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Journal Abstract Search

176 related items for PubMed ID: 38843135

  • 1. Modeling transthyretin (TTR) amyloid diseases, from monomer to amyloid fibrils.
    Criddle RS, Hansen LD, Woodfield BF, Tolley HD.
    PLoS One; 2024; 19(6):e0304891. PubMed ID: 38843135
    [Abstract] [Full Text] [Related]

  • 2. Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition.
    Saelices L, Chung K, Lee JH, Cohn W, Whitelegge JP, Benson MD, Eisenberg DS.
    Proc Natl Acad Sci U S A; 2018 Jul 17; 115(29):E6741-E6750. PubMed ID: 29954863
    [Abstract] [Full Text] [Related]

  • 3. Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
    Pinheiro F, Varejão N, Esperante S, Santos J, Velázquez-Campoy A, Reverter D, Pallarès I, Ventura S.
    FEBS J; 2021 Jan 17; 288(1):310-324. PubMed ID: 32324953
    [Abstract] [Full Text] [Related]

  • 4. Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis.
    Schmidt M, Wiese S, Adak V, Engler J, Agarwal S, Fritz G, Westermark P, Zacharias M, Fändrich M.
    Nat Commun; 2019 Nov 01; 10(1):5008. PubMed ID: 31676763
    [Abstract] [Full Text] [Related]

  • 5. Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
    Foguel D, Suarez MC, Ferrão-Gonzales AD, Porto TC, Palmieri L, Einsiedler CM, Andrade LR, Lashuel HA, Lansbury PT, Kelly JW, Silva JL.
    Proc Natl Acad Sci U S A; 2003 Aug 19; 100(17):9831-6. PubMed ID: 12900507
    [Abstract] [Full Text] [Related]

  • 6. Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils.
    Cardoso I, Goldsbury CS, Müller SA, Olivieri V, Wirtz S, Damas AM, Aebi U, Saraiva MJ.
    J Mol Biol; 2002 Apr 12; 317(5):683-95. PubMed ID: 11955017
    [Abstract] [Full Text] [Related]

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  • 9. Structural basis for transthyretin amyloid formation in vitreous body of the eye.
    Iakovleva I, Hall M, Oelker M, Sandblad L, Anan I, Sauer-Eriksson AE.
    Nat Commun; 2021 Dec 08; 12(1):7141. PubMed ID: 34880242
    [Abstract] [Full Text] [Related]

  • 10. A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH.
    Ueda M, Okada M, Mizuguchi M, Kluve-Beckerman B, Kanenawa K, Isoguchi A, Misumi Y, Tasaki M, Ueda A, Kanai A, Sasaki R, Masuda T, Inoue Y, Nomura T, Shinriki S, Shuto T, Kai H, Yamashita T, Matsui H, Benson MD, Ando Y.
    J Biol Chem; 2019 Jul 19; 294(29):11259-11275. PubMed ID: 31167790
    [Abstract] [Full Text] [Related]

  • 11. A Brief Journey through Protein Misfolding in Transthyretin Amyloidosis (ATTR Amyloidosis).
    Gonzalez-Duarte A, Ulloa-Aguirre A.
    Int J Mol Sci; 2021 Dec 06; 22(23):. PubMed ID: 34884963
    [Abstract] [Full Text] [Related]

  • 12. Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations.
    Gustavsson A, Engström U, Westermark P.
    Am J Pathol; 1994 Jun 06; 144(6):1301-11. PubMed ID: 8203468
    [Abstract] [Full Text] [Related]

  • 13. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors.
    Sasaki R, Suico MA, Chosa K, Teranishi Y, Sato T, Kagami A, Kotani S, Kato H, Hitora Y, Tsukamoto S, Yamashita T, Yokoyama T, Mizuguchi M, Kai H, Shuto T.
    J Pharmacol Sci; 2023 Jan 06; 151(1):54-62. PubMed ID: 36522123
    [Abstract] [Full Text] [Related]

  • 14. Potentially amyloidogenic conformational intermediates populate the unfolding landscape of transthyretin: insights from molecular dynamics simulations.
    Rodrigues JR, Simões CJ, Silva CG, Brito RM.
    Protein Sci; 2010 Feb 06; 19(2):202-19. PubMed ID: 19937650
    [Abstract] [Full Text] [Related]

  • 15. The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution.
    Quintas A, Saraiva MJ, Brito RM.
    FEBS Lett; 1997 Dec 01; 418(3):297-300. PubMed ID: 9428731
    [Abstract] [Full Text] [Related]

  • 16. The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.
    Sant'Anna R, Braga C, Varejão N, Pimenta KM, Graña-Montes R, Alves A, Cortines J, Cordeiro Y, Ventura S, Foguel D.
    J Biol Chem; 2014 Oct 10; 289(41):28324-37. PubMed ID: 25086037
    [Abstract] [Full Text] [Related]

  • 17. Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis.
    Köppen J, Kleinschmidt M, Morawski M, Rahfeld JU, Wermann M, Cynis H, Hegenbart U, Daniel C, Roßner S, Schilling S, Schulze A.
    Amyloid; 2024 Sep 10; 31(3):184-194. PubMed ID: 38801321
    [Abstract] [Full Text] [Related]

  • 18. Mechanisms of transthyretin aggregation and toxicity.
    Gasperini RJ, Klaver DW, Hou X, Aguilar MI, Small DH.
    Subcell Biochem; 2012 Sep 10; 65():211-24. PubMed ID: 23225005
    [Abstract] [Full Text] [Related]

  • 19. Amyloid fibril composition and transthyretin gene structure in senile systemic amyloidosis.
    Gustavsson A, Jahr H, Tobiassen R, Jacobson DR, Sletten K, Westermark P.
    Lab Invest; 1995 Nov 10; 73(5):703-8. PubMed ID: 7474944
    [Abstract] [Full Text] [Related]

  • 20. Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology.
    Bergström J, Gustavsson A, Hellman U, Sletten K, Murphy CL, Weiss DT, Solomon A, Olofsson BO, Westermark P.
    J Pathol; 2005 Jun 10; 206(2):224-32. PubMed ID: 15810051
    [Abstract] [Full Text] [Related]

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