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126 related items for PubMed ID: 3875812

  • 1. 1-Methyl-4-phenylpyridine (MPP+) is toxic to mesencephalic dopamine neurons in culture.
    Mytilineou C, Cohen G, Heikkila RE.
    Neurosci Lett; 1985 Jun 04; 57(1):19-24. PubMed ID: 3875812
    [Abstract] [Full Text] [Related]

  • 2. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon.
    Schinelli S, Zuddas A, Kopin IJ, Barker JL, di Porzio U.
    J Neurochem; 1988 Jun 04; 50(6):1900-7. PubMed ID: 3259619
    [Abstract] [Full Text] [Related]

  • 3. Mesencephalic dopamine neurons become less sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity during development in vitro.
    Danias P, Nicklas WJ, Ofori S, Shen J, Mytilineou C.
    J Neurochem; 1989 Oct 04; 53(4):1149-55. PubMed ID: 2788714
    [Abstract] [Full Text] [Related]

  • 4. FGF-2-mediated protection of cultured mesencephalic dopaminergic neurons against MPTP and MPP+: specificity and impact of culture conditions, non-dopaminergic neurons, and astroglial cells.
    Otto D, Unsicker K.
    J Neurosci Res; 1993 Mar 01; 34(4):382-93. PubMed ID: 8097265
    [Abstract] [Full Text] [Related]

  • 5. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Bradbury AJ, Costall B, Domeney AM, Testa B, Jenner PG, Marsden CD, Naylor RJ.
    Neurosci Lett; 1985 Oct 24; 61(1-2):121-6. PubMed ID: 2417166
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  • 9. 1-methyl-4-phenylpyridine is neurotoxic to the nigrostriatal dopamine pathway.
    Bradbury AJ, Costall B, Domeney AM, Jenner P, Kelly ME, Marsden CD, Naylor RJ.
    Nature; 1985 Oct 24; 319(6048):56-7. PubMed ID: 3484542
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  • 10. Tissue culture model for studying MPTP toxicity to dopamine neurons.
    Mytilineou C, Cohen G.
    Adv Neurol; 1987 Oct 24; 45():145-8. PubMed ID: 3493622
    [No Abstract] [Full Text] [Related]

  • 11. Deprenyl protects dopamine neurons from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion.
    Mytilineou C, Cohen G.
    J Neurochem; 1985 Dec 24; 45(6):1951-3. PubMed ID: 3932598
    [Abstract] [Full Text] [Related]

  • 12. Comparative toxicity of MPTP, MPP+ and 3,3-dimethyl-MPDP+ to dopaminergic neurons of the rat substantia nigra.
    Sayre LM, Arora PK, Iacofano LA, Harik SI.
    Eur J Pharmacol; 1986 May 13; 124(1-2):171-4. PubMed ID: 3487462
    [Abstract] [Full Text] [Related]

  • 13. On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat.
    Harik SI, Schmidley JW, Iacofano LA, Blue P, Arora PK, Sayre LM.
    J Pharmacol Exp Ther; 1987 May 13; 241(2):669-76. PubMed ID: 2437293
    [Abstract] [Full Text] [Related]

  • 14. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
    [Abstract] [Full Text] [Related]

  • 15. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.
    Javitch JA, D'Amato RJ, Strittmatter SM, Snyder SH.
    Proc Natl Acad Sci U S A; 1985 Apr 18; 82(7):2173-7. PubMed ID: 3872460
    [Abstract] [Full Text] [Related]

  • 16. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity.
    Sershen H, Mason MF, Debler EA, Lajtha A.
    Eur J Pharmacol; 1986 Jul 31; 126(3):337-9. PubMed ID: 3489627
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  • 17. 4-Phenylpyridine (4PP) and MPTP: the relationship between striatal MPP+ concentrations and neurotoxicity.
    Irwin I, Langston JW, DeLanney LE.
    Life Sci; 1987 Feb 23; 40(8):731-40. PubMed ID: 3492652
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  • 18. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine destroys dopamine neurons in explants of rat embryo mesencephalon.
    Mytilineou C, Cohen G.
    Science; 1984 Aug 03; 225(4661):529-31. PubMed ID: 6610939
    [Abstract] [Full Text] [Related]

  • 19. Functional changes in cocultures of mesencephalon and striatal neurons from embryonic C57/BL6 mice due to low concentrations of 1-methyl-4-phenylpyridinium (MPP+).
    Koutsilieri E, Chan WW, Reinitzer D, Rausch WD.
    J Neural Transm Gen Sect; 1993 Aug 03; 94(3):189-97. PubMed ID: 7907217
    [Abstract] [Full Text] [Related]

  • 20. Effect of MPTP and its pyridinium metabolites on monoamine uptake and on central catecholamine neurons in mice.
    Jonsson G, Nwanze E, Luthman J, Sundström E.
    Acta Physiol Scand; 1986 Oct 03; 128(2):187-94. PubMed ID: 3535380
    [Abstract] [Full Text] [Related]

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