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201 related items for PubMed ID: 3871240

  • 1. Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?
    Irwin I, Langston JW.
    Life Sci; 1985 Jan 21; 36(3):207-12. PubMed ID: 3871240
    [Abstract] [Full Text] [Related]

  • 2. Pargyline prevents MPTP-induced parkinsonism in primates.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Science; 1984 Sep 28; 225(4669):1480-2. PubMed ID: 6332378
    [Abstract] [Full Text] [Related]

  • 3. 1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Neurosci Lett; 1984 Jul 13; 48(1):87-92. PubMed ID: 6332288
    [Abstract] [Full Text] [Related]

  • 4. Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes.
    Di Monte D, Ekström G, Shinka T, Smith MT, Trevor AJ, Castagnoli N.
    Chem Biol Interact; 1987 Jul 13; 62(2):105-16. PubMed ID: 3496169
    [Abstract] [Full Text] [Related]

  • 5. Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+.
    Ransom BR, Kunis DM, Irwin I, Langston JW.
    Neurosci Lett; 1987 Apr 10; 75(3):323-8. PubMed ID: 3495754
    [Abstract] [Full Text] [Related]

  • 6. The importance of the '4-5' double bond for neurotoxicity in primates of the pyridine derivative MPTP.
    Langston JW, Irwin I, Langston EB, Forno LS.
    Neurosci Lett; 1984 Sep 07; 50(1-3):289-94. PubMed ID: 6333656
    [Abstract] [Full Text] [Related]

  • 7. Processing of MPTP by monoamine oxidases: implications for molecular toxicology.
    Trevor AJ, Singer TP, Ramsay RR, Castagnoli N.
    J Neural Transm Suppl; 1987 Sep 07; 23():73-89. PubMed ID: 3295117
    [Abstract] [Full Text] [Related]

  • 8. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae.
    Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP.
    Life Sci; 1987 Feb 23; 40(8):713-9. PubMed ID: 3492651
    [Abstract] [Full Text] [Related]

  • 9. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway.
    Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ.
    Nature; 1987 Feb 23; 319(6048):56-7. PubMed ID: 3484542
    [Abstract] [Full Text] [Related]

  • 10. Neuromelanin: a role in MPTP-induced neurotoxicity.
    D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt CA, Price DL, Snyder SH.
    Life Sci; 1987 Feb 23; 40(8):705-12. PubMed ID: 2880274
    [Abstract] [Full Text] [Related]

  • 11. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Bradbury AJ, Costall B, Domeney AM, Testa B, Jenner PG, Marsden CD, Naylor RJ.
    Neurosci Lett; 1985 Oct 24; 61(1-2):121-6. PubMed ID: 2417166
    [Abstract] [Full Text] [Related]

  • 12. Characterization of the binding of N-methyl-4-phenylpyridine, the toxic metabolite of the parkinsonian neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, to neuromelanin.
    D'Amato RJ, Benham DF, Snyder SH.
    J Neurochem; 1987 Feb 24; 48(2):653-8. PubMed ID: 3491879
    [Abstract] [Full Text] [Related]

  • 13. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
    [Abstract] [Full Text] [Related]

  • 14. The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
    Jenner P, Marsden CD.
    J Neural Transm Suppl; 1986 Dec 18; 20():11-39. PubMed ID: 3091760
    [Abstract] [Full Text] [Related]

  • 15. Selectivity of the parkinsonian neurotoxin MPTP: toxic metabolite MPP+ binds to neuromelanin.
    D'Amato RJ, Lipman ZP, Snyder SH.
    Science; 1986 Feb 28; 231(4741):987-9. PubMed ID: 3080808
    [Abstract] [Full Text] [Related]

  • 16. MPTP-induced parkinsonism in human and non-human primates--clinical and experimental aspects.
    Langston JW, Langston EB, Irwin I.
    Acta Neurol Scand Suppl; 1984 Feb 28; 100():49-54. PubMed ID: 6333134
    [Abstract] [Full Text] [Related]

  • 17. Studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Cohen G, Mytilineou C.
    Life Sci; 1985 Jan 21; 36(3):237-42. PubMed ID: 3917526
    [Abstract] [Full Text] [Related]

  • 18. Comparative toxicity of MPTP, MPP+ and 3,3-dimethyl-MPDP+ to dopaminergic neurons of the rat substantia nigra.
    Sayre LM, Arora PK, Iacofano LA, Harik SI.
    Eur J Pharmacol; 1986 May 13; 124(1-2):171-4. PubMed ID: 3487462
    [Abstract] [Full Text] [Related]

  • 19. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat.
    Harik SI, Schmidley JW, Iacofano LA, Blue P, Arora PK, Sayre LM.
    J Pharmacol Exp Ther; 1987 May 13; 241(2):669-76. PubMed ID: 2437293
    [Abstract] [Full Text] [Related]

  • 20. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Castagnoli N, Chiba K, Trevor AJ.
    Life Sci; 1985 Jan 21; 36(3):225-30. PubMed ID: 3871243
    [Abstract] [Full Text] [Related]

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