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PUBMED FOR HANDHELDS

Journal Abstract Search


174 related items for PubMed ID: 3857628

  • 1. O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
    Brent TP, Houghton PJ, Houghton JA.
    Proc Natl Acad Sci U S A; 1985 May; 82(9):2985-9. PubMed ID: 3857628
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  • 2. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
    Dolan ME, Stine L, Mitchell RB, Moschel RC, Pegg AE.
    Cancer Commun; 1990 May; 2(11):371-7. PubMed ID: 2242301
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  • 3. Response of cultured human cell lines from rhabdomyosarcoma xenografts to treatment with chloroethylnitrosoureas.
    Smith DG, Brent TP.
    Cancer Res; 1989 Feb 15; 49(4):883-6. PubMed ID: 2521455
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  • 11. Increased cytotoxicity of 1-(2-chloroethyl)-1-nitroso-3(4-methyl)-cyclohexylurea by pretreatment with O6-methylguanine in resistant but not in sensitive human melanoma cells.
    Dempke W, Nehls P, Wandl U, Soll D, Schmidt CG, Osieka R.
    J Cancer Res Clin Oncol; 1987 Feb 15; 113(4):387-91. PubMed ID: 3597524
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  • 12. Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine.
    Dolan ME, Larkin GL, English HF, Pegg AE.
    Cancer Chemother Pharmacol; 1989 Feb 15; 25(2):103-8. PubMed ID: 2557168
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  • 14. Formation of DNA interstrand cross-links by the novel chloroethylating agent 2-chloroethyl(methylsulfonyl)methanesulfonate: suppression by O6-alkylguanine-DNA alkyltransferase purified from human leukemic lymphoblasts.
    Brent TP, Lestrud SO, Smith DG, Remack JS.
    Cancer Res; 1987 Jul 01; 47(13):3384-7. PubMed ID: 3034412
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  • 15. Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine.
    Gerson SL, Berger NA, Arce C, Petzold SJ, Willson JK.
    Biochem Pharmacol; 1992 Mar 03; 43(5):1101-7. PubMed ID: 1554383
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  • 16. O6-alkylguanine DNA-alkyltransferase is not a major determinant of sensitivity to 1,3-bis(2-chloroethyl)-1-nitrosourea in four medulloblastoma cell lines.
    Silber JR, Bobola MS, Ewers TG, Muramoto M, Berger MS.
    Oncol Res; 1992 Mar 03; 4(6):241-8. PubMed ID: 1421617
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  • 17. O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
    Phillips WP, Willson JK, Markowitz SD, Zborowska E, Zaidi NH, Liu L, Gordon NH, Gerson SL.
    Cancer Res; 1997 Nov 01; 57(21):4817-23. PubMed ID: 9354444
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  • 18. Evidence that O6-alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing 1,3-bis(2-chloroethyl)-1-nitrosourea-induced precursors of interstrand cross-links.
    Brent TP, Smith DG, Remack JS.
    Biochem Biophys Res Commun; 1987 Jan 30; 142(2):341-7. PubMed ID: 3814140
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  • 20. Differential repair of 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea-induced DNA damage in two human colon tumor cell lines.
    Erickson LC, Osieka R, Kohn KW.
    Cancer Res; 1978 Mar 30; 38(3):802-8. PubMed ID: 626984
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