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Journal Abstract Search


197 related items for PubMed ID: 37797621

  • 1. Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
    Wang M, Li W, Tomimatsu N, Yu CH, Ji JH, Alejo S, Witus SR, Alimbetov D, Fitzgerald O, Wu B, Wang Q, Huang Y, Gan Y, Dong F, Kwon Y, Sareddy GR, Curiel TJ, Habib AA, Hromas R, Dos Santos Passos C, Yao T, Ivanov DN, Brzovic PS, Burma S, Klevit RE, Zhao W.
    Mol Cell; 2023 Oct 19; 83(20):3679-3691.e8. PubMed ID: 37797621
    [Abstract] [Full Text] [Related]

  • 2. The BRCA1/BARD1 ubiquitin ligase and its substrates.
    Witus SR, Stewart MD, Klevit RE.
    Biochem J; 2021 Sep 30; 478(18):3467-3483. PubMed ID: 34591954
    [Abstract] [Full Text] [Related]

  • 3. Protocol for evaluating the E3 ligase activity of BRCA1-BARD1 and its variants by nucleosomal histone ubiquitylation.
    Fitzgerald O, Wu B, Wang M, Maqbool R, Li W, Zhao W.
    STAR Protoc; 2024 Sep 20; 5(3):103294. PubMed ID: 39243377
    [Abstract] [Full Text] [Related]

  • 4. Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
    Hu Q, Botuyan MV, Zhao D, Cui G, Mer E, Mer G.
    Nature; 2021 Aug 20; 596(7872):438-443. PubMed ID: 34321665
    [Abstract] [Full Text] [Related]

  • 5. Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line.
    Li Q, Kaur A, Okada K, McKenney RJ, Engebrecht J.
    PLoS Genet; 2023 Jan 20; 19(1):e1010457. PubMed ID: 36716349
    [Abstract] [Full Text] [Related]

  • 6. BRCA1/BARD1 E3 ubiquitin ligase can modify histones H2A and H2B in the nucleosome particle.
    Thakar A, Parvin J, Zlatanova J.
    J Biomol Struct Dyn; 2010 Feb 20; 27(4):399-406. PubMed ID: 19916563
    [Abstract] [Full Text] [Related]

  • 7. Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.
    Densham RM, Garvin AJ, Stone HR, Strachan J, Baldock RA, Daza-Martin M, Fletcher A, Blair-Reid S, Beesley J, Johal B, Pearl LH, Neely R, Keep NH, Watts FZ, Morris JR.
    Nat Struct Mol Biol; 2016 Jul 20; 23(7):647-55. PubMed ID: 27239795
    [Abstract] [Full Text] [Related]

  • 8. BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes.
    Stewart MD, Zelin E, Dhall A, Walsh T, Upadhyay E, Corn JE, Chatterjee C, King MC, Klevit RE.
    Proc Natl Acad Sci U S A; 2018 Feb 06; 115(6):1316-1321. PubMed ID: 29367421
    [Abstract] [Full Text] [Related]

  • 9. BRCA1 is a histone-H2A-specific ubiquitin ligase.
    Kalb R, Mallery DL, Larkin C, Huang JT, Hiom K.
    Cell Rep; 2014 Aug 21; 8(4):999-1005. PubMed ID: 25131202
    [Abstract] [Full Text] [Related]

  • 10. BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.
    Witus SR, Tuttle LM, Li W, Zelter A, Wang M, Kermoade KE, Wilburn DB, Davis TN, Brzovic PS, Zhao W, Klevit RE.
    EMBO J; 2023 Aug 01; 42(15):e113565. PubMed ID: 37305927
    [Abstract] [Full Text] [Related]

  • 11. The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate.
    Kim BJ, Chan DW, Jung SY, Chen Y, Qin J, Wang Y.
    Cell Rep; 2017 May 30; 19(9):1758-1766. PubMed ID: 28564596
    [Abstract] [Full Text] [Related]

  • 12. mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response.
    Fonseca D, Baquero J, Murphy MR, Aruggoda G, Varriano S, Sapienza C, Mashadova O, Rahman S, Kleiman FE.
    Mol Cell Biol; 2018 Feb 15; 38(4):. PubMed ID: 29180510
    [Abstract] [Full Text] [Related]

  • 13. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains.
    Mallery DL, Vandenberg CJ, Hiom K.
    EMBO J; 2002 Dec 16; 21(24):6755-62. PubMed ID: 12485996
    [Abstract] [Full Text] [Related]

  • 14. Functional analysis of BARD1 missense variants in homology-directed repair and damage sensitivity.
    Adamovich AI, Banerjee T, Wingo M, Duncan K, Ning J, Martins Rodrigues F, Huang KL, Lee C, Chen F, Ding L, Parvin JD.
    PLoS Genet; 2019 Mar 16; 15(3):e1008049. PubMed ID: 30925164
    [Abstract] [Full Text] [Related]

  • 15. CRL4-DCAF8L2 E3 ligase promotes ubiquitination and degradation of BARD1.
    Deng J, Zhang T, Liu F, Han Q, Li Q, Guo X, Ma Y, Li L, Shao G.
    Biochem Biophys Res Commun; 2022 Jun 30; 611():107-113. PubMed ID: 35487060
    [Abstract] [Full Text] [Related]

  • 16. The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection.
    Billing D, Horiguchi M, Wu-Baer F, Taglialatela A, Leuzzi G, Nanez SA, Jiang W, Zha S, Szabolcs M, Lin CS, Ciccia A, Baer R.
    Mol Cell; 2018 Oct 04; 72(1):127-139.e8. PubMed ID: 30244837
    [Abstract] [Full Text] [Related]

  • 17. Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.
    Stewart MD, Duncan ED, Coronado E, DaRosa PA, Pruneda JN, Brzovic PS, Klevit RE.
    Protein Sci; 2017 Mar 04; 26(3):475-483. PubMed ID: 27977889
    [Abstract] [Full Text] [Related]

  • 18. Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.
    Dizin E, Irminger-Finger I.
    Int J Biochem Cell Biol; 2010 May 04; 42(5):693-700. PubMed ID: 20060929
    [Abstract] [Full Text] [Related]

  • 19. BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.
    Becker JR, Clifford G, Bonnet C, Groth A, Wilson MD, Chapman JR.
    Nature; 2021 Aug 04; 596(7872):433-437. PubMed ID: 34321663
    [Abstract] [Full Text] [Related]

  • 20. BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
    Witus SR, Burrell AL, Farrell DP, Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM, Stewart MD, Brzovic PS, Chatterjee C, Zhao W, DiMaio F, Kollman JM, Klevit RE.
    Nat Struct Mol Biol; 2021 Mar 04; 28(3):268-277. PubMed ID: 33589814
    [Abstract] [Full Text] [Related]


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