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Journal Abstract Search

134 related items for PubMed ID: 38869445

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  • 3. Discovery of novel coumarin-based KRAS-G12C inhibitors from virtual screening and Rational structural optimization.
    Shi JT, Hou SJ, Cheng L, Zhang HJ, Mu HX, Wang QS, Wang ZY, Chen SW.
    Bioorg Chem; 2024 Jul; 148():107467. PubMed ID: 38772290
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  • 4. Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRASG12C inhibitors.
    Xiao X, Lai M, Song Z, Geng M, Ding J, Xie H, Zhang A.
    Eur J Med Chem; 2021 Mar 05; 213():113082. PubMed ID: 33309163
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  • 6. Discovery of a new series of imidazo[1,2-a]pyridine compounds as selective c-Met inhibitors.
    Liu TC, Peng X, Ma YC, Ji YC, Chen DQ, Zheng MY, Zhao DM, Cheng MS, Geng MY, Shen JK, Ai J, Xiong B.
    Acta Pharmacol Sin; 2016 May 05; 37(5):698-707. PubMed ID: 27041462
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  • 11. Design, synthesis, and molecular docking study of 3H-imidazole[4,5-c]pyridine derivatives as CDK2 inhibitors.
    Wu YZ, Ying HZ, Xu L, Cheng G, Chen J, Hu YZ, Liu T, Dong XW.
    Arch Pharm (Weinheim); 2018 Jun 05; 351(6):e1700381. PubMed ID: 29708285
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  • 13. Novel amino substituted tetracyclic imidazo[4,5-b]pyridine derivatives: Design, synthesis, antiproliferative activity and DNA/RNA binding study.
    Lončar B, Perin N, Mioč M, Boček I, Grgić L, Kralj M, Tomić S, Stojković MR, Hranjec M.
    Eur J Med Chem; 2021 May 05; 217():113342. PubMed ID: 33751978
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  • 14. Discovery of imidazo[1,2-a]pyridine-thiophene derivatives as FLT3 and FLT3 mutants inhibitors for acute myeloid leukemia through structure-based optimization of an NEK2 inhibitor.
    Zhang L, Lakkaniga NR, Bharate JB, Mcconnell N, Wang X, Kharbanda A, Leung YK, Frett B, Shah NP, Li HY.
    Eur J Med Chem; 2021 Dec 05; 225():113776. PubMed ID: 34479037
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  • 15. Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents.
    Jiao Y, Xin BT, Zhang Y, Wu J, Lu X, Zheng Y, Tang W, Zhou X.
    Eur J Med Chem; 2015 Jan 27; 90():170-83. PubMed ID: 25461318
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  • 16. Scaffold Hopping Approach to a New Series of Pyridine Derivatives as Potent Inhibitors of CDK2.
    Xu X, Yao Q.
    Arch Pharm (Weinheim); 2016 Mar 27; 349(3):224-31. PubMed ID: 26871934
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  • 17. A novel Imidazo[1,2-a]pyridine derivative modulates active KRASG12D through off-like conformational shifts in switch-I and switch-II regions, mimicking inactive KRASG12D.
    Ali Y, Khan AA, Alanazi AM, Fatima S, Kozmon S.
    Int J Biol Macromol; 2024 Jun 27; 270(Pt 2):132477. PubMed ID: 38772459
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  • 19. Discovery of 7H-pyrrolo[2,3-d]pyridine derivatives as potent FAK inhibitors: Design, synthesis, biological evaluation and molecular docking study.
    Wang R, Zhao X, Yu S, Chen Y, Cui H, Wu T, Hao C, Zhao D, Cheng M.
    Bioorg Chem; 2020 Sep 27; 102():104092. PubMed ID: 32707280
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