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172 related items for PubMed ID: 37574474

  • 1. Highly Sensitive Radioactivity-Based DNA 3'-Phosphatase Activity Assay for Polynucleotide Kinase 3'-Phosphatase.
    Chakraborty A, Hazra TK.
    Methods Mol Biol; 2023; 2701():39-54. PubMed ID: 37574474
    [Abstract] [Full Text] [Related]

  • 2. Site-specific acetylation of polynucleotide kinase 3'-phosphatase regulates its distinct role in DNA repair pathways.
    Islam A, Chakraborty A, Sarker AH, Aryal UK, Pan L, Sharma G, Boldogh I, Hazra T.
    Nucleic Acids Res; 2024 Mar 21; 52(5):2416-2433. PubMed ID: 38224455
    [Abstract] [Full Text] [Related]

  • 3. Repair of DNA strand gaps and nicks containing 3'-phosphate and 5'-hydroxyl termini by purified mammalian enzymes.
    Karimi-Busheri F, Lee J, Tomkinson AE, Weinfeld M.
    Nucleic Acids Res; 1998 Oct 01; 26(19):4395-400. PubMed ID: 9742240
    [Abstract] [Full Text] [Related]

  • 4. XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair.
    Whitehouse CJ, Taylor RM, Thistlethwaite A, Zhang H, Karimi-Busheri F, Lasko DD, Weinfeld M, Caldecott KW.
    Cell; 2001 Jan 12; 104(1):107-17. PubMed ID: 11163244
    [Abstract] [Full Text] [Related]

  • 5. The phosphatase activity of mammalian polynucleotide kinase takes precedence over its kinase activity in repair of single strand breaks.
    Dobson CJ, Allinson SL.
    Nucleic Acids Res; 2006 Jan 12; 34(8):2230-7. PubMed ID: 16648365
    [Abstract] [Full Text] [Related]

  • 6. Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast.
    Sanchez A, Gadaleta MC, Limbo O, Russell P.
    PLoS Genet; 2017 Sep 12; 13(9):e1007013. PubMed ID: 28922417
    [Abstract] [Full Text] [Related]

  • 7. Mechanism of RNA 2',3'-cyclic phosphate end healing by T4 polynucleotide kinase-phosphatase.
    Das U, Shuman S.
    Nucleic Acids Res; 2013 Jan 07; 41(1):355-65. PubMed ID: 23118482
    [Abstract] [Full Text] [Related]

  • 8. Site-specific acetylation of polynucleotide kinase 3'-phosphatase (PNKP) regulates its distinct role in DNA repair pathways.
    Islam A, Chakraborty A, Sarker AH, Aryal UK, Sharma G, Boldogh I, Hazra T.
    bioRxiv; 2023 Aug 16. PubMed ID: 37645927
    [Abstract] [Full Text] [Related]

  • 9. The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
    Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal SM, Neves-Carvalho A, Liu Y, Pandita RK, Hegde ML, Hegde PM, Boldogh I, Ashizawa T, Koeppen AH, Pandita TK, Maciel P, Sarkar PS, Hazra TK.
    PLoS Genet; 2015 Jan 16; 11(1):e1004749. PubMed ID: 25633985
    [Abstract] [Full Text] [Related]

  • 10. Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome.
    Mandal SM, Hegde ML, Chatterjee A, Hegde PM, Szczesny B, Banerjee D, Boldogh I, Gao R, Falkenberg M, Gustafsson CM, Sarkar PS, Hazra TK.
    J Biol Chem; 2012 Jan 20; 287(4):2819-29. PubMed ID: 22130663
    [Abstract] [Full Text] [Related]

  • 11. Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3'-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage.
    Jilani A, Ramotar D, Slack C, Ong C, Yang XM, Scherer SW, Lasko DD.
    J Biol Chem; 1999 Aug 20; 274(34):24176-86. PubMed ID: 10446192
    [Abstract] [Full Text] [Related]

  • 12. Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway.
    Audebert M, Salles B, Weinfeld M, Calsou P.
    J Mol Biol; 2006 Feb 17; 356(2):257-65. PubMed ID: 16364363
    [Abstract] [Full Text] [Related]

  • 13. Molecular characterization of Plasmodium falciparum putative polynucleotide kinase/phosphatase.
    Siribal S, Weinfeld M, Karimi-Busheri F, Mark Glover JN, Bernstein NK, Aceytuno D, Chavalitshewinkoon-Petmitr P.
    Mol Biochem Parasitol; 2011 Nov 17; 180(1):1-7. PubMed ID: 21821066
    [Abstract] [Full Text] [Related]

  • 14. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells.
    Hegde ML, Hazra TK, Mitra S.
    Cell Res; 2008 Jan 17; 18(1):27-47. PubMed ID: 18166975
    [Abstract] [Full Text] [Related]

  • 15. Chromatin 3'-phosphatase/5'-OH kinase cannot transfer phosphate from 3' to 5' across a strand nick in DNA.
    Habraken Y, Verly WG.
    Nucleic Acids Res; 1986 Oct 24; 14(20):8103-10. PubMed ID: 3022244
    [Abstract] [Full Text] [Related]

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  • 17. Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
    Chakraborty A, Tapryal N, Venkova T, Mitra J, Vasquez V, Sarker AH, Duarte-Silva S, Huai W, Ashizawa T, Ghosh G, Maciel P, Sarkar PS, Hegde ML, Chen X, Hazra TK.
    Proc Natl Acad Sci U S A; 2020 Apr 07; 117(14):8154-8165. PubMed ID: 32205441
    [Abstract] [Full Text] [Related]

  • 18. Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining.
    Mani RS, Yu Y, Fang S, Lu M, Fanta M, Zolner AE, Tahbaz N, Ramsden DA, Litchfield DW, Lees-Miller SP, Weinfeld M.
    J Biol Chem; 2010 Nov 26; 285(48):37619-29. PubMed ID: 20852255
    [Abstract] [Full Text] [Related]

  • 19. Persistent 3'-phosphate termini and increased cytotoxicity of radiomimetic DNA double-strand breaks in cells lacking polynucleotide kinase/phosphatase despite presence of an alternative 3'-phosphatase.
    Chalasani SL, Kawale AS, Akopiants K, Yu Y, Fanta M, Weinfeld M, Povirk LF.
    DNA Repair (Amst); 2018 Aug 26; 68():12-24. PubMed ID: 29807321
    [Abstract] [Full Text] [Related]

  • 20. Discovery of potential inhibitors targeting the kinase domain of polynucleotide kinase/phosphatase (PNKP): Homology modeling, virtual screening based on multiple conformations, and molecular dynamics simulation.
    Zhu J, Zhang H, Jia L, Ma L, Xu L, Chen Y, Cai Y, Li H, Huang G, Jin J.
    Comput Biol Chem; 2021 Oct 26; 94():107517. PubMed ID: 34456161
    [Abstract] [Full Text] [Related]

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