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436 related items for PubMed ID: 3815742

  • 1. Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adducts.
    Lai CC, Miller EC, Miller JA, Liem A.
    Carcinogenesis; 1987 Mar; 8(3):471-8. PubMed ID: 3815742
    [Abstract] [Full Text] [Related]

  • 2. N-sulfoöxy-2-aminofluorene is the major ultimate electrophilic and carcinogenic metabolite of N-hydroxy-2-acetylaminofluorene in the livers of infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice.
    Lai CC, Miller JA, Miller EC, Liem A.
    Carcinogenesis; 1985 Jul; 6(7):1037-45. PubMed ID: 3860305
    [Abstract] [Full Text] [Related]

  • 3. The essential role of microsomal deacetylase activity in the metabolic activation, DNA-(deoxyguanosin-8-yl)-2-aminofluorene adduct formation and initiation of liver tumors by N-hydroxy-2-acetylaminofluorene in the livers of infant male B6C3F1 mice.
    Lai CC, Miller EC, Miller JA, Liem A.
    Carcinogenesis; 1988 Jul; 9(7):1295-302. PubMed ID: 3383346
    [Abstract] [Full Text] [Related]

  • 4. Sulfuric acid esters as major ultimate electrophilic and hepatocarcinogenic metabolites of 4-aminoazobenzene and its N-methyl derivatives in infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice.
    Delclos KB, Miller EC, Miller JA, Liem A.
    Carcinogenesis; 1986 Feb; 7(2):277-87. PubMed ID: 2419005
    [Abstract] [Full Text] [Related]

  • 5. Role of sulfation in the formation of DNA adducts from N-hydroxy-2-acetylaminofluorene in rat liver in vivo. Inhibition of N-acetylated aminofluorene adduct formation by pentachlorophenol.
    Meerman JH, Beland FA, Mulder GJ.
    Carcinogenesis; 1981 Feb; 2(5):413-6. PubMed ID: 7273322
    [Abstract] [Full Text] [Related]

  • 6. 4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice.
    Delclos KB, Tarpley WG, Miller EC, Miller JA.
    Cancer Res; 1984 Jun; 44(6):2540-50. PubMed ID: 6426782
    [Abstract] [Full Text] [Related]

  • 7. The role of specific DNA adducts in the induction of micronuclei by N-hydroxy-2-acetylaminofluorene in rat liver in vivo.
    van de Poll ML, van der Hulst DA, Tates AD, Mulder GJ, Meerman JH.
    Carcinogenesis; 1989 Apr; 10(4):717-22. PubMed ID: 2702720
    [Abstract] [Full Text] [Related]

  • 8. Major role of hepatic sulfotransferase activity in the metabolic activation, DNA adduct formation, and carcinogenicity of 1'-hydroxy-2',3'-dehydroestragole in infant male C57BL/6J x C3H/HeJ F1 mice.
    Fennell TR, Wiseman RW, Miller JA, Miller EC.
    Cancer Res; 1985 Nov; 45(11 Pt 1):5310-20. PubMed ID: 3863702
    [Abstract] [Full Text] [Related]

  • 9. Aminofluorene-DNA adduct formation in Salmonella typhimurium exposed to the carcinogen N-hydroxy-2-acetylaminofluorene.
    Beranek DT, White GL, Heflich RH, Beland FA.
    Proc Natl Acad Sci U S A; 1982 Sep; 79(17):5175-8. PubMed ID: 6752940
    [Abstract] [Full Text] [Related]

  • 10. Quantification of adducts formed in DNA treated with N-acetoxy-2-acetylaminofluorene or N-hydroxy-2-aminofluorene: comparison of trifluoroacetic acid and enzymatic degradation.
    Tang M, Lieberman MW.
    Carcinogenesis; 1983 Aug; 4(8):1001-6. PubMed ID: 6307542
    [Abstract] [Full Text] [Related]

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  • 12. The binding of N-hydroxy-2-acetylaminofluorene to DNA and repair of the adducts in primary rat hepatocyte cultures.
    Howard PC, Casciano DA, Beland FA, Shaddock JG.
    Carcinogenesis; 1981 Aug; 2(2):97-102. PubMed ID: 6168407
    [Abstract] [Full Text] [Related]

  • 13. The 32P-post-labeling method in quantitative DNA adduct dosimetry of 2-acetylaminofluorene-induced mutagenicity in Chinese hamster ovary cells and Salmonella typhimurium TA1538.
    Arce GT, Cline DT, Mead JE.
    Carcinogenesis; 1987 Apr; 8(4):515-20. PubMed ID: 3549038
    [Abstract] [Full Text] [Related]

  • 14. Persistence of DNA adducts in rat liver and kidney after multiple doses of the carcinogen N-hydroxy-2-acetylaminofluorene.
    Beland FA, Dooley KL, Jackson CD.
    Cancer Res; 1982 Apr; 42(4):1348-54. PubMed ID: 6949639
    [Abstract] [Full Text] [Related]

  • 15. The genotoxicity of aromatic amines in primary hepatocytes isolated from C57BL/6 and DBA/2 mice.
    Møller ME, Glowinski IB, Thorgeirsson SS.
    Carcinogenesis; 1984 Jun; 5(6):797-804. PubMed ID: 6722987
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of 2-acetylaminofluorene in the Chinese hamster ovary cell mutation assay.
    Heflich RH, Djurić Z, Zhuo Z, Fullerton NF, Casciano DA, Beland FA.
    Environ Mol Mutagen; 1988 Jun; 11(2):167-81. PubMed ID: 3345736
    [Abstract] [Full Text] [Related]

  • 17. Formation of DNA adducts from N-acetoxy-2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene in rat hemopoietic tissues in vivo.
    Vu VT, Grantham PH, Roller PP, Hankins WD, Wirth PJ, Thorgeirsson SS.
    Cancer Res; 1986 Jan; 46(1):233-8. PubMed ID: 3940194
    [Abstract] [Full Text] [Related]

  • 18. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
    Boberg EW, Miller EC, Miller JA, Poland A, Liem A.
    Cancer Res; 1983 Nov; 43(11):5163-73. PubMed ID: 6577945
    [Abstract] [Full Text] [Related]

  • 19. Formation and persistence of DNA adducts from the carcinogen N-hydroxy-2-acetylaminofluorene in rat mammary gland in vivo.
    Allaben WT, Weis CC, Fullerton NF, Beland FA.
    Carcinogenesis; 1983 Aug; 4(8):1067-70. PubMed ID: 6872152
    [Abstract] [Full Text] [Related]

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