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Journal Abstract Search

154 related items for PubMed ID: 38751223

  • 1. Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment.
    Abdel-Motaal M, Aldakhili DA, Abo Elmaaty A, Sharaky M, Mourad MAE, Alzahrani AYA, Mohamed NA, Al-Karmalawy AA.
    Drug Dev Res; 2024 Jun; 85(4):e22197. PubMed ID: 38751223
    [Abstract] [Full Text] [Related]

  • 2. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 3. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
    Ranjan Dwivedi A, Kumar V, Kaur H, Kumar N, Prakash Yadav R, Poduri R, Baranwal S, Kumar V.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127468. PubMed ID: 32768647
    [Abstract] [Full Text] [Related]

  • 4. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Jul 15; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies.
    Hammouda MM, Elmaaty AA, Nafie MS, Abdel-Motaal M, Mohamed NS, Tantawy MA, Belal A, Alnajjar R, Eldehna WM, Al-Karmalawy AA.
    Bioorg Chem; 2022 Oct 15; 127():105995. PubMed ID: 35792315
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2020 Dec 15; 35(1):139-144. PubMed ID: 31724435
    [Abstract] [Full Text] [Related]

  • 8. Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.
    Abdel-Motaal M, Aldakhili DA, Farag AB, Elmaaty AA, Sharaky M, Mohamed NA, Shaaban S, Alzahrani AYA, Al-Karmalawy AA.
    RSC Med Chem; 2024 Aug 30; 15(11):3800-16. PubMed ID: 39290384
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 30; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY.
    Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors.
    Baytas SN, Inceler N, Yilmaz A, Olgac A, Menevse S, Banoglu E, Hamel E, Bortolozzi R, Viola G.
    Bioorg Med Chem; 2014 Jun 15; 22(12):3096-104. PubMed ID: 24816066
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G, Liu W, Fan M, He M, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):1694-1702. PubMed ID: 34309466
    [Abstract] [Full Text] [Related]

  • 13. Novel HDAC/Tubulin Dual Inhibitor: Design, Synthesis and Docking Studies of α-Phthalimido-Chalcone Hybrids as Potential Anticancer Agents with Apoptosis-Inducing Activity.
    Mourad AAE, Mourad MAE, Jones PG.
    Drug Des Devel Ther; 2020 Dec 15; 14():3111-3130. PubMed ID: 32848361
    [Abstract] [Full Text] [Related]

  • 14. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
    Rahimzadeh Oskuei S, Mirzaei S, Reza Jafari-Nik M, Hadizadeh F, Eisvand F, Mosaffa F, Ghodsi R.
    Bioorg Chem; 2021 Jul 01; 112():104904. PubMed ID: 33933802
    [Abstract] [Full Text] [Related]

  • 16. Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colchicine binding site inhibitors.
    Yao Y, Huang T, Wang Y, Wang L, Feng S, Cheng W, Yang L, Duan Y.
    J Enzyme Inhib Med Chem; 2022 Dec 01; 37(1):652-665. PubMed ID: 35109719
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 01; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 18. Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition study.
    Sigalapalli DK, Pooladanda V, Singh P, Kadagathur M, Guggilapu SD, Uppu JL, Tangellamudi ND, Gangireddy PK, Godugu C, Bathini NB.
    Bioorg Chem; 2019 Nov 01; 92():103188. PubMed ID: 31450167
    [Abstract] [Full Text] [Related]

  • 19. Discovery of novel octahydroquinazoline scaffolds endowed with dual inhibition of tubulin polymerization/Eg5 against HCC: Apoptotic and radio-chemotherapeutic studies.
    Abdelhameid MK, Taher ES, Hara MA, Ramadan M, Mohamed KO.
    Bioorg Chem; 2024 Jul 01; 148():107449. PubMed ID: 38759356
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S, Tokala R, Bajaj DM, Nagesh N, Bokara KK, Kiranmai G, Lakshmi UJ, Vadlamani S, Talla V, Shankaraiah N.
    Bioorg Chem; 2019 Dec 01; 93():103317. PubMed ID: 31586714
    [Abstract] [Full Text] [Related]

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