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Journal Abstract Search

119 related items for PubMed ID: 38604611

  • 1. A natural inhibitor of diapophytoene desaturase attenuates methicillin-resistant Staphylococcus aureus (MRSA) pathogenicity and overcomes drug-resistance.
    Han B, Wang H, Niu X.
    Br J Pharmacol; 2024 Aug; 181(15):2583-2599. PubMed ID: 38604611
    [Abstract] [Full Text] [Related]

  • 2. Dehydrosqualene Desaturase as a Novel Target for Anti-Virulence Therapy against Staphylococcus aureus.
    Gao P, Davies J, Kao RYT.
    mBio; 2017 Sep 05; 8(5):. PubMed ID: 28874472
    [Abstract] [Full Text] [Related]

  • 3. Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections.
    Wang Y, Chen F, Di H, Xu Y, Xiao Q, Wang X, Wei H, Lu Y, Zhang L, Zhu J, Sheng C, Lan L, Li J.
    J Med Chem; 2016 Apr 14; 59(7):3215-30. PubMed ID: 26999509
    [Abstract] [Full Text] [Related]

  • 4. Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence.
    Chen F, Di H, Wang Y, Cao Q, Xu B, Zhang X, Yang N, Liu G, Yang CG, Xu Y, Jiang H, Lian F, Zhang N, Li J, Lan L.
    Nat Chem Biol; 2016 Mar 14; 12(3):174-9. PubMed ID: 26780405
    [Abstract] [Full Text] [Related]

  • 5. Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections.
    Wei H, Mao F, Ni S, Chen F, Li B, Qiu X, Hu L, Wang M, Zheng X, Zhu J, Lan L, Li J.
    Eur J Med Chem; 2018 Feb 10; 145():235-251. PubMed ID: 29328999
    [Abstract] [Full Text] [Related]

  • 6. Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN).
    Wang Y, Di H, Chen F, Xu Y, Xiao Q, Wang X, Wei H, Lu Y, Zhang L, Zhu J, Lan L, Li J.
    J Med Chem; 2016 May 26; 59(10):4831-48. PubMed ID: 27139780
    [Abstract] [Full Text] [Related]

  • 7. Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections.
    Li B, Ni S, Chen F, Mao F, Wei H, Liu Y, Zhu J, Lan L, Li J.
    ACS Infect Dis; 2018 Mar 09; 4(3):208-217. PubMed ID: 29377669
    [Abstract] [Full Text] [Related]

  • 8. Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus.
    Sakai K, Koyama N, Fukuda T, Mori Y, Onaka H, Tomoda H.
    Biol Pharm Bull; 2012 Mar 09; 35(1):48-53. PubMed ID: 22223336
    [Abstract] [Full Text] [Related]

  • 9. Antibiofilm and staphyloxanthin inhibitory potential of terbinafine against Staphylococcus aureus: in vitro and in vivo studies.
    Askoura M, Yousef N, Mansour B, Yehia FAA.
    Ann Clin Microbiol Antimicrob; 2022 May 30; 21(1):21. PubMed ID: 35637481
    [Abstract] [Full Text] [Related]

  • 10. Hesperidin inhibits biofilm formation, virulence and staphyloxanthin synthesis in methicillin resistant Staphylococcus aureus by targeting SarA and CrtM: an in vitro and in silico approach.
    Vijayakumar K, Muhilvannan S, Arun Vignesh M.
    World J Microbiol Biotechnol; 2022 Jan 22; 38(3):44. PubMed ID: 35064842
    [Abstract] [Full Text] [Related]

  • 11. Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
    Li B, Ni S, Mao F, Chen F, Liu Y, Wei H, Chen W, Zhu J, Lan L, Li J.
    J Med Chem; 2018 Jan 11; 61(1):224-250. PubMed ID: 29243920
    [Abstract] [Full Text] [Related]

