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Journal Abstract Search

233 related items for PubMed ID: 3768024

  • 1. Methotrexate analogues-27. Dual inhibition of dihydrofolate reductase and folylpolyglutamate synthetase by methotrexate and aminopterin analogues with a gamma-phosphonate group in the side chain.
    Rosowsky A, Moran RC, Forsch RA, Radike-Smith M, Colman PD, Wick MM, Freisheim JH.
    Biochem Pharmacol; 1986 Oct 01; 35(19):3327-33. PubMed ID: 3768024
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  • 2. Methotrexate analogues. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acids.
    Rosowsky A, Bader H, Kohler W, Freisheim JH, Moran RG.
    J Med Chem; 1988 Jul 01; 31(7):1338-44. PubMed ID: 2898531
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  • 3. Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
    Rosowsky A, Freisheim JH, Moran RG, Solan VC, Bader H, Wright JE, Radike-Smith M.
    J Med Chem; 1986 May 01; 29(5):655-60. PubMed ID: 2871191
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  • 4. Methotrexate analogues. 31. Meta and ortho isomers of aminopterin, compounds with a double bond in the side chain, and a novel analogue modified at the alpha-carbon: chemical and in vitro biological studies.
    Rosowsky A, Bader H, Forsch RA, Moran RG, Freisheim JH.
    J Med Chem; 1988 Apr 01; 31(4):763-8. PubMed ID: 3351853
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  • 5. Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activity.
    Rosowsky A, Bader H, Cucchi CA, Moran RG, Kohler W, Freisheim JH.
    J Med Chem; 1988 Jul 01; 31(7):1332-7. PubMed ID: 3385730
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  • 6. Methotrexate analogues. 28. Synthesis and biological evaluation of new gamma-monoamides of aminopterin and methotrexate.
    Rosowsky A, Bader H, Radike-Smith M, Cucchi CA, Wick MM, Freisheim JH.
    J Med Chem; 1986 Sep 01; 29(9):1703-9. PubMed ID: 3462394
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  • 7. Methotrexate analogues. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphonate: effect on enzyme binding and cell-growth inhibition.
    Rosowsky A, Forsch RA, Moran RG, Kohler W, Freisheim JH.
    J Med Chem; 1988 Jul 01; 31(7):1326-31. PubMed ID: 3385729
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  • 9. Analogues of methotrexate and aminopterin with gamma-methylene and gamma-cyano substitution of the glutamate side chain: synthesis and in vitro biological activity.
    Rosowsky A, Bader H, Freisheim JH.
    J Med Chem; 1991 Jan 01; 34(1):203-8. PubMed ID: 1992118
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  • 10. Biochemical and growth inhibition studies of methotrexate and aminopterin analogues containing a tetrazole ring in place of the gamma-carboxyl group.
    McGuire JJ, Russell CA, Bolanowska WE, Freitag CM, Jones CS, Kalman TI.
    Cancer Res; 1990 Mar 15; 50(6):1726-31. PubMed ID: 2306727
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  • 11. Methotrexate analogues. 25. Chemical and biological studies on the gamma-tert-butyl esters of methotrexate and aminopterin.
    Rosowsky A, Freisheim JH, Bader H, Forsch RA, Susten SS, Cucchi CA, Frei E.
    J Med Chem; 1985 May 15; 28(5):660-7. PubMed ID: 3872941
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  • 14. Inhibition of human liver folylpolyglutamate synthetase by non-gamma-glutamylatable antifolate analogs.
    Clarke L, Rosowsky A, Waxman DJ.
    Mol Pharmacol; 1987 Jan 15; 31(1):122-7. PubMed ID: 3807889
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  • 16. Methotrexate analogues--XVII. Antitumor activity of 4-amino-4-deoxy-N10-methylpteroyl-D,L-homocysteic acid and its dual inhibition of dihydrofolate reductase and folyl polyglutamate synthetase.
    Rosowsky A, Moran RG, Forsch R, Colman P, Uren J, Wick M.
    Biochem Pharmacol; 1984 Jan 01; 33(1):155-61. PubMed ID: 6546690
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  • 18. Synthesis and biological activity of the 2-desamino and 2-desamino-2-methyl analogues of aminopterin and methotrexate.
    Rosowsky A, Forsch RA, Moran RG, Freisheim JH.
    J Med Chem; 1991 Jan 01; 34(1):227-34. PubMed ID: 1992122
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