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108 related items for PubMed ID: 3848491

  • 1. Substituted 2-pyrones, 2-pyridones, and other congeners of elasnin as potential agents for the treatment of chronic obstructive lung diseases.
    Groutas WC, Stanga MA, Brubaker MJ, Huang TL, Moi MK, Carroll RT.
    J Med Chem; 1985 Aug; 28(8):1106-9. PubMed ID: 3848491
    [Abstract] [Full Text] [Related]

  • 2. Specific inhibition of human leukocyte elastase by substituted alpha-pyrones.
    Groutas WC, Abrams WR, Carroll RT, Moi MK, Miller KE, Margolis MT.
    Experientia; 1984 Apr 15; 40(4):361-2. PubMed ID: 6562017
    [Abstract] [Full Text] [Related]

  • 3. Non-peptidic inhibitors of human leukocyte elastase. 1. The design and synthesis of pyridone-containing inhibitors.
    Warner P, Green RC, Gomes B, Strimpler AM.
    J Med Chem; 1994 Sep 16; 37(19):3090-9. PubMed ID: 7932532
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.
    Spencer RW, Copp LJ, Pfister JR.
    J Med Chem; 1985 Dec 16; 28(12):1828-32. PubMed ID: 4068006
    [Abstract] [Full Text] [Related]

  • 5. Nonpeptidic inhibitors of human leukocyte elastase. 2. Design, synthesis, and in vitro activity of a series of 3-amino-6-arylopyridin-2-one trifluoromethyl ketones.
    Damewood JR, Edwards PD, Feeney S, Gomes BC, Steelman GB, Tuthill PA, Williams JC, Warner P, Woolson SA, Wolanin DJ.
    J Med Chem; 1994 Sep 30; 37(20):3303-12. PubMed ID: 7932558
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of human sputum elastase by substituted 2-pyrones.
    Cook L, Ternai B, Ghosh P.
    J Med Chem; 1987 Jun 30; 30(6):1017-23. PubMed ID: 3647139
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of human leukocyte elastase bound to elastin: relative ineffectiveness and two mechanisms of inhibitory activity.
    Morrison HM, Welgus HG, Stockley RA, Burnett D, Campbell EJ.
    Am J Respir Cell Mol Biol; 1990 Mar 30; 2(3):263-9. PubMed ID: 2310584
    [Abstract] [Full Text] [Related]

  • 8. Influence of elastin on the inhibition of leucocyte elastase by alpha 1-proteinase inhibitor and bronchial inhibitor. Potent inhibition of elastin-bound elastase by bronchial inhibitor.
    Bruch M, Bieth JG.
    Biochem J; 1986 Aug 15; 238(1):269-73. PubMed ID: 3492198
    [Abstract] [Full Text] [Related]

  • 9. Effect of different elastase inhibitors on leukocyte elastase pre-adsorbed to elastin.
    Hornebeck W, Schnebli HP.
    Hoppe Seylers Z Physiol Chem; 1982 Apr 15; 363(4):455-8. PubMed ID: 6918355
    [Abstract] [Full Text] [Related]

  • 10. Nonpeptidic inhibitors of human leukocyte elastase. 6. Design of a potent, intratracheally active, pyridone-based trifluoromethyl ketone.
    Bernstein PR, Gomes BC, Kosmider BJ, Vacek EP, Williams JC.
    J Med Chem; 1995 Jan 06; 38(1):212-5. PubMed ID: 7837235
    [Abstract] [Full Text] [Related]

  • 11. Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils.
    Groutas WC, Huang H, Epp JB, Venkataraman R, McClenahan JJ, Tagusagawa F.
    Biochim Biophys Acta; 1994 Nov 29; 1227(3):130-6. PubMed ID: 7986820
    [Abstract] [Full Text] [Related]

  • 12. Improvement of the productivity of elasnin, a specific elastase inhibitor, by Streptomyces noboritoensis KM-2753.
    Ohno H, Yoshida M, Takahashi Y, Omura S.
    J Antibiot (Tokyo); 1980 May 29; 33(5):474-9. PubMed ID: 6903571
    [Abstract] [Full Text] [Related]

  • 13. Nonpeptidic inhibitors of human leukocyte elastase. 3. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of orally active 3-amino-6-phenylpyridin-2-one trifluoromethyl ketones.
    Bernstein PR, Andisik D, Bradley PK, Bryant CB, Ceccarelli C, Damewood JR, Earley R, Edwards PD, Feeney S, Gomes BC.
    J Med Chem; 1994 Sep 30; 37(20):3313-26. PubMed ID: 7932559
    [Abstract] [Full Text] [Related]

  • 14. 3-(Alkylthio)-N-hydroxysuccinimide derivatives: potent inhibitors of human leukocyte elastase.
    Groutas WC, Venkataraman R, Brubaker MJ, Epp JB, Chong LS, Stanga MA, McClenahan JJ, Tagusagawa F.
    Biochim Biophys Acta; 1993 Aug 07; 1164(3):283-8. PubMed ID: 8343527
    [Abstract] [Full Text] [Related]

  • 15. Isolation and characterization of elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces.
    Ohno H, Saheki T, Awaya J, Nakagawa A, Omura S.
    J Antibiot (Tokyo); 1978 Nov 07; 31(11):1116-23. PubMed ID: 721707
    [Abstract] [Full Text] [Related]

  • 16. Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.
    Zembower DE, Kam CM, Powers JC, Zalkow LH.
    J Med Chem; 1992 May 01; 35(9):1597-605. PubMed ID: 1578486
    [Abstract] [Full Text] [Related]

  • 17. Substituted 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides: a new class of potential mechanism-based inhibitors of human leukocyte elastase and cathepsin G.
    Groutas WC, Kuang R, Venkataraman R.
    Biochem Biophys Res Commun; 1994 Jan 14; 198(1):341-9. PubMed ID: 8292039
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of human leukocyte elastase by N-substituted tripeptide trifluoromethyl ketones.
    Skiles JW, Fuchs V, Chow G, Skoog M.
    Res Commun Chem Pathol Pharmacol; 1990 Jun 14; 68(3):365-74. PubMed ID: 2385759
    [Abstract] [Full Text] [Related]

  • 19. Prevention of some types of inflammatory damage using AA 231-1, a fluorinated beta-lactam.
    Reboud-Ravaux M, Vergely I, Maillard J, Favreau C, Kobaiter R, Joyeau R, Wakselman M.
    Drugs Exp Clin Res; 1992 Jun 14; 18(5):159-62. PubMed ID: 1490431
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of tripeptide amide derivatives and examination of their inhibitory effect on human leukocyte elastase (HLE).
    Tsuda Y, Teno N, Okada Y, Nagamatsu Y, Okamoto U.
    Chem Pharm Bull (Tokyo); 1988 Aug 14; 36(8):3119-24. PubMed ID: 3240518
    [No Abstract] [Full Text] [Related]

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