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Journal Abstract Search

194 related items for PubMed ID: 37921907

  • 1. Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug-Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil.
    Iga K, Kiriyama A.
    Clin Pharmacokinet; 2024 Jan; 63(1):43-56. PubMed ID: 37921907
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  • 2. Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide.
    Varma MV, Lin J, Bi YA, Kimoto E, Rodrigues AD.
    Drug Metab Dispos; 2015 Jul; 43(7):1108-18. PubMed ID: 25941268
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  • 3. Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data.
    Kim SJ, Toshimoto K, Yao Y, Yoshikado T, Sugiyama Y.
    J Pharm Sci; 2017 Sep; 106(9):2715-2726. PubMed ID: 28479356
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  • 4. Inhibition of CYP2C8 by Acyl Glucuronides of Gemfibrozil and Clopidogrel: Pharmacological Significance, Progress and Challenges.
    Shah MB.
    Biomolecules; 2022 Sep 01; 12(9):. PubMed ID: 36139056
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  • 5. Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole.
    Türk D, Hanke N, Wolf S, Frechen S, Eissing T, Wendl T, Schwab M, Lehr T.
    Clin Pharmacokinet; 2019 Dec 01; 58(12):1595-1607. PubMed ID: 31129789
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  • 7. A long-standing mystery solved: the formation of 3-hydroxydesloratadine is catalyzed by CYP2C8 but prior glucuronidation of desloratadine by UDP-glucuronosyltransferase 2B10 is an obligatory requirement.
    Kazmi F, Barbara JE, Yerino P, Parkinson A.
    Drug Metab Dispos; 2015 Apr 01; 43(4):523-33. PubMed ID: 25595597
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  • 9. Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance.
    Miners JO, Polasek TM, Hulin JA, Rowland A, Meech R.
    Pharmacol Ther; 2023 Aug 01; 248():108459. PubMed ID: 37263383
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  • 11. Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.
    Backman JT, Filppula AM, Niemi M, Neuvonen PJ.
    Pharmacol Rev; 2016 Jan 01; 68(1):168-241. PubMed ID: 26721703
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  • 13. Clarification of the Mechanism of Clopidogrel-Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information.
    Kim SJ, Yoshikado T, Ieiri I, Maeda K, Kimura M, Irie S, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2016 Oct 01; 44(10):1622-32. PubMed ID: 27457785
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  • 15. Implications of intercorrelation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: a case study with repaglinide.
    Doki K, Darwich AS, Achour B, Tornio A, Backman JT, Rostami-Hodjegan A.
    Br J Clin Pharmacol; 2018 May 01; 84(5):972-986. PubMed ID: 29381228
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  • 16. Quantitative Analysis of Complex Drug-Drug Interactions between Cerivastatin and Metabolism/Transport Inhibitors Using Physiologically Based Pharmacokinetic Modeling.
    Yao Y, Toshimoto K, Kim SJ, Yoshikado T, Sugiyama Y.
    Drug Metab Dispos; 2018 Jul 01; 46(7):924-933. PubMed ID: 29712725
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  • 17. Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes.
    Marzolini C, Rajoli R, Battegay M, Elzi L, Back D, Siccardi M.
    Clin Pharmacokinet; 2017 Apr 01; 56(4):409-420. PubMed ID: 27599706
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