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142 related items for PubMed ID: 37552875

  • 1. An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets.
    Keller MP, Hawes EM, Schueler KL, Stapleton DS, Mitok KA, Simonett SP, Oeser JK, Sampson LL, Attie AD, Magnuson MA, O'Brien RM.
    Diabetes; 2023 Nov 01; 72(11):1621-1628. PubMed ID: 37552875
    [Abstract] [Full Text] [Related]

  • 2. Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose.
    Bosma KJ, Rahim M, Singh K, Goleva SB, Wall ML, Xia J, Syring KE, Oeser JK, Poffenberger G, McGuinness OP, Means AL, Powers AC, Li WH, Davis LK, Young JD, O'Brien RM.
    J Mol Endocrinol; 2020 May 01; 64(4):235-248. PubMed ID: 32213654
    [Abstract] [Full Text] [Related]

  • 3. G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting.
    Bosma KJ, Rahim M, Oeser JK, McGuinness OP, Young JD, O'Brien RM.
    Mol Metab; 2020 Nov 01; 41():101043. PubMed ID: 32569842
    [Abstract] [Full Text] [Related]

  • 4. G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.
    Boortz KA, Syring KE, Dai C, Pound LD, Oeser JK, Jacobson DA, Wang JC, McGuinness OP, Powers AC, O'Brien RM.
    Endocrinology; 2016 Aug 01; 157(8):3002-8. PubMed ID: 27300767
    [Abstract] [Full Text] [Related]

  • 5. Multiple promoter and enhancer differences likely contribute to augmented G6PC2 expression in human versus mouse pancreatic islet alpha cells.
    Martin CC, Oeser JK, Wangmo T, Flemming BP, Attie AD, Keller MP, O'Brien RM.
    J Mol Endocrinol; 2024 Oct 01; 73(3):. PubMed ID: 39121091
    [Abstract] [Full Text] [Related]

  • 6. G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.
    Boortz KA, Syring KE, Lee RA, Dai C, Oeser JK, McGuinness OP, Wang JC, O'Brien RM.
    Endocrinology; 2016 Nov 01; 157(11):4133-4145. PubMed ID: 27653037
    [Abstract] [Full Text] [Related]

  • 7. Novel stable isotope analyses demonstrate significant rates of glucose cycling in mouse pancreatic islets.
    Wall ML, Pound LD, Trenary I, O'Brien RM, Young JD.
    Diabetes; 2015 Jun 01; 64(6):2129-37. PubMed ID: 25552595
    [Abstract] [Full Text] [Related]

  • 8. Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells.
    Rahim M, Nakhe AY, Banerjee DR, Overway EM, Bosma KJ, Rosch JC, Oeser JK, Wang B, Lippmann ES, Jacobson DA, O'Brien RM, Young JD.
    J Biol Chem; 2022 Apr 01; 298(4):101729. PubMed ID: 35176280
    [Abstract] [Full Text] [Related]

  • 9. G6PC2: a negative regulator of basal glucose-stimulated insulin secretion.
    Pound LD, Oeser JK, O'Brien TP, Wang Y, Faulman CJ, Dadi PK, Jacobson DA, Hutton JC, McGuinness OP, Shiota M, O'Brien RM.
    Diabetes; 2013 May 01; 62(5):1547-56. PubMed ID: 23274894
    [Abstract] [Full Text] [Related]

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  • 11. Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose.
    Overway EM, Bosma KJ, Claxton DP, Oeser JK, Singh K, Breidenbach LB, Mchaourab HS, Davis LK, O'Brien RM.
    J Biol Chem; 2022 Feb 01; 298(2):101534. PubMed ID: 34954144
    [Abstract] [Full Text] [Related]

  • 12. Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.
    O'Brien RM.
    Curr Diab Rep; 2013 Dec 01; 13(6):768-77. PubMed ID: 24142592
    [Abstract] [Full Text] [Related]

  • 13. Haplotypes of the genes (GCK and G6PC2) underlying the glucose/glucose-6-phosphate cycle are associated with pancreatic beta cell glucose sensitivity in patients with newly diagnosed type 2 diabetes from the VNDS study (VNDS 11).
    Zusi C, Rinaldi E, Bonetti S, Boselli ML, Trabetti E, Malerba G, Bonora E, Bonadonna RC, Trombetta M.
    J Endocrinol Invest; 2021 Dec 01; 44(12):2567-2574. PubMed ID: 34128214
    [Abstract] [Full Text] [Related]

  • 14. Deletion of the G6pc2 gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein does not affect the progression or incidence of type 1 diabetes in NOD/ShiLtJ mice.
    Oeser JK, Parekh VV, Wang Y, Jegadeesh NK, Sarkar SA, Wong R, Lee CE, Pound LD, Hutton JC, Van Kaer L, O'Brien RM.
    Diabetes; 2011 Nov 01; 60(11):2922-7. PubMed ID: 21896930
    [Abstract] [Full Text] [Related]

  • 15. Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.
    Bouatia-Naji N, Bonnefond A, Baerenwald DA, Marchand M, Bugliani M, Marchetti P, Pattou F, Printz RL, Flemming BP, Umunakwe OC, Conley NL, Vaxillaire M, Lantieri O, Balkau B, Marre M, Lévy-Marchal C, Elliott P, Jarvelin MR, Meyre D, Dina C, Oeser JK, Froguel P, O'Brien RM.
    Diabetes; 2010 Oct 01; 59(10):2662-71. PubMed ID: 20622168
    [Abstract] [Full Text] [Related]

  • 16. Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression.
    Boortz KA, Syring KE, Pound LD, Wang Y, Oeser JK, O'Brien RM.
    PLoS One; 2016 Oct 01; 11(9):e0162439. PubMed ID: 27611587
    [Abstract] [Full Text] [Related]

  • 17. Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype.
    Wang Y, Martin CC, Oeser JK, Sarkar S, McGuinness OP, Hutton JC, O'Brien RM.
    Diabetologia; 2007 Apr 01; 50(4):774-8. PubMed ID: 17265032
    [Abstract] [Full Text] [Related]

  • 18. Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose.
    Li X, Shu YH, Xiang AH, Trigo E, Kuusisto J, Hartiala J, Swift AJ, Kawakubo M, Stringham HM, Bonnycastle LL, Lawrence JM, Laakso M, Allayee H, Buchanan TA, Watanabe RM.
    Diabetes; 2009 Dec 01; 58(12):2946-53. PubMed ID: 19741163
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