  • 12. Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo.
    Ni S, Wei H, Li B, Chen F, Liu Y, Chen W, Xu Y, Qiu X, Li X, Lu Y, Liu W, Hu L, Lin D, Wang M, Zheng X, Mao F, Zhu J, Lan L, Li J.
    J Med Chem; 2017 Oct 12; 60(19):8145-8159. PubMed ID: 28880552
    [Abstract] [Full Text] [Related]

  • 13. Staphyloxanthin inhibitory potential of thymol impairs antioxidant fitness, enhances neutrophil mediated killing and alters membrane fluidity of methicillin resistant Staphylococcus aureus.
    Valliammai A, Selvaraj A, Muthuramalingam P, Priya A, Ramesh M, Pandian SK.
    Biomed Pharmacother; 2021 Sep 12; 141():111933. PubMed ID: 34328107
    [Abstract] [Full Text] [Related]

  • 14. Protective Effect of the Golden Staphyloxanthin Biosynthesis Pathway on Staphylococcus aureus under Cold Atmospheric Plasma Treatment.
    Yang Y, Wang H, Zhou H, Hu Z, Shang W, Rao Y, Peng H, Zheng Y, Hu Q, Zhang R, Luo H, Rao X.
    Appl Environ Microbiol; 2020 Jan 21; 86(3):. PubMed ID: 31704682
    [Abstract] [Full Text] [Related]

  • 15. Small-molecule compound SYG-180-2-2 attenuates Staphylococcus aureus virulence by inhibiting hemolysin and staphyloxanthin production.
    Rao L, Xu Y, Shen L, Wang X, Zhao H, Wang B, Zhang J, Xiao Y, Guo Y, Sheng Y, Cheng L, Song Z, Yu F.
    Front Cell Infect Microbiol; 2022 Jan 21; 12():1008289. PubMed ID: 36310881
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus.
    Jin J, Cui J, Chaudhary AS, Hsieh YH, Damera K, Zhang H, Yang H, Wang B, Tai PC.
    Bioorg Med Chem; 2015 Nov 01; 23(21):7061-8. PubMed ID: 26432604
    [Abstract] [Full Text] [Related]

  • 17. Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics.
    Tan CM, Therien AG, Lu J, Lee SH, Caron A, Gill CJ, Lebeau-Jacob C, Benton-Perdomo L, Monteiro JM, Pereira PM, Elsen NL, Wu J, Deschamps K, Petcu M, Wong S, Daigneault E, Kramer S, Liang L, Maxwell E, Claveau D, Vaillancourt J, Skorey K, Tam J, Wang H, Meredith TC, Sillaots S, Wang-Jarantow L, Ramtohul Y, Langlois E, Landry F, Reid JC, Parthasarathy G, Sharma S, Baryshnikova A, Lumb KJ, Pinho MG, Soisson SM, Roemer T.
    Sci Transl Med; 2012 Mar 21; 4(126):126ra35. PubMed ID: 22440737
    [Abstract] [Full Text] [Related]

  • 18. Diphenylurea derivatives for combating methicillin- and vancomycin-resistant Staphylococcus aureus.
    Eissa IH, Mohammad H, Qassem OA, Younis W, Abdelghany TM, Elshafeey A, Abd Rabo Moustafa MM, Seleem MN, Mayhoub AS.
    Eur J Med Chem; 2017 Apr 21; 130():73-85. PubMed ID: 28249208
    [Abstract] [Full Text] [Related]

  • 19. MSI-1 combats drug-resistant S. aureus by affecting bacterial viability and inhibiting carotenoid pigment production.
    Ye X, Huang Y, Zhou C, Liu X, Zhao W, Zhao X, Xie X, Wang L, Bai Z, Zhou C, Ma L.
    Microbiol Res; 2021 Oct 27; 255():126909. PubMed ID: 34839171
    [Abstract] [Full Text] [Related]

  • 20. Berberine hydrochloride reduces staphyloxanthin synthesis by inhibiting fni genes in methicillin-resistant Staphylococcus aureus.
    Qiu M, Xu Z.
    Mol Biol Rep; 2024 Jun 14; 51(1):761. PubMed ID: 38874884
    [Abstract] [Full Text] [Related]

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