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160 related items for PubMed ID: 3753976

  • 1. The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells.
    Stevens J, Hayden P, Taylor G.
    J Biol Chem; 1986 Mar 05; 261(7):3325-32. PubMed ID: 3753976
    [Abstract] [Full Text] [Related]

  • 2. Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
    Chen JC, Stevens JL, Trifillis AL, Jones TW.
    Toxicol Appl Pharmacol; 1990 May 05; 103(3):463-73. PubMed ID: 2339419
    [Abstract] [Full Text] [Related]

  • 3. Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.
    Elfarra AA, Jakobson I, Anders MW.
    Biochem Pharmacol; 1986 Jan 15; 35(2):283-8. PubMed ID: 2867768
    [Abstract] [Full Text] [Related]

  • 4. Mutagenicity of amino acid and glutathione S-conjugates in the Ames test.
    Vamvakas S, Elfarra AA, Dekant W, Henschler D, Anders MW.
    Mutat Res; 1988 Sep 15; 206(1):83-90. PubMed ID: 2901035
    [Abstract] [Full Text] [Related]

  • 5. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
    Lash LH, Sausen PJ, Duescher RJ, Cooley AJ, Elfarra AA.
    J Pharmacol Exp Ther; 1994 Apr 15; 269(1):374-83. PubMed ID: 8169843
    [Abstract] [Full Text] [Related]

  • 6. Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin.
    Zhang L, Hanigan MH.
    J Pharmacol Exp Ther; 2003 Sep 15; 306(3):988-94. PubMed ID: 12750429
    [Abstract] [Full Text] [Related]

  • 7. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
    McGoldrick TA, Lock EA, Rodilla V, Hawksworth GM.
    Arch Toxicol; 2003 Jul 15; 77(7):365-70. PubMed ID: 12700887
    [Abstract] [Full Text] [Related]

  • 8. Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells.
    Lash LH, Anders MW.
    J Biol Chem; 1986 Oct 05; 261(28):13076-81. PubMed ID: 2875994
    [Abstract] [Full Text] [Related]

  • 9. Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase.
    Stevens JL, Hatzinger PB, Hayden PJ.
    Drug Metab Dispos; 1989 Oct 05; 17(3):297-303. PubMed ID: 2568912
    [Abstract] [Full Text] [Related]

  • 10. Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine.
    Mertens JJ, Weijnen JG, van Doorn WJ, Spenkelink B, Temmink JH, van Bladeren PJ.
    Chem Biol Interact; 1988 Oct 05; 65(3):283-93. PubMed ID: 3378280
    [Abstract] [Full Text] [Related]

  • 11. Bacterial cysteine conjugate beta-lyase and the metabolism of cysteine S-conjugates: structural requirements for the cleavage of S-conjugates and the formation of reactive intermediates.
    Vamvakas S, Berthold K, Dekant W, Henschler D.
    Chem Biol Interact; 1988 Oct 05; 65(1):59-71. PubMed ID: 3278814
    [Abstract] [Full Text] [Related]

  • 12. L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?
    Cooper AJ, Krasnikov BF, Okuno E, Jeitner TM.
    Biochem J; 2003 Nov 15; 376(Pt 1):169-78. PubMed ID: 12859250
    [Abstract] [Full Text] [Related]

  • 13. The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation.
    Chen Q, Jones TW, Brown PC, Stevens JL.
    J Biol Chem; 1990 Dec 15; 265(35):21603-11. PubMed ID: 2254317
    [Abstract] [Full Text] [Related]

  • 14. Metabolism of Cisplatin to a nephrotoxin in proximal tubule cells.
    Townsend DM, Deng M, Zhang L, Lapus MG, Hanigan MH.
    J Am Soc Nephrol; 2003 Jan 15; 14(1):1-10. PubMed ID: 12506132
    [Abstract] [Full Text] [Related]

  • 15. The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates.
    Stevens JL, Ayoubi N, Robbins JD.
    J Biol Chem; 1988 Mar 05; 263(7):3395-401. PubMed ID: 3343250
    [Abstract] [Full Text] [Related]

  • 16. Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation.
    Cooper AJ, Bruschi SA, Conway M, Hutson SM.
    Biochem Pharmacol; 2003 Jan 15; 65(2):181-92. PubMed ID: 12504794
    [Abstract] [Full Text] [Related]

  • 17. Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules.
    Zhang GH, Stevens JL.
    Toxicol Appl Pharmacol; 1989 Aug 15; 100(1):51-61. PubMed ID: 2763302
    [Abstract] [Full Text] [Related]

  • 18. Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells.
    Cummings BS, Lash LH.
    Toxicol Sci; 2000 Feb 15; 53(2):458-66. PubMed ID: 10696794
    [Abstract] [Full Text] [Related]

  • 19. High-performance liquid chromatography-fluorescence assay of pyruvic acid to determine cysteine conjugate beta-lyase activity: application to S-1,2-dichlorovinyl-L-cysteine and S-2-benzothiazolyl-L-cysteine.
    Stijntjes GJ, te Koppele JM, Vermeulen NP.
    Anal Biochem; 1992 Nov 01; 206(2):334-43. PubMed ID: 1443603
    [Abstract] [Full Text] [Related]

  • 20. Role of renal cysteine conjugate beta-lyase in the mechanism of compound A nephrotoxicity in rats.
    Kharasch ED, Thorning D, Garton K, Hankins DC, Kilty CG.
    Anesthesiology; 1997 Jan 01; 86(1):160-71. PubMed ID: 9009951
    [Abstract] [Full Text] [Related]

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