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368 related items for PubMed ID: 37491315

  • 1. Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiation in Vivo.
    Ondrejcak T, Klyubin I, Hu NW, O'Malley TT, Corbett GT, Winters R, Perkinton MS, Billinton A, Prenderville JA, Walsh DM, Rowan MJ.
    J Neurosci; 2023 Aug 09; 43(32):5870-5879. PubMed ID: 37491315
    [Abstract] [Full Text] [Related]

  • 2. Rapidly reversible persistent long-term potentiation inhibition by patient-derived brain tau and amyloid ß proteins.
    Ondrejcak T, Klyubin I, Hu NW, Yang Y, Zhang Q, Rodriguez BJ, Rowan MJ.
    Philos Trans R Soc Lond B Biol Sci; 2024 Jul 29; 379(1906):20230234. PubMed ID: 38853565
    [Abstract] [Full Text] [Related]

  • 3. Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo.
    Ondrejcak T, Klyubin I, Corbett GT, Fraser G, Hong W, Mably AJ, Gardener M, Hammersley J, Perkinton MS, Billinton A, Walsh DM, Rowan MJ.
    J Neurosci; 2018 Dec 12; 38(50):10595-10606. PubMed ID: 30355631
    [Abstract] [Full Text] [Related]

  • 4. Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer's disease.
    Li S, Jin M, Liu L, Dang Y, Ostaszewski BL, Selkoe DJ.
    Acta Neuropathol Commun; 2018 Nov 08; 6(1):121. PubMed ID: 30409172
    [Abstract] [Full Text] [Related]

  • 5. Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.
    Wang Z, Jackson RJ, Hong W, Taylor WM, Corbett GT, Moreno A, Liu W, Li S, Frosch MP, Slutsky I, Young-Pearse TL, Spires-Jones TL, Walsh DM.
    J Neurosci; 2017 Dec 06; 37(49):11947-11966. PubMed ID: 29101243
    [Abstract] [Full Text] [Related]

  • 6. Soluble tau aggregates inhibit synaptic long-term depression and amyloid β-facilitated LTD in vivo.
    Ondrejcak T, Hu NW, Qi Y, Klyubin I, Corbett GT, Fraser G, Perkinton MS, Walsh DM, Billinton A, Rowan MJ.
    Neurobiol Dis; 2019 Jul 06; 127():582-590. PubMed ID: 30910746
    [Abstract] [Full Text] [Related]

  • 7. Patient-derived tau and amyloid-β facilitate long-term depression in vivo: role of tumour necrosis factor-α and the integrated stress response.
    Hu NW, Ondrejcak T, Klyubin I, Yang Y, Walsh DM, Livesey FJ, Rowan MJ.
    Brain Commun; 2024 Jul 06; 6(5):fcae333. PubMed ID: 39391333
    [Abstract] [Full Text] [Related]

  • 8. Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
    Yang T, Li S, Xu H, Walsh DM, Selkoe DJ.
    J Neurosci; 2017 Jan 04; 37(1):152-163. PubMed ID: 28053038
    [Abstract] [Full Text] [Related]

  • 9. Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo.
    Klyubin I, Ondrejcak T, Hayes J, Cullen WK, Mably AJ, Walsh DM, Rowan MJ.
    Philos Trans R Soc Lond B Biol Sci; 2014 Jan 05; 369(1633):20130147. PubMed ID: 24298149
    [Abstract] [Full Text] [Related]

  • 10. Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.
    Barry AE, Klyubin I, Mc Donald JM, Mably AJ, Farrell MA, Scott M, Walsh DM, Rowan MJ.
    J Neurosci; 2011 May 18; 31(20):7259-63. PubMed ID: 21593310
    [Abstract] [Full Text] [Related]

  • 11. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
    Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ.
    Nat Med; 2008 Aug 18; 14(8):837-42. PubMed ID: 18568035
    [Abstract] [Full Text] [Related]

  • 12. Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity.
    Hu NW, Corbett GT, Moore S, Klyubin I, O'Malley TT, Walsh DM, Livesey FJ, Rowan MJ.
    Cell Rep; 2018 May 15; 23(7):1932-1938. PubMed ID: 29768194
    [Abstract] [Full Text] [Related]

  • 13. Simvastatin treatment preserves synaptic plasticity in AβPPswe/PS1dE9 mice.
    Métais C, Brennan K, Mably AJ, Scott M, Walsh DM, Herron CE.
    J Alzheimers Dis; 2014 May 15; 39(2):315-29. PubMed ID: 24164738
    [Abstract] [Full Text] [Related]

  • 14. Systematic characterization of a non-transgenic Aβ1-42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice.
    Jiménez-Herrera R, Contreras A, Djebari S, Mulero-Franco J, Iborra-Lázaro G, Jeremic D, Navarro-López J, Jiménez-Díaz L.
    Biol Sex Differ; 2023 Sep 16; 14(1):59. PubMed ID: 37716988
    [Abstract] [Full Text] [Related]

  • 15. Tau is not necessary for amyloid-β-induced synaptic and memory impairments.
    Puzzo D, Argyrousi EK, Staniszewski A, Zhang H, Calcagno E, Zuccarello E, Acquarone E, Fa' M, Li Puma DD, Grassi C, D'Adamio L, Kanaan NM, Fraser PE, Arancio O.
    J Clin Invest; 2020 Sep 01; 130(9):4831-4844. PubMed ID: 32544084
    [Abstract] [Full Text] [Related]

  • 16. Synaptic Mitochondria: An Early Target of Amyloid-β and Tau in Alzheimer's Disease.
    Torres AK, Jara C, Park-Kang HS, Polanco CM, Tapia D, Alarcón F, de la Peña A, Llanquinao J, Vargas-Mardones G, Indo JA, Inestrosa NC, Tapia-Rojas C.
    J Alzheimers Dis; 2021 Sep 01; 84(4):1391-1414. PubMed ID: 34719499
    [Abstract] [Full Text] [Related]

  • 17. CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer's Disease.
    Shentu YP, Huo Y, Feng XL, Gilbert J, Zhang Q, Liuyang ZY, Wang XL, Wang G, Zhou H, Wang XC, Wang JZ, Lu YM, Westermarck J, Man HY, Liu R.
    Cell Rep; 2018 Jul 17; 24(3):713-723. PubMed ID: 30021167
    [Abstract] [Full Text] [Related]

  • 18. Synaptic changes in Alzheimer's disease and its models.
    Pozueta J, Lefort R, Shelanski ML.
    Neuroscience; 2013 Oct 22; 251():51-65. PubMed ID: 22687952
    [Abstract] [Full Text] [Related]

  • 19. Astrocytic glutamatergic transporters are involved in Aβ-induced synaptic dysfunction.
    Huang S, Tong H, Lei M, Zhou M, Guo W, Li G, Tang X, Li Z, Mo M, Zhang X, Chen X, Cen L, Wei L, Xiao Y, Li K, Huang Q, Yang X, Liu W, Zhang L, Qu S, Li S, Xu P.
    Brain Res; 2018 Jan 01; 1678():129-137. PubMed ID: 29066369
    [Abstract] [Full Text] [Related]

  • 20. Leptin prevents aberrant targeting of tau to hippocampal synapses via PI 3 kinase driven inhibition of GSK3β.
    Hamilton K, Morrow K, Markantoni E, Harvey J.
    J Neurochem; 2023 Nov 01; 167(4):520-537. PubMed ID: 37822142
    [Abstract] [Full Text] [Related]

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