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199 related items for PubMed ID: 38750673

  • 1. Cerebellar Heterogeneity and Selective vulnerability in Spinocerebellar Ataxia Type 1 (SCA1).
    Hamel K, Moncada EL, Sheeler C, Rosa JG, Gilliat S, Zhang Y, Cvetanovic M.
    Neurobiol Dis; 2024 Jul; 197():106530. PubMed ID: 38750673
    [Abstract] [Full Text] [Related]

  • 2. Altered calcium signaling in Bergmann glia contributes to spinocerebellar ataxia type-1 in a mouse model of SCA1.
    Nanclares C, Noriega-Prieto JA, Labrada-Moncada FE, Cvetanovic M, Araque A, Kofuji P.
    Neurobiol Dis; 2023 Oct 15; 187():106318. PubMed ID: 37802154
    [Abstract] [Full Text] [Related]

  • 3. Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1.
    Luttik K, Tejwani L, Ju H, Driessen T, Smeets CJLM, Edamakanti CR, Khan A, Yun J, Opal P, Lim J.
    Proc Natl Acad Sci U S A; 2022 Aug 23; 119(34):e2208513119. PubMed ID: 35969780
    [Abstract] [Full Text] [Related]

  • 4. Memantine suppresses the excitotoxicity but fails to rescue the ataxic phenotype in SCA1 model mice.
    Belozor OS, Vasilev A, Mileiko AG, Mosina LD, Mikhailov IG, Ox DA, Boitsova EB, Shuvaev AN, Teschemacher AG, Kasparov S, Shuvaev AN.
    Biomed Pharmacother; 2024 May 23; 174():116526. PubMed ID: 38574621
    [Abstract] [Full Text] [Related]

  • 5. Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1.
    Chopra R, Bushart DD, Cooper JP, Yellajoshyula D, Morrison LM, Huang H, Handler HP, Man LJ, Dansithong W, Scoles DR, Pulst SM, Orr HT, Shakkottai VG.
    Hum Mol Genet; 2020 Nov 25; 29(19):3249-3265. PubMed ID: 32964235
    [Abstract] [Full Text] [Related]

  • 6. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
    Shuvaev AN, Belozor OS, Mozhei OI, Shuvaev AN, Fritsler YV, Khilazheva ED, Mosyagina AI, Hirai H, Teschemacher AG, Kasparov S.
    Cells; 2022 Jul 20; 11(14):. PubMed ID: 35883691
    [Abstract] [Full Text] [Related]

  • 7. Identifying Disease Signatures in the Spinocerebellar Ataxia Type 1 Mouse Cortex.
    Luttik K, Olmos V, Owens A, Khan A, Yun J, Driessen T, Lim J.
    Cells; 2022 Aug 24; 11(17):. PubMed ID: 36078042
    [Abstract] [Full Text] [Related]

  • 8. Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy.
    Vig PJ, Hearst S, Shao Q, Lopez ME, Murphy HA, Safaya E.
    Cerebellum; 2011 Jun 24; 10(2):254-66. PubMed ID: 21384195
    [Abstract] [Full Text] [Related]

  • 9. Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1.
    Emir UE, Brent Clark H, Vollmers ML, Eberly LE, Öz G.
    J Neurochem; 2013 Dec 24; 127(5):660-8. PubMed ID: 24032423
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice.
    Qu W, Johnson A, Kim JH, Lukowicz A, Svedberg D, Cvetanovic M.
    J Neuroinflammation; 2017 May 25; 14(1):107. PubMed ID: 28545543
    [Abstract] [Full Text] [Related]

  • 11. BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1.
    Rosa JG, Hamel K, Soles A, Sheeler C, Borgenheimer E, Gilliat S, Sbrocco K, Ghanoum F, Handler HP, Forster C, Rainwater O, Cvetanovic M.
    Neurobiol Dis; 2023 Mar 25; 178():106023. PubMed ID: 36724861
    [Abstract] [Full Text] [Related]

  • 12. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.
    Edamakanti CR, Do J, Didonna A, Martina M, Opal P.
    J Clin Invest; 2018 Jun 01; 128(6):2252-2265. PubMed ID: 29533923
    [Abstract] [Full Text] [Related]

  • 13. Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice.
    Blot FGC, Krijnen WHJJ, Den Hoedt S, Osório C, White JJ, Mulder MT, Schonewille M.
    Proc Natl Acad Sci U S A; 2021 Sep 07; 118(36):. PubMed ID: 34479994
    [Abstract] [Full Text] [Related]

  • 14. Purkinje cell COX deficiency and mtDNA depletion in an animal model of spinocerebellar ataxia type 1.
    Ripolone M, Lucchini V, Ronchi D, Fagiolari G, Bordoni A, Fortunato F, Mondello S, Bonato S, Meregalli M, Torrente Y, Corti S, Comi GP, Moggio M, Sciacco M.
    J Neurosci Res; 2018 Sep 07; 96(9):1576-1585. PubMed ID: 30113722
    [Abstract] [Full Text] [Related]

  • 15. Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1.
    Driessen TM, Lee PJ, Lim J.
    Elife; 2018 Dec 03; 7():. PubMed ID: 30507379
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.
    Notartomaso S, Zappulla C, Biagioni F, Cannella M, Bucci D, Mascio G, Scarselli P, Fazio F, Weisz F, Lionetto L, Simmaco M, Gradini R, Battaglia G, Signore M, Puliti A, Nicoletti F.
    Mol Brain; 2013 Nov 19; 6():48. PubMed ID: 24252411
    [Abstract] [Full Text] [Related]

  • 17. Chronic optogenetic stimulation of Bergman glia leads to dysfunction of EAAT1 and Purkinje cell death, mimicking the events caused by expression of pathogenic ataxin-1.
    Shuvaev AN, Belozor OS, Mozhei O, Yakovleva DA, Potapenko IV, Shuvaev AN, Smolnikova MV, Salmin VV, Salmina AB, Hirai H, Teschemacher AG, Kasparov S.
    Neurobiol Dis; 2021 Jul 19; 154():105340. PubMed ID: 33753288
    [Abstract] [Full Text] [Related]

  • 18. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
    Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT.
    Neuron; 2018 Mar 21; 97(6):1235-1243.e5. PubMed ID: 29526553
    [Abstract] [Full Text] [Related]

  • 19. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models.
    Asher M, Rosa JG, Rainwater O, Duvick L, Bennyworth M, Lai RY, CRC-SCA, Kuo SH, Cvetanovic M.
    Hum Mol Genet; 2020 Jan 01; 29(1):117-131. PubMed ID: 31696233
    [Abstract] [Full Text] [Related]

  • 20. SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2.
    Niewiadomska-Cimicka A, Doussau F, Perot JB, Roux MJ, Keime C, Hache A, Piguet F, Novati A, Weber C, Yalcin B, Meziane H, Champy MF, Grandgirard E, Karam A, Messaddeq N, Eisenmann A, Brouillet E, Nguyen HHP, Flament J, Isope P, Trottier Y.
    J Neurosci; 2021 Jun 02; 41(22):4910-4936. PubMed ID: 33888607
    [Abstract] [Full Text] [Related]

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