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2. Activation with plasmin of tow-chain urokinase-type plasminogen activator derived from single-chain urokinase-type plasminogen activator by treatment with thrombin. Lijnen HR, Van Hoef B, Collen D. Eur J Biochem; 1987 Dec 01; 169(2):359-64. PubMed ID: 2961562 [Abstract] [Full Text] [Related]
3. Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator. Nelles L, Lijnen HR, Collen D, Holmes WE. J Biol Chem; 1987 Aug 05; 262(22):10855-62. PubMed ID: 2956260 [Abstract] [Full Text] [Related]
4. Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis. Fleury V, Lijnen HR, Anglés-Cano E. J Biol Chem; 1993 Sep 05; 268(25):18554-9. PubMed ID: 8103046 [Abstract] [Full Text] [Related]
5. Characterization of recombinant human single chain urokinase-type plasminogen activator mutants produced by site-specific mutagenesis of lysine 158. Nelles L, Lijnen HR, Collen D, Holmes WE. J Biol Chem; 1987 Apr 25; 262(12):5682-9. PubMed ID: 3106341 [Abstract] [Full Text] [Related]
6. Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu). Lijnen HR, Van Hoef B, Nelles L, Collen D. J Biol Chem; 1990 Mar 25; 265(9):5232-6. PubMed ID: 1969415 [Abstract] [Full Text] [Related]
7. Characterization of a recombinant fusion protein of the finger domain of tissue-type plasminogen activator with a truncated single chain urokinase-type plasminogen activator. Gheysen D, Lijnen HR, Piérard L, de Foresta F, Demarsin E, Jacobs P, De Wilde M, Bollen A, Collen D. J Biol Chem; 1987 Aug 25; 262(24):11779-84. PubMed ID: 3114253 [Abstract] [Full Text] [Related]
8. Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160. Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D. Eur J Biochem; 1988 Nov 15; 177(3):575-82. PubMed ID: 2973984 [Abstract] [Full Text] [Related]
9. Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells. Barnathan ES, Kuo A, Rosenfeld L, Karikó K, Leski M, Robbiati F, Nolli ML, Henkin J, Cines DB. J Biol Chem; 1990 Feb 15; 265(5):2865-72. PubMed ID: 2154462 [Abstract] [Full Text] [Related]
10. Characterization of a chimeric plasminogen activator consisting of amino acids 1 to 274 of tissue-type plasminogen activator and amino acids 138 to 411 of single-chain urokinase-type plasminogen activator. Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D. J Biol Chem; 1988 Dec 15; 263(35):19083-91. PubMed ID: 3143723 [Abstract] [Full Text] [Related]
11. Nerve growth factor-gamma activates soluble and receptor-bound single chain urokinase-type plasminogen activator. Wolf BB, Vasudevan J, Henkin J, Gonias SL. J Biol Chem; 1993 Aug 05; 268(22):16327-31. PubMed ID: 8393859 [Abstract] [Full Text] [Related]
12. Characterization of domain deletion and/or duplication mutants of a recombinant chimera of tissue-type plasminogen activator and urokinase-type plasminogen activator (rt-PA/u-PA). Nelles L, Lijnen HR, Van Nuffelen A, Demarsin E, Collen D. Thromb Haemost; 1990 Aug 13; 64(1):53-60. PubMed ID: 2148847 [Abstract] [Full Text] [Related]
13. Characterization of plasminogen activation by glycosylphosphatidylinositol-anchored urokinase. Lee SW, Ellis V, Dichek DA. J Biol Chem; 1994 Jan 28; 269(4):2411-8. PubMed ID: 8300567 [Abstract] [Full Text] [Related]
14. Kinetics of plasmin activation of single chain urinary-type plasminogen activator (scu-PA) and demonstration of a high affinity interaction between scu-PA and plasminogen. Longstaff C, Clough AM, Gaffney PJ. J Biol Chem; 1992 Jan 05; 267(1):173-9. PubMed ID: 1730585 [Abstract] [Full Text] [Related]
15. The differential glycosylation of human pro-urokinase from various recombinant mammalian cell lines does not affect activity and binding to PAI-1. Sarubbi E, Nolli ML, Robbiati F, Soffientini A, Parenti F, Cassani G. Thromb Haemost; 1989 Nov 24; 62(3):927-33. PubMed ID: 2512681 [Abstract] [Full Text] [Related]
16. Characterization of a chimaeric plasminogen activator obtained by insertion of the second kringle structure of tissue-type plasminogen activator (amino acids 173 through 262) between residues Asp130 and Ser139 of urokinase-type plasminogen activator. Lijnen HR, Piérard L, Reff ME, Gheysen D. Thromb Res; 1988 Dec 01; 52(5):431-41. PubMed ID: 3146822 [Abstract] [Full Text] [Related]
17. Transformation-dependent activation of urokinase-type plasminogen activator by a plasmin-independent mechanism: involvement of cell surface membranes. Berkenpas MB, Quigley JP. Proc Natl Acad Sci U S A; 1991 Sep 01; 88(17):7768-72. PubMed ID: 1652763 [Abstract] [Full Text] [Related]
18. Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator. Stump DC, Lijnen HR, Collen D. J Biol Chem; 1986 Dec 25; 261(36):17120-6. PubMed ID: 3097021 [Abstract] [Full Text] [Related]
19. Characterization of a recombinant chimeric plasminogen activator with enhanced fibrin binding. Jiao J, Yu M, Ru B. Biochim Biophys Acta; 2001 Apr 07; 1546(2):399-405. PubMed ID: 11295444 [Abstract] [Full Text] [Related]
20. Proteolytic cleavage of urokinase-type plasminogen activator by stromelysin-1 (MMP-3). Ugwu F, Van Hoef B, Bini A, Collen D, Lijnen HR. Biochemistry; 1998 May 19; 37(20):7231-6. PubMed ID: 9585535 [Abstract] [Full Text] [Related] Page: [Next] [New Search]