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540 related items for PubMed ID: 3801051

  • 1. Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.
    Ozols RF, Louie KG, Plowman J, Behrens BC, Fine RL, Dykes D, Hamilton TC.
    Biochem Pharmacol; 1987 Jan 01; 36(1):147-53. PubMed ID: 3801051
    [Abstract] [Full Text] [Related]

  • 2. In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy.
    Siemann DW, Beyers KL.
    Br J Cancer; 1993 Dec 01; 68(6):1071-9. PubMed ID: 8260357
    [Abstract] [Full Text] [Related]

  • 3. Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.
    Green JA, Vistica DT, Young RC, Hamilton TC, Rogan AM, Ozols RF.
    Cancer Res; 1984 Nov 01; 44(11):5427-31. PubMed ID: 6488194
    [Abstract] [Full Text] [Related]

  • 4. Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent buthionine sulfoximine.
    Kramer RA, Greene K, Ahmad S, Vistica DT.
    Cancer Res; 1987 Mar 15; 47(6):1593-7. PubMed ID: 3815359
    [Abstract] [Full Text] [Related]

  • 5. Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice.
    Skapek SX, Colvin OM, Griffith OW, Elion GB, Bigner DD, Friedman HS.
    Cancer Res; 1988 May 15; 48(10):2764-7. PubMed ID: 3359437
    [Abstract] [Full Text] [Related]

  • 6. Cytotoxic effects of glutathione synthesis inhibition by L-buthionine-(SR)-sulfoximine on human and murine tumor cells.
    Dorr RT, Liddil JD, Soble MJ.
    Invest New Drugs; 1986 May 15; 4(4):305-13. PubMed ID: 3583642
    [Abstract] [Full Text] [Related]

  • 7. In vivo modulation of glutathione by buthionine sulfoximine: effect on marrow response to melphalan.
    Russo A, Tochner Z, Phillips T, Carmichael J, DeGraff W, Friedman N, Fisher J, Mitchell JB.
    Int J Radiat Oncol Biol Phys; 1986 Jul 15; 12(7):1187-9. PubMed ID: 3744938
    [Abstract] [Full Text] [Related]

  • 8. Effect of buthionine sulfoximine on PtII and PtIV drug accumulation and the formation of glutathione conjugates in human ovarian-carcinoma cell lines.
    Mistry P, Loh SY, Kelland LR, Harrap KR.
    Int J Cancer; 1993 Nov 11; 55(5):848-56. PubMed ID: 8244583
    [Abstract] [Full Text] [Related]

  • 9. Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.
    O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T, Brennan J, Bookman MA, Hoffman J, Young RC, Comis RL, Ozols RF.
    J Clin Oncol; 1996 Jan 11; 14(1):249-56. PubMed ID: 8558205
    [Abstract] [Full Text] [Related]

  • 10. Effect of glutathione depletion by L-buthionine sulfoximine on the cytotoxicity of cyclophosphamide in single and fractionated doses to EMT6/SF mouse tumors and bone marrow.
    Ono K, Shrieve DC.
    J Natl Cancer Inst; 1987 Oct 11; 79(4):811-5. PubMed ID: 3477662
    [Abstract] [Full Text] [Related]

  • 11. Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells.
    Chen G, Waxman DJ.
    Biochem Pharmacol; 1994 Mar 15; 47(6):1079-87. PubMed ID: 8147907
    [Abstract] [Full Text] [Related]

  • 12. Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion.
    Rosenberg MC, Colvin OM, Griffith OW, Bigner SH, Elion GB, Horton JK, Lilley E, Bigner DD, Friedman HS.
    Cancer Res; 1989 Dec 15; 49(24 Pt 1):6917-22. PubMed ID: 2582434
    [Abstract] [Full Text] [Related]

  • 13. Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion.
    Friedman HS, Colvin OM, Griffith OW, Lippitz B, Elion GB, Schold SC, Hilton J, Bigner DD.
    J Natl Cancer Inst; 1989 Apr 05; 81(7):524-7. PubMed ID: 2921776
    [Abstract] [Full Text] [Related]

  • 14. The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.
    Mistry P, Kelland LR, Abel G, Sidhar S, Harrap KR.
    Br J Cancer; 1991 Aug 05; 64(2):215-20. PubMed ID: 1892748
    [Abstract] [Full Text] [Related]

  • 15. Melphalan-induced toxicity in nude mice following pretreatment with buthionine sulfoximine.
    Skapek SX, VanDellen AF, McMahon DP, Postels DG, Griffith OW, Bigner DD, Friedman HS.
    Cancer Chemother Pharmacol; 1991 Aug 05; 28(1):15-21. PubMed ID: 2040029
    [Abstract] [Full Text] [Related]

  • 16. Glutathione depletion increases the cytotoxicity of melphalan to PC-3, an androgen-insensitive prostate cancer cell line.
    Canada A, Herman L, Kidd K, Robertson C, Trump D.
    Cancer Chemother Pharmacol; 1993 Aug 05; 32(1):73-7. PubMed ID: 8462127
    [Abstract] [Full Text] [Related]

  • 17. Mechanisms of cross-resistance between radiation and antineoplastic drugs.
    Ozols RF, Masuda H, Hamilton TC.
    NCI Monogr; 1988 Aug 05; (6):159-65. PubMed ID: 3352759
    [Abstract] [Full Text] [Related]

  • 18. Effects of buthionine sulfoximine treatment on cellular glutathione levels and cytotoxicities of cisplatin, carboplatin and radiation in human stomach and ovarian cancer cell lines.
    Lee KS, Kim HK, Moon HS, Hong YS, Kang JH, Kim DJ, Park JG.
    Korean J Intern Med; 1992 Jul 05; 7(2):111-7. PubMed ID: 1306072
    [Abstract] [Full Text] [Related]

  • 19. Pharmacokinetics of buthionine sulfoximine (NSC 326231) and its effect on melphalan-induced toxicity in mice.
    Smith AC, Liao JT, Page JG, Wientjes MG, Grieshaber CK.
    Cancer Res; 1989 Oct 01; 49(19):5385-91. PubMed ID: 2766304
    [Abstract] [Full Text] [Related]

  • 20. Potentiation of the cytostatic effect of melphalan on colorectal cancer hepatic metastases by infusion of buthionine sulfoximine (BSO) in the rat: enhanced tumor glutathione depletion by infusion of BSO in the hepatic artery.
    Vahrmeijer AL, van Dierendonck JH, Schutrups J, van de Velde CJ, Mulder GJ.
    Cancer Chemother Pharmacol; 1999 Oct 01; 44(2):111-6. PubMed ID: 10412944
    [Abstract] [Full Text] [Related]

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