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122 related items for PubMed ID: 37967142

  • 1. Expression of Concern: Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells.
    PLOS ONE Editors.
    PLoS One; 2023; 18(11):e0294622. PubMed ID: 37967142
    [No Abstract] [Full Text] [Related]

  • 2. Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells.
    Ma YC, Wang ZX, Jin SJ, Zhang YX, Hu GQ, Cui DT, Wang JS, Wang M, Wang FQ, Zhao ZJ.
    PLoS One; 2016; 11(10):e0162821. PubMed ID: 27760157
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of epidermal growth factor receptor tyrosine kinase by chalcone derivatives.
    Yang EB, Guo YJ, Zhang K, Chen YZ, Mack P.
    Biochim Biophys Acta; 2001 Dec 17; 1550(2):144-52. PubMed ID: 11755203
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers.
    Li PH, Jiang H, Zhang WJ, Li YL, Zhao MC, Zhou W, Zhang LY, Tang YD, Dong CZ, Huang ZS, Chen HX, Du ZY.
    Eur J Med Chem; 2018 Feb 10; 145():498-510. PubMed ID: 29335211
    [Abstract] [Full Text] [Related]

  • 5. Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).
    Wang X, Chen Z, Tong L, Tan S, Zhou W, Peng T, Han K, Ding J, Xie H, Xu Y.
    Eur J Med Chem; 2013 Jul 10; 65():477-86. PubMed ID: 23770449
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives.
    Na Y, Nam JM.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):211-4. PubMed ID: 21115246
    [Abstract] [Full Text] [Related]

  • 7. Design, Synthesis and Anti-Tumor Activity of Novel Benzimidazole-Chalcone Hybrids as Non-Intercalative Topoisomerase II Catalytic Inhibitors.
    Zhou W, Zhang W, Peng Y, Jiang ZH, Zhang L, Du Z.
    Molecules; 2020 Jul 12; 25(14):. PubMed ID: 32664629
    [Abstract] [Full Text] [Related]

  • 8. Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
    Nam S, Wen W, Schroeder A, Herrmann A, Yu H, Cheng X, Merz KH, Eisenbrand G, Li H, Yuan YC, Jove R.
    Mol Oncol; 2013 Jun 12; 7(3):369-78. PubMed ID: 23206899
    [Abstract] [Full Text] [Related]

  • 9. Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Alaaeldin R, Abdel-Rahman IM, Ali FEM, Bekhit AA, Elhamadany EY, Zhao QL, Cui ZG, Fathy M.
    Molecules; 2022 Nov 17; 27(22):. PubMed ID: 36432094
    [Abstract] [Full Text] [Related]

  • 10. Effects of protein tyrosine kinase inhibitors with different modes of action on topoisomerase activity and death of IL-2-dependent CTLL-2 cells.
    Azuma Y, Onishi Y, Sato Y, Kizaki H.
    J Biochem; 1995 Aug 17; 118(2):312-8. PubMed ID: 8543564
    [Abstract] [Full Text] [Related]

  • 11. Mechanism of topoisomerase II inhibition by staurosporine and other protein kinase inhibitors.
    Lassota P, Singh G, Kramer R.
    J Biol Chem; 1996 Oct 18; 271(42):26418-23. PubMed ID: 8824299
    [Abstract] [Full Text] [Related]

  • 12. Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II.
    Bridewell DJ, Finlay GJ, Baguley BC.
    Cancer Chemother Pharmacol; 1999 Oct 18; 43(4):302-8. PubMed ID: 10071981
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors.
    Huo PC, Hu Q, Shu S, Zhou QH, He RJ, Hou J, Guan XQ, Tu DZ, Hou XD, Liu P, Zhang N, Liu ZG, Ge GB.
    Bioorg Med Chem; 2021 Jan 01; 29():115853. PubMed ID: 33214035
    [Abstract] [Full Text] [Related]

  • 14. FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells.
    Liu W, Bloom DA, Cance WG, Kurenova EV, Golubovskaya VM, Hochwald SN.
    Carcinogenesis; 2008 Jun 01; 29(6):1096-107. PubMed ID: 18263593
    [Abstract] [Full Text] [Related]

  • 15. Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.
    Oppegard LM, Ougolkov AV, Luchini DN, Schoon RA, Goodell JR, Kaur H, Billadeau DD, Ferguson DM, Hiasa H.
    Eur J Pharmacol; 2009 Jan 14; 602(2-3):223-9. PubMed ID: 19071108
    [Abstract] [Full Text] [Related]

  • 16. Carbazole derivatives containing chalcone analogues targeting topoisomerase II inhibition: First principles characterization and QSAR modelling.
    Ghamri M, Harkati D, Belaidi S, Boudergua S, Said RB, Linguerri R, Chambaud G, Hochlaf M.
    Spectrochim Acta A Mol Biomol Spectrosc; 2020 Dec 05; 242():118724. PubMed ID: 32769058
    [Abstract] [Full Text] [Related]

  • 17. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S, Vandenberghe I, Robin M, Annereau JP, Créancier L, Pique V, Galy JP, Kruczynski A, Barret JM, Bailly C.
    Biochem Pharmacol; 2007 Jun 15; 73(12):1863-72. PubMed ID: 17391647
    [Abstract] [Full Text] [Related]

  • 18. A novel chalcone derivative exerts anticancer effects by promoting apoptotic cell death of human pancreatic cancer cells.
    Baek S, Nah S, Park JY, Lee SJ, Kang YG, Kwon SH, Oh SJ, Lee KP, Moon BS.
    Bioorg Med Chem; 2023 Oct 01; 93():117458. PubMed ID: 37634418
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis, and evaluation of novel N-1 fluoroquinolone derivatives: Probing for binding contact with the active site tyrosine of gyrase.
    Towle TR, Kulkarni CA, Oppegard LM, Williams BP, Picha TA, Hiasa H, Kerns RJ.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1903-1910. PubMed ID: 29661533
    [Abstract] [Full Text] [Related]

  • 20. Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.
    Abdel-Aziz M, Park SE, Abuo-Rahma Gel-D, Sayed MA, Kwon Y.
    Eur J Med Chem; 2013 Nov 01; 69():427-38. PubMed ID: 24090914
    [Abstract] [Full Text] [Related]

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