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Journal Abstract Search

150 related items for PubMed ID: 38517197

  • 21. Inhibition of squalene epoxidase linking with PI3K/AKT signaling pathway suppresses endometrial cancer.
    Ma L, Huang W, Liang X, Bai G, Wang X, Jiang H, Xin Y, Hu L, Chen X, Liu C.
    Cancer Sci; 2023 Sep; 114(9):3595-3607. PubMed ID: 37438885
    [Abstract] [Full Text] [Related]

  • 22. Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal-regulated kinase signaling.
    Ge H, Zhao Y, Shi X, Tan Z, Chi X, He M, Jiang G, Ji L, Li H.
    Thorac Cancer; 2019 Mar; 10(3):428-436. PubMed ID: 30734525
    [Abstract] [Full Text] [Related]

  • 23. Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
    Zhang Z, Wu W, Jiao H, Chen Y, Ji X, Cao J, Yin F, Yin W.
    Br J Pharmacol; 2023 Jun; 180(12):1562-1581. PubMed ID: 36581319
    [Abstract] [Full Text] [Related]

  • 24. OSBPL2 deficiency upregulate SQLE expression increasing intracellular cholesterol and cholesteryl ester by AMPK/SP1 and SREBF2 signalling pathway.
    Zhang C, Zhang H, Zhang M, Lin C, Wang H, Yao J, Wei Q, Lu Y, Chen Z, Xing G, Cao X.
    Exp Cell Res; 2019 Oct 15; 383(2):111512. PubMed ID: 31356817
    [Abstract] [Full Text] [Related]

  • 25. Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase.
    Padyana AK, Gross S, Jin L, Cianchetta G, Narayanaswamy R, Wang F, Wang R, Fang C, Lv X, Biller SA, Dang L, Mahoney CE, Nagaraja N, Pirman D, Sui Z, Popovici-Muller J, Smolen GA.
    Nat Commun; 2019 Jan 09; 10(1):97. PubMed ID: 30626872
    [Abstract] [Full Text] [Related]

  • 26. p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth.
    Sun H, Li L, Li W, Yang F, Zhang Z, Liu Z, Du W.
    EMBO Rep; 2021 Oct 05; 22(10):e52537. PubMed ID: 34459531
    [Abstract] [Full Text] [Related]

  • 27. SQLE is a promising prognostic and immunological biomarker and correlated with immune Infiltration in Sarcoma.
    Shao M, Wang M, Wang X, Feng X, Zhang L, Lv H.
    Medicine (Baltimore); 2024 Feb 09; 103(6):e37030. PubMed ID: 38335381
    [Abstract] [Full Text] [Related]

  • 28. Squalene monooxygenase (SQLE) protects ovarian cancer cells from ferroptosis.
    Zhang R, Zhang L, Fan S, Wang L, Wang B, Wang L.
    Sci Rep; 2024 Sep 30; 14(1):22646. PubMed ID: 39349544
    [Abstract] [Full Text] [Related]

  • 29. Knockdown of SQLE promotes CD8+ T cell infiltration in the tumor microenvironment.
    Wu J, Hu W, Yang W, Long Y, Chen K, Li F, Ma X, Li X.
    Cell Signal; 2024 Feb 30; 114():110983. PubMed ID: 37993027
    [Abstract] [Full Text] [Related]

  • 30. Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
    Zhao X, Guo B, Sun W, Yu J, Cui L.
    Adv Sci (Weinh); 2023 Sep 30; 10(27):e2206878. PubMed ID: 37490552
    [Abstract] [Full Text] [Related]

  • 31. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
    Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A.
    Nat Commun; 2021 Aug 20; 12(1):5066. PubMed ID: 34417456
    [Abstract] [Full Text] [Related]

  • 32. SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
    Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y.
    Cell Death Dis; 2023 Aug 04; 14(8):497. PubMed ID: 37542052
    [Abstract] [Full Text] [Related]

  • 33. Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target.
    Liu D, Wong CC, Fu L, Chen H, Zhao L, Li C, Zhou Y, Zhang Y, Xu W, Yang Y, Wu B, Cheng G, Lai PB, Wong N, Sung JJY, Yu J.
    Sci Transl Med; 2018 Apr 18; 10(437):. PubMed ID: 29669855
    [Abstract] [Full Text] [Related]

  • 34. The shape of human squalene epoxidase expands the arsenal against cancer.
    Brown AJ, Chua NK, Yan N.
    Nat Commun; 2019 Feb 21; 10(1):888. PubMed ID: 30792392
    [Abstract] [Full Text] [Related]

  • 35. SCD1 promotes the stemness of gastric cancer stem cells by inhibiting ferroptosis through the SQLE/cholesterol/mTOR signalling pathway.
    Mao X, Wang L, Chen Z, Huang H, Chen J, Su J, Li Z, Shen G, Ren Y, Li Z, Wang W, Ou J, Guo W, Hu Y.
    Int J Biol Macromol; 2024 Aug 21; 275(Pt 2):133698. PubMed ID: 38972654
    [Abstract] [Full Text] [Related]

  • 36. Squalene epoxidase plays a critical role in determining pig meat quality by regulating adipogenesis, myogenesis, and ROS scavengers.
    Ha J, Kwon S, Hwang JH, Park DH, Kim TW, Kang DG, Yu GE, Park HC, An SM, Kim CW.
    Sci Rep; 2017 Dec 01; 7(1):16740. PubMed ID: 29196684
    [Abstract] [Full Text] [Related]

  • 37. Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells.
    Sui Z, Zhou J, Cheng Z, Lu P.
    Tumour Biol; 2015 Aug 01; 36(8):6173-9. PubMed ID: 25787749
    [Abstract] [Full Text] [Related]

  • 38. Cholesterol Metabolism and Prostate Cancer Lethality.
    Stopsack KH, Gerke TA, Sinnott JA, Penney KL, Tyekucheva S, Sesso HD, Andersson SO, Andrén O, Cerhan JR, Giovannucci EL, Mucci LA, Rider JR.
    Cancer Res; 2016 Aug 15; 76(16):4785-90. PubMed ID: 27325648
    [Abstract] [Full Text] [Related]

  • 39. Novel Insight into the Role of Squalene Epoxidase (SQLE) Gene in Determining Milk Production Traits in Buffalo.
    Chen C, Hu X, Ahmad MJ, Niu K, Ye T, Liang A, Yang L.
    Int J Mol Sci; 2023 Jan 26; 24(3):. PubMed ID: 36768756
    [Abstract] [Full Text] [Related]

  • 40. A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition.
    Mahoney CE, Pirman D, Chubukov V, Sleger T, Hayes S, Fan ZP, Allen EL, Chen Y, Huang L, Liu M, Zhang Y, McDonald G, Narayanaswamy R, Choe S, Chen Y, Gross S, Cianchetta G, Padyana AK, Murray S, Liu W, Marks KM, Murtie J, Dorsch M, Jin S, Nagaraja N, Biller SA, Roddy T, Popovici-Muller J, Smolen GA.
    Nat Commun; 2019 Jan 09; 10(1):96. PubMed ID: 30626880
    [Abstract] [Full Text] [Related]

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