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155 related items for PubMed ID: 3802414

  • 1. Effects of alpha-deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
    Hecht SS, Lin D, Castonguay A, Rivenson A.
    Carcinogenesis; 1987 Feb; 8(2):291-4. PubMed ID: 3802414
    [Abstract] [Full Text] [Related]

  • 2. Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
    Morse MA, Wang CX, Amin SG, Hecht SS, Chung FL.
    Carcinogenesis; 1988 Oct; 9(10):1891-5. PubMed ID: 3168166
    [Abstract] [Full Text] [Related]

  • 3. Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
    Hecht SS, Trushin N, Castonguay A, Rivenson A.
    Cancer Res; 1986 Feb; 46(2):498-502. PubMed ID: 3940627
    [Abstract] [Full Text] [Related]

  • 4. Evidence supporting the role of DNA pyridyloxobutylation in rat nasal carcinogenesis by tobacco-specific nitrosamines.
    Trushin N, Rivenson A, Hecht SS.
    Cancer Res; 1994 Mar 01; 54(5):1205-11. PubMed ID: 8118807
    [Abstract] [Full Text] [Related]

  • 5. Effects of alpha-deuterium substitution on the mutagenicity of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Hecht SS, Lin D, Castonguay A.
    Carcinogenesis; 1983 Mar 01; 4(3):305-10. PubMed ID: 6339096
    [Abstract] [Full Text] [Related]

  • 6. Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice.
    Hecht SS, Jordan KG, Choi CI, Trushin N.
    Carcinogenesis; 1990 Jun 01; 11(6):1017-20. PubMed ID: 2347060
    [Abstract] [Full Text] [Related]

  • 7. Comparative carcinogenicity in F344 rats of the tobacco-specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
    Hecht SS, Chen CB, Ohmori T, Hoffmann D.
    Cancer Res; 1980 Feb 01; 40(2):298-302. PubMed ID: 7356512
    [Abstract] [Full Text] [Related]

  • 8. Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines.
    Rivenson A, Hoffmann D, Prokopczyk B, Amin S, Hecht SS.
    Cancer Res; 1988 Dec 01; 48(23):6912-7. PubMed ID: 3180100
    [Abstract] [Full Text] [Related]

  • 9. Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Belinsky SA, Foley JF, White CM, Anderson MW, Maronpot RR.
    Cancer Res; 1990 Jun 15; 50(12):3772-80. PubMed ID: 2340522
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate.
    Morse MA, Wang CX, Stoner GD, Mandal S, Conran PB, Amin SG, Hecht SS, Chung FL.
    Cancer Res; 1989 Feb 01; 49(3):549-53. PubMed ID: 2910476
    [Abstract] [Full Text] [Related]

  • 11. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
    Liu LL, Alaoui-Jamali MA, el Alami N, Castonguay A.
    Cancer Res; 1990 Mar 15; 50(6):1810-6. PubMed ID: 2306734
    [Abstract] [Full Text] [Related]

  • 12. Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine in Syrian golden hamsters.
    Hoffmann D, Castonguay A, Rivenson A, Hecht SS.
    Cancer Res; 1981 Jun 15; 41(6):2386-93. PubMed ID: 7237437
    [Abstract] [Full Text] [Related]

  • 13. A study of tobacco carcinogenesis: effect of the fat content of the diet on the carcinogenic activity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
    Hoffmann D, Rivenson A, Abbi R, Wynder EL.
    Cancer Res; 1993 Jun 15; 53(12):2758-61. PubMed ID: 8389244
    [Abstract] [Full Text] [Related]

  • 14. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR, McIntee EJ, Kenney PM, Upadhyaya P, Peterson LA, Hecht SS.
    Chem Res Toxicol; 2003 Jun 15; 16(6):794-806. PubMed ID: 12807363
    [Abstract] [Full Text] [Related]

  • 15. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug 15; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

  • 16. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME, Foiles PG, Miglietta LM, Hecht SS.
    Cancer Res; 1997 Jan 15; 57(2):259-66. PubMed ID: 9000565
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schrader E, Hirsch-Ernst KI, Richter E, Foth H.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar 15; 357(3):336-43. PubMed ID: 9550307
    [Abstract] [Full Text] [Related]

  • 18. DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Hecht SS, Trushin N.
    Carcinogenesis; 1988 Sep 15; 9(9):1665-8. PubMed ID: 3409470
    [Abstract] [Full Text] [Related]

  • 19. Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
    Murphy SE, Nunes MG, Hatala MA.
    Chem Biol Interact; 1997 Mar 14; 103(3):153-66. PubMed ID: 9134006
    [Abstract] [Full Text] [Related]

  • 20. Dose-response study of the carcinogenicity of tobacco-specific N-nitrosamines in F344 rats.
    Hoffmann D, Rivenson A, Amin S, Hecht SS.
    J Cancer Res Clin Oncol; 1984 Mar 14; 108(1):81-6. PubMed ID: 6746721
    [Abstract] [Full Text] [Related]

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