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Journal Abstract Search

127 related items for PubMed ID: 38735046

  • 1. The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells.
    Wang T, Guo J, Liping Li, Jin Q, Zhang F, Hou B, Zhang Y, Zhou X.
    Cell Rep; 2024 May 28; 43(5):114222. PubMed ID: 38735046
    [Abstract] [Full Text] [Related]

  • 2. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
    Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A.
    Mol Cell Biol; 2009 Nov 28; 29(22):6074-85. PubMed ID: 19703992
    [Abstract] [Full Text] [Related]

  • 3. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
    Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.
    J Biol Chem; 2014 Jan 10; 289(2):868-84. PubMed ID: 24235145
    [Abstract] [Full Text] [Related]

  • 4. Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance.
    Huo H, Magro PG, Pietsch EC, Patel BB, Scotto KW.
    Cancer Res; 2010 Nov 01; 70(21):8726-35. PubMed ID: 20861184
    [Abstract] [Full Text] [Related]

  • 5. On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
    Patel A, Dharmarajan V, Vought VE, Cosgrove MS.
    J Biol Chem; 2009 Sep 04; 284(36):24242-56. PubMed ID: 19556245
    [Abstract] [Full Text] [Related]

  • 6. Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.
    Wiersma M, Bussiere M, Halsall JA, Turan N, Slany R, Turner BM, Nightingale KP.
    Epigenetics Chromatin; 2016 Sep 04; 9():52. PubMed ID: 27895715
    [Abstract] [Full Text] [Related]

  • 7. The histone methyltransferase MLL1 permits the oscillation of circadian gene expression.
    Katada S, Sassone-Corsi P.
    Nat Struct Mol Biol; 2010 Dec 04; 17(12):1414-21. PubMed ID: 21113167
    [Abstract] [Full Text] [Related]

  • 8. The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.
    Carson WF, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL.
    J Immunol; 2017 Sep 01; 199(5):1865-1874. PubMed ID: 28733487
    [Abstract] [Full Text] [Related]

  • 9. Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.
    Jakovcevski M, Ruan H, Shen EY, Dincer A, Javidfar B, Ma Q, Peter CJ, Cheung I, Mitchell AC, Jiang Y, Lin CL, Pothula V, Stewart AF, Ernst P, Yao WD, Akbarian S.
    J Neurosci; 2015 Apr 01; 35(13):5097-108. PubMed ID: 25834037
    [Abstract] [Full Text] [Related]

  • 10. Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts.
    Okamoto K, Araki Y, Aizaki Y, Tanaka S, Kadono Y, Mimura T.
    Sci Rep; 2024 May 09; 14(1):10610. PubMed ID: 38719857
    [Abstract] [Full Text] [Related]

  • 11. miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.
    Sengupta D, Deb M, Kar S, Parbin S, Pradhan N, Patra SK.
    Gene; 2019 Jul 15; 705():22-35. PubMed ID: 31005612
    [Abstract] [Full Text] [Related]

  • 12. Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.
    Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y.
    Mol Cell; 2014 Jan 23; 53(2):247-61. PubMed ID: 24389101
    [Abstract] [Full Text] [Related]

  • 13. The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis.
    Mishra BP, Zaffuto KM, Artinger EL, Org T, Mikkola HK, Cheng C, Djabali M, Ernst P.
    Cell Rep; 2014 May 22; 7(4):1239-47. PubMed ID: 24813891
    [Abstract] [Full Text] [Related]

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  • 17. Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
    Dharmarajan V, Lee JH, Patel A, Skalnik DG, Cosgrove MS.
    J Biol Chem; 2012 Aug 10; 287(33):27275-89. PubMed ID: 22665483
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  • 19. The MLL1-H3K4me3 Axis-Mediated PD-L1 Expression and Pancreatic Cancer Immune Evasion.
    Lu C, Paschall AV, Shi H, Savage N, Waller JL, Sabbatini ME, Oberlies NH, Pearce C, Liu K.
    J Natl Cancer Inst; 2017 Jan 10; 109(6):. PubMed ID: 28131992
    [Abstract] [Full Text] [Related]

  • 20. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer.
    Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, Vidal RO, Sunaga-Franze DY, Müller M, Wulf-Goldenberg A, Sauer S, Birchmeier W.
    Cell Rep; 2019 Jan 08; 26(2):415-428.e5. PubMed ID: 30625324
    [Abstract] [Full Text] [Related]

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