These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

142 related items for PubMed ID: 38859853

  • 1. Dopamine pre-treatment impairs the anti-cancer effect of integrated stress response- and TRAIL pathway-inducing ONC201, ONC206 and ONC212 imipridones in pancreatic, colorectal cancer but not DMG cells.
    Zhang Y, Tapinos N, Lulla R, El-Deiry WS.
    Am J Cancer Res; 2024; 14(5):2453-2464. PubMed ID: 38859853
    [Abstract] [Full Text] [Related]

  • 2. Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of the integrated stress response, TRAIL death receptor DR5, reduced ClpX and apoptosis.
    Borsuk R, Zhou L, Chang WI, Zhang Y, Sharma A, Prabhu VV, Tapinos N, Lulla RR, El-Deiry WS.
    Am J Cancer Res; 2021; 11(9):4607-4623. PubMed ID: 34659909
    [Abstract] [Full Text] [Related]

  • 3.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 4. Novel combination of imipridones and histone deacetylase inhibitors demonstrate cytotoxic effect through integrated stress response in pediatric solid tumors.
    Chang WI, Honeyman JN, Zhang J, Lin C, Sharma A, Zhou L, Oliveira J, Tapinos N, Lulla RR, Prabhu VV, El-Deiry WS.
    Am J Cancer Res; 2023; 13(12):6241-6255. PubMed ID: 38187038
    [Abstract] [Full Text] [Related]

  • 5.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 6. Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.
    Przystal JM, Cianciolo Cosentino C, Yadavilli S, Zhang J, Laternser S, Bonner ER, Prasad R, Dawood AA, Lobeto N, Chin Chong W, Biery MC, Myers C, Olson JM, Panditharatna E, Kritzer B, Mourabit S, Vitanza NA, Filbin MG, de Iuliis GN, Dun MD, Koschmann C, Cain JE, Grotzer MA, Waszak SM, Mueller S, Nazarian J.
    Neuro Oncol; 2022 Sep 01; 24(9):1438-1451. PubMed ID: 35157764
    [Abstract] [Full Text] [Related]

  • 7. ONC201 and imipridones: Anti-cancer compounds with clinical efficacy.
    Prabhu VV, Morrow S, Rahman Kawakibi A, Zhou L, Ralff M, Ray J, Jhaveri A, Ferrarini I, Lee Y, Parker C, Zhang Y, Borsuk R, Chang WI, Honeyman JN, Tavora F, Carneiro B, Raufi A, Huntington K, Carlsen L, Louie A, Safran H, Seyhan AA, Tarapore RS, Schalop L, Stogniew M, Allen JE, Oster W, El-Deiry WS.
    Neoplasia; 2020 Dec 01; 22(12):725-744. PubMed ID: 33142238
    [Abstract] [Full Text] [Related]

  • 8. Highly potent dopamine receptor D2 antagonist ONC206 demonstrates anti-tumorigenic activity in endometrial cancer.
    Staley A, Tucker K, Yin Y, Zhang X, Fan Y, Zhang Y, Fang Z, Sun W, Suo H, Zhao X, Zhao Z, Prabhu VV, Allen JE, Zhou C, Bae-Jump VL.
    Am J Cancer Res; 2021 Dec 01; 11(11):5374-5387. PubMed ID: 34873466
    [Abstract] [Full Text] [Related]

  • 9. EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG.
    Zhang Y, Zhou L, Safran H, Borsuk R, Lulla R, Tapinos N, Seyhan AA, El-Deiry WS.
    Neoplasia; 2021 Aug 01; 23(8):792-810. PubMed ID: 34246076
    [Abstract] [Full Text] [Related]

  • 10. ONC206 has anti-tumorigenic effects in human ovarian cancer cells and in a transgenic mouse model of high-grade serous ovarian cancer.
    Tucker K, Yin Y, Staley SA, Zhao Z, Fang Z, Fan Y, Zhang X, Suo H, Sun W, Prabhu VV, Allen JE, Zhou C, Bae-Jump VL.
    Am J Cancer Res; 2022 Aug 01; 12(2):521-536. PubMed ID: 35261784
    [Abstract] [Full Text] [Related]

