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Journal Abstract Search


190 related items for PubMed ID: 38440860

  • 1. Evidence that Xrn1 is in complex with Gcn1, and is required for full levels of eIF2α phosphorylation.
    Shanmugam R, Anderson R, Schiemann AH, Sattlegger E.
    Biochem J; 2024 Apr 10; 481(7):481-498. PubMed ID: 38440860
    [Abstract] [Full Text] [Related]

  • 2. Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation.
    Visweswaraiah J, Lee SJ, Hinnebusch AG, Sattlegger E.
    J Biol Chem; 2012 Nov 02; 287(45):37757-68. PubMed ID: 22888004
    [Abstract] [Full Text] [Related]

  • 3. A genetic approach to identify amino acids in Gcn1 required for Gcn2 activation.
    Gottfried S, Koloamatangi SMBMJ, Daube C, Schiemann AH, Sattlegger E.
    PLoS One; 2022 Nov 02; 17(11):e0277648. PubMed ID: 36441697
    [Abstract] [Full Text] [Related]

  • 4. YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.
    Sattlegger E, Swanson MJ, Ashcraft EA, Jennings JL, Fekete RA, Link AJ, Hinnebusch AG.
    J Biol Chem; 2004 Jul 16; 279(29):29952-62. PubMed ID: 15126500
    [Abstract] [Full Text] [Related]

  • 5. Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2.
    Lee SJ, Swanson MJ, Sattlegger E.
    Biochem J; 2015 Mar 15; 466(3):547-59. PubMed ID: 25437641
    [Abstract] [Full Text] [Related]

  • 6. Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.
    Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG.
    Mol Cell Biol; 1997 Aug 15; 17(8):4474-89. PubMed ID: 9234705
    [Abstract] [Full Text] [Related]

  • 7. Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2.
    Kubota H, Ota K, Sakaki Y, Ito T.
    J Biol Chem; 2001 May 18; 276(20):17591-6. PubMed ID: 11350982
    [Abstract] [Full Text] [Related]

  • 8. The Gcn2-eIF2α pathway connects iron and amino acid homeostasis in Saccharomyces cerevisiae.
    Caballero-Molada M, Planes MD, Benlloch H, Atares S, Naranjo MA, Serrano R.
    Biochem J; 2018 Apr 30; 475(8):1523-1534. PubMed ID: 29626156
    [Abstract] [Full Text] [Related]

  • 9. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.
    Marton MJ, Crouch D, Hinnebusch AG.
    Mol Cell Biol; 1993 Jun 30; 13(6):3541-56. PubMed ID: 8497269
    [Abstract] [Full Text] [Related]

  • 10. Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity.
    Visweswaraiah J, Lageix S, Castilho BA, Izotova L, Kinzy TG, Hinnebusch AG, Sattlegger E.
    J Biol Chem; 2011 Oct 21; 286(42):36568-79. PubMed ID: 21849502
    [Abstract] [Full Text] [Related]

  • 11.
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  • 12. Asp56 in actin is critical for the full activity of the amino acid starvation-responsive kinase Gcn2.
    Ramesh R, Dautel M, Lee Y, Kim Y, Storey K, Gottfried S, Goss Kinzy T, Huh WK, Sattlegger E.
    FEBS Lett; 2021 Jul 21; 595(14):1886-1901. PubMed ID: 34096057
    [Abstract] [Full Text] [Related]

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  • 14. Evidence that Yih1 resides in a complex with ribosomes.
    Waller T, Lee SJ, Sattlegger E.
    FEBS J; 2012 May 21; 279(10):1761-76. PubMed ID: 22404850
    [Abstract] [Full Text] [Related]

  • 15. Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation.
    Sattlegger E, Hinnebusch AG.
    J Biol Chem; 2005 Apr 22; 280(16):16514-21. PubMed ID: 15722345
    [Abstract] [Full Text] [Related]

  • 16. Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation.
    Garcia-Barrio M, Dong J, Ufano S, Hinnebusch AG.
    EMBO J; 2000 Apr 17; 19(8):1887-99. PubMed ID: 10775272
    [Abstract] [Full Text] [Related]

  • 17. IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation.
    Pereira CM, Sattlegger E, Jiang HY, Longo BM, Jaqueta CB, Hinnebusch AG, Wek RC, Mello LE, Castilho BA.
    J Biol Chem; 2005 Aug 05; 280(31):28316-23. PubMed ID: 15937339
    [Abstract] [Full Text] [Related]

  • 18. Global phosphoproteomics pinpoints uncharted Gcn2-mediated mechanisms of translational control.
    Dokládal L, Stumpe M, Pillet B, Hu Z, Garcia Osuna GM, Kressler D, Dengjel J, De Virgilio C.
    Mol Cell; 2021 May 06; 81(9):1879-1889.e6. PubMed ID: 33743194
    [Abstract] [Full Text] [Related]

  • 19. Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.
    Sattlegger E, Barbosa JA, Moraes MC, Martins RM, Hinnebusch AG, Castilho BA.
    J Biol Chem; 2011 Mar 25; 286(12):10341-55. PubMed ID: 21239490
    [Abstract] [Full Text] [Related]

  • 20. GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells.
    Vazquez de Aldana CR, Marton MJ, Hinnebusch AG.
    EMBO J; 1995 Jul 03; 14(13):3184-99. PubMed ID: 7621831
    [Abstract] [Full Text] [Related]


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