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185 related items for PubMed ID: 38810120

  • 1. Regulation of hepatic xenosensor function by HNF4alpha.
    Kotulkar M, Paine-Cabrera D, Robarts DR, Apte U.
    Toxicol Sci; 2024 Aug 01; 200(2):346-356. PubMed ID: 38810120
    [Abstract] [Full Text] [Related]

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  • 3. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R, Benoki S, Numakura Y, Kodama S, Miyata M, Yamazoe Y, Yoshinari K.
    PLoS One; 2013 Aug 01; 8(4):e61802. PubMed ID: 23626729
    [Abstract] [Full Text] [Related]

  • 4. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
    Buckley DB, Klaassen CD.
    Drug Metab Dispos; 2009 Apr 01; 37(4):847-56. PubMed ID: 19144771
    [Abstract] [Full Text] [Related]

  • 5. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
    Cui JY, Klaassen CD.
    Biochim Biophys Acta; 2016 Sep 01; 1859(9):1198-1217. PubMed ID: 27113289
    [Abstract] [Full Text] [Related]

  • 6. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.
    Aleksunes LM, Klaassen CD.
    Drug Metab Dispos; 2012 Jul 01; 40(7):1366-79. PubMed ID: 22496397
    [Abstract] [Full Text] [Related]

  • 7. Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse.
    Wang Z, Wu Q, Li X, Klaunig JE.
    Arch Toxicol; 2020 Aug 01; 94(8):2873-2884. PubMed ID: 32435917
    [Abstract] [Full Text] [Related]

  • 8. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.
    Haines C, Chatham LR, Vardy A, Elcombe CR, Foster JR, Lake BG.
    Toxicology; 2018 May 01; 400-401():20-27. PubMed ID: 29548889
    [Abstract] [Full Text] [Related]

  • 9. Editor's Highlight: Neonatal Activation of the Xenobiotic-Sensors PXR and CAR Results in Acute and Persistent Down-regulation of PPARα-Signaling in Mouse Liver.
    Li CY, Cheng SL, Bammler TK, Cui JY.
    Toxicol Sci; 2016 Oct 01; 153(2):282-302. PubMed ID: 27413110
    [Abstract] [Full Text] [Related]

  • 10. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
    Tamasi V, Juvan P, Beer M, Rozman D, Meyer UA.
    Mol Pharm; 2009 Oct 01; 6(5):1573-81. PubMed ID: 19708687
    [Abstract] [Full Text] [Related]

  • 11. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Ren H, Aleksunes LM, Wood C, Vallanat B, George MH, Klaassen CD, Corton JC.
    Toxicol Sci; 2010 Jan 01; 113(1):45-59. PubMed ID: 19850644
    [Abstract] [Full Text] [Related]

  • 12. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA, Thomas M, Winter S, Damm G, Seehofer D, Burk O, Schwab M, Zanger UM.
    Biochim Biophys Acta; 2016 Sep 01; 1859(9):1218-1227. PubMed ID: 26994748
    [Abstract] [Full Text] [Related]

  • 13. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
    Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG.
    Toxicol Sci; 2014 Jun 01; 139(2):501-11. PubMed ID: 24690595
    [Abstract] [Full Text] [Related]

  • 14. Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver.
    Cholico GN, Nault R, Zacharewski TR.
    Int J Mol Sci; 2022 Jan 29; 23(3):. PubMed ID: 35163483
    [Abstract] [Full Text] [Related]

  • 15. Age-Specific Regulation of Drug-Processing Genes in Mouse Liver by Ligands of Xenobiotic-Sensing Transcription Factors.
    Li CY, Renaud HJ, Klaassen CD, Cui JY.
    Drug Metab Dispos; 2016 Jul 29; 44(7):1038-49. PubMed ID: 26577535
    [Abstract] [Full Text] [Related]

  • 16. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats.
    Haines C, Chatham LR, Vardy A, Elcombe CR, Foster JR, Lake BG.
    Xenobiotica; 2019 Feb 29; 49(2):227-238. PubMed ID: 29424600
    [Abstract] [Full Text] [Related]

  • 17. Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.
    Petrick JS, Klaassen CD.
    Drug Metab Dispos; 2007 Oct 29; 35(10):1806-15. PubMed ID: 17627975
    [Abstract] [Full Text] [Related]

  • 18. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S, Billy LJ, Chang S, Gonzalez FJ, Patterson AD, Peters JM.
    Toxicology; 2022 Jan 15; 465():153056. PubMed ID: 34861291
    [Abstract] [Full Text] [Related]

  • 19. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD, Jackson JP, Lickteig AJ, Augustine LM, Cherrington NJ.
    Arch Toxicol; 2008 Dec 15; 82(12):959-64. PubMed ID: 18488193
    [Abstract] [Full Text] [Related]

  • 20. Regulation of Hepatic Long Noncoding RNAs by Pregnane X Receptor and Constitutive Androstane Receptor Agonists in Mouse Liver.
    Dempsey JL, Cui JY.
    Drug Metab Dispos; 2019 Mar 15; 47(3):329-339. PubMed ID: 30593543
    [Abstract] [Full Text] [Related]

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