  • 11. ONC201/TIC10 plus TLY012 anti-cancer effects via apoptosis inhibitor downregulation, stimulation of integrated stress response and death receptor DR5 in gastric adenocarcinoma.
    Parker CS, Zhou L, Prabhu VV, Lee S, Miner TJ, Ross EA, El-Deiry WS.
    Am J Cancer Res; 2023 Aug 01; 13(12):6290-6312. PubMed ID: 38187068
    [Abstract] [Full Text] [Related]

  • 12. Mechanisms of imipridones in targeting mitochondrial metabolism in cancer cells.
    Bonner ER, Waszak SM, Grotzer MA, Mueller S, Nazarian J.
    Neuro Oncol; 2021 Apr 12; 23(4):542-556. PubMed ID: 33336683
    [Abstract] [Full Text] [Related]

  • 13. Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP.
    Lev A, Lulla AR, Wagner J, Ralff MD, Kiehl JB, Zhou Y, Benes CH, Prabhu VV, Oster W, Astsaturov I, Dicker DT, El-Deiry WS.
    Oncotarget; 2017 Oct 10; 8(47):81776-81793. PubMed ID: 29137221
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and Antiproliferative Activity of Novel Imipridone-Ferrocene Hybrids with Triazole and Alkyne Linkers.
    Czuczi T, Murányi J, Bárány P, Móra I, Borbély A, Csala M, Csámpai A.
    Pharmaceuticals (Basel); 2022 Apr 12; 15(4):. PubMed ID: 35455465
    [Abstract] [Full Text] [Related]

  • 15. ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro.
    Zhang Y, Huang Y, Yin Y, Fan Y, Sun W, Zhao X, Tucker K, Staley A, Paraghamian S, Hawkins G, Prabhu V, Allen JE, Zhou C, Bae-Jump V.
    Front Oncol; 2020 Apr 12; 10():577141. PubMed ID: 33194693
    [Abstract] [Full Text] [Related]

  • 16. Role of Dopamine Receptors in the Anticancer Activity of ONC201.
    Kline CLB, Ralff MD, Lulla AR, Wagner JM, Abbosh PH, Dicker DT, Allen JE, El-Deiry WS.
    Neoplasia; 2018 Jan 12; 20(1):80-91. PubMed ID: 29216597
    [Abstract] [Full Text] [Related]

  • 17. Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo.
    Jhaveri AV, Zhou L, Ralff MD, Lee YS, Navaraj A, Carneiro BA, Safran H, Prabhu VV, Ross EA, Lee S, El-Deiry WS.
    Cancer Biol Ther; 2021 Dec 02; 22(10-12):607-618. PubMed ID: 34856854
    [Abstract] [Full Text] [Related]

  • 18. ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells.
    Cao J, Cao F, Wang C, Jiao Z, You Y, Wang X, Zhao W.
    Neoplasia; 2024 Sep 02; 55():101015. PubMed ID: 38944913
    [Abstract] [Full Text] [Related]

  • 19. GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas.
    Batsios G, Udutha S, Taglang C, Gillespie AM, Lau B, Ji S, Phoenix T, Mueller S, Venneti S, Koschmann C, Viswanath P.
    bioRxiv; 2024 Jun 10. PubMed ID: 38915617
    [Abstract] [Full Text] [Related]

  • 20. Targeting dopamine receptor D2 as a novel therapeutic strategy in endometrial cancer.
    Pierce SR, Fang Z, Yin Y, West L, Asher M, Hao T, Zhang X, Tucker K, Staley A, Fan Y, Sun W, Moore DT, Xu C, Tsai YH, Parker J, Prabhu VV, Allen JE, Lee D, Zhou C, Bae-Jump V.
    J Exp Clin Cancer Res; 2021 Feb 08; 40(1):61. PubMed ID: 33557912
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 8.