, Harris TK, Massiah MA, Mildvan AS, Whitman CP.
    Biochemistry; 2001 Feb 20; 40(7):1984-95. PubMed ID: 11329265
    [Abstract] [Full Text] [Related]

  • 14. Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members.
    Almrud JJ, Dasgupta R, Czerwinski RM, Kern AD, Hackert ML, Whitman CP.
    Bioorg Chem; 2010 Dec 20; 38(6):252-9. PubMed ID: 20709352
    [Abstract] [Full Text] [Related]

  • 15. Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase.
    Harris TK, Czerwinski RM, Johnson WH, Legler PM, Abeygunawardana C, Massiah MA, Stivers JT, Whitman CP, Mildvan AS.
    Biochemistry; 1999 Sep 21; 38(38):12343-57. PubMed ID: 10493802
    [Abstract] [Full Text] [Related]

  • 16. Kinetic, crystallographic, and mechanistic characterization of TomN: elucidation of a function for a 4-oxalocrotonate tautomerase homologue in the tomaymycin biosynthetic pathway.
    Burks EA, Yan W, Johnson WH, Li W, Schroeder GK, Min C, Gerratana B, Zhang Y, Whitman CP.
    Biochemistry; 2011 Sep 06; 50(35):7600-11. PubMed ID: 21809870
    [Abstract] [Full Text] [Related]

  • 17. Structural and kinetic characterization of two 4-oxalocrotonate tautomerases in Methylibium petroleiphilum strain PM1.
    Terrell CR, Burks EA, Whitman CP, Hoffman DW.
    Arch Biochem Biophys; 2013 Sep 01; 537(1):113-24. PubMed ID: 23831510
    [Abstract] [Full Text] [Related]

  • 18. Systematic screening for catalytic promiscuity in 4-oxalocrotonate tautomerase: enamine formation and aldolase activity.
    Zandvoort E, Baas BJ, Quax WJ, Poelarends GJ.
    Chembiochem; 2011 Mar 07; 12(4):602-9. PubMed ID: 21290551
    [Abstract] [Full Text] [Related]

  • 19. 4-Oxalocrotonate tautomerase, a 41-kDa homohexamer: backbone and side-chain resonance assignments, solution secondary structure, and location of active site residues by heteronuclear NMR spectroscopy.
    Stivers JT, Abeygunawardana C, Whitman CP, Mildvan AS.
    Protein Sci; 1996 Apr 07; 5(4):729-41. PubMed ID: 8845763
    [Abstract] [Full Text] [Related]

  • 20. The crystal structure of YdcE, a 4-oxalocrotonate tautomerase homologue from Escherichia coli, confirms the structural basis for oligomer diversity.
    Almrud JJ, Kern AD, Wang SC, Czerwinski RM, Johnson WH, Murzin AG, Hackert ML, Whitman CP.
    Biochemistry; 2002 Oct 08; 41(40):12010-24. PubMed ID: 12356301
    [Abstract] [Full Text] [Related]